Systemic Scleroderma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.|A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. (Experimental Factor Ontology, EFO_0000717)
External Link https://www.disgenet.org/browser/0/1/0/C0036421
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Genes

915 genes associated with the disease Systemic Scleroderma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACOT7 acyl-CoA thioesterase 7
ACP3 acid phosphatase 3
ACR acrosin
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVRL1 activin A receptor type II-like 1
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIF1 allograft inflammatory factor 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANXA1 annexin A1
APLN apelin
APLNR apelin receptor
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
ARHGAP31 Rho GTPase activating protein 31
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATF3 activating transcription factor 3
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP8B4 ATPase, class I, type 8B, member 4
AVEN apoptosis, caspase activation inhibitor
AXIN2 axin 2
BANK1 B-cell scaffold protein with ankyrin repeats 1
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BGN biglycan
BICD2 bicaudal D homolog 2 (Drosophila)
BLK BLK proto-oncogene, Src family tyrosine kinase
BLM Bloom syndrome, RecQ helicase-like
BMP6 bone morphogenetic protein 6
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMS1 BMS1 ribosome biogenesis factor
BPI bactericidal/permeability-increasing protein
BST2 bone marrow stromal cell antigen 2
BTG3 BTG family, member 3
C10ORF11 chromosome 10 open reading frame 11
CALCA calcitonin-related polypeptide alpha
CAPG capping protein (actin filament), gelsolin-like
CARD16 caspase recruitment domain family, member 16
CARMIL1 capping protein regulator and myosin 1 linker 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAST calpastatin
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX5 chromobox homolog 5
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL24 chemokine (C-C motif) ligand 24
CCL25 chemokine (C-C motif) ligand 25
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCR8 chemokine (C-C motif) receptor 8
CD14 CD14 molecule
CD163 CD163 molecule
CD19 CD19 molecule
CD1A CD1a molecule
CD1D CD1d molecule
CD22 CD22 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD248 CD248 molecule, endosialin
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD58 CD58 molecule
CD68 CD68 molecule
CD69 CD69 molecule
CD70 CD70 molecule
CD72 CD72 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDCA5 cell division cycle associated 5
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDHR5 cadherin-related family member 5
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK6 cyclin-dependent kinase 6
CDKN2A cyclin-dependent kinase inhibitor 2A
CDSN corneodesmosin
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CEL carboxyl ester lipase
CENPA centromere protein A
CENPB centromere protein B, 80kDa
CENPC centromere protein C
CENPE centromere protein E, 312kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM3 cholinergic receptor, muscarinic 3
CHRM5 cholinergic receptor, muscarinic 5
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCNKB chloride channel, voltage-sensitive Kb
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CNTRL centriolin
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COMP cartilage oligomeric matrix protein
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COX2
CRISP2 cysteine-rich secretory protein 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSAD cysteine sulfinic acid decarboxylase
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSK c-src tyrosine kinase
CST3 cystatin C
CST4 cystatin S
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSG cathepsin G
CTSV cathepsin V
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYCS cytochrome c, somatic
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCN decorin
DDR2 discoidin domain receptor tyrosine kinase 2
DDT D-dopachrome tautomerase
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGKQ diacylglycerol kinase, theta 110kDa
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DIABLO diablo, IAP-binding mitochondrial protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLAT dihydrolipoamide S-acetyltransferase
DLL1 delta-like 1 (Drosophila)
DNAAF3 dynein, axonemal, assembly factor 3
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DNASE1L3 deoxyribonuclease I-like 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOK5 docking protein 5
DPP4 dipeptidyl-peptidase 4
DSG2 desmoglein 2
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
EBI3 Epstein-Barr virus induced 3
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGF epidermal growth factor
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELANE elastase, neutrophil expressed
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENG endoglin
ENHO energy homeostasis associated
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EP300 E1A binding protein p300
EPHA1 EPH receptor A1
EPHB2 EPH receptor B2
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ESR1 estrogen receptor 1
ESYT1 extended synaptotagmin-like protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOSC10 exosome component 10
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F2R coagulation factor II (thrombin) receptor
F8 coagulation factor VIII, procoagulant component
FAM111B family with sequence similarity 111, member B
FAM167A family with sequence similarity 167, member A
FAM20A family with sequence similarity 20, member A
FAS Fas cell surface death receptor
FBL fibrillarin
FBLIM1 filamin binding LIM protein 1
FBN1 fibrillin 1
FBRS fibrosin
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FCRL4 Fc receptor-like 4
FCRL6 Fc receptor-like 6
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF6 fibroblast growth factor 6
FHL5 four and a half LIM domains 5
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FKBP1A FK506 binding protein 1A, 12kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FN1 fibronectin 1
FOLR2 folate receptor 2 (fetal)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL2 FOS-like antigen 2
FOXC1 forkhead box C1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FSTL1 follistatin-like 1
GAB1 GRB2-associated binding protein 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA3 GATA binding protein 3
GCHFR GTP cyclohydrolase I feedback regulator
GDE1 glycerophosphodiester phosphodiesterase 1
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GGCT gamma-glutamylcyclotransferase
GLB1 galactosidase, beta 1
GLI1 GLI family zinc finger 1
GOPC golgi-associated PDZ and coiled-coil motif containing
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPI glucose-6-phosphate isomerase
GRAP2 GRB2-related adaptor protein 2
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
GREM1 gremlin 1, DAN family BMP antagonist
GRN granulin
GSDMA gasdermin A
GSDMB gasdermin B
GSK3B glycogen synthase kinase 3 beta
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GTF2I general transcription factor IIi
GYPA glycophorin A (MNS blood group)
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HBEGF heparin-binding EGF-like growth factor
HDAC5 histone deacetylase 5
HDC histidine decarboxylase
HFE hemochromatosis
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHAT hedgehog acyltransferase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H4A histone cluster 1, H4a
HIST1H4B histone cluster 1, H4b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST1H4E histone cluster 1, H4e
HIST1H4F histone cluster 1, H4f
HIST1H4H histone cluster 1, H4h
HIST1H4I histone cluster 1, H4i
HIST1H4J histone cluster 1, H4j
HIST1H4K histone cluster 1, H4k
HIST1H4L histone cluster 1, H4l
HIST2H4A histone cluster 2, H4a
HIST2H4B histone cluster 2, H4b
HIST4H4 histone cluster 4, H4
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HOXA9 homeobox A9
HOXD13 homeobox D13
HP haptoglobin
HPGDS hematopoietic prostaglandin D synthase
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
HSPG2 heparan sulfate proteoglycan 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IFT122 intraflagellar transport 122
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL11 interleukin 11
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL16 interleukin 16
IL17A interleukin 17A
IL17B interleukin 17B
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL25 interleukin 25
IL26 interleukin 26
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL3 interleukin 3
IL33 interleukin 33
IL34 interleukin 34
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
IL9 interleukin 9
INTS4 integrator complex subunit 4
IRAK1 interleukin-1 receptor-associated kinase 1
IRF4 interferon regulatory factor 4
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB8 integrin, beta 8
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAZF1 JAZF zinc finger 1
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM6B lysine (K)-specific demethylase 6B
KDR kinase insert domain receptor
KIAA0319L KIAA0319-like
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KITLG KIT ligand
KL klotho
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLK1 kallikrein 1
KLK12 kallikrein-related peptidase 12
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT1 keratin 1, type II
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LAG3 lymphocyte-activation gene 3
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LBR lamin B receptor
LEMD3 LEM domain containing 3
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS7 lectin, galactoside-binding, soluble, 7
LGALS7B lectin, galactoside-binding, soluble, 7B
LGALS9 lectin, galactoside-binding, soluble, 9
LIAS lipoic acid synthetase
LIF leukemia inhibitory factor
LIFR leukemia inhibitory factor receptor alpha
LINC00961 long intergenic non-protein coding RNA 961
LMNA lamin A/C
LOC105375355 uroplakin-3b
LOX lysyl oxidase
LOXL2 lysyl oxidase-like 2
LOXL4 lysyl oxidase-like 4
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC34 leucine rich repeat containing 34
LTA lymphotoxin alpha
LTB4R leukotriene B4 receptor
LTBP4 latent transforming growth factor beta binding protein 4
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MBD1 methyl-CpG binding domain protein 1
MBD4 methyl-CpG binding domain protein 4
MBL2 mannose-binding lectin (protein C) 2, soluble
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCAM melanoma cell adhesion molecule
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIP major intrinsic protein of lens fiber
MMD monocyte to macrophage differentiation-associated
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP21 matrix metallopeptidase 21
MMP23B matrix metallopeptidase 23B
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPO myeloperoxidase
MPZ myelin protein zero
MRPS30 mitochondrial ribosomal protein S30
MRTFA myocardin related transcription factor A
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSC musculin
MSH5 mutS homolog 5
MSN moesin
MSR1 macrophage scavenger receptor 1
MT1G metallothionein 1G
MT3 metallothionein 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTPAP mitochondrial poly(A) polymerase
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC22 mucin 22
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYBPH myosin binding protein H
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NANOS2 nanos homolog 2 (Drosophila)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NDN necdin, melanoma antigen (MAGE) family member
NECTIN2 nectin cell adhesion molecule 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NID2 nidogen 2 (osteonidogen)
NKX2-5 NK2 homeobox 5
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH4 notch 4
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NRP1 neuropilin 1
NRP2 neuropilin 2
NT5C1A 5'-nucleotidase, cytosolic IA
NUP85 nucleoporin 85kDa
NXF1 nuclear RNA export factor 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OASL 2'-5'-oligoadenylate synthetase-like
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OSMR oncostatin M receptor
OTUD6B OTU domain containing 6B
OXCT1 3-oxoacid CoA transferase 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P4HB prolyl 4-hydroxylase, beta polypeptide
PAH phenylalanine hydroxylase
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAM peptidylglycine alpha-amidating monooxygenase
PAPOLA poly(A) polymerase alpha
PARP1 poly (ADP-ribose) polymerase 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCM1 pericentriolar material 1
PDAP1 PDGFA associated protein 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PF4 platelet factor 4
PGF placental growth factor
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGM1 phosphoglucomutase 1
PHF21A PHD finger protein 21A
PHRF1 PHD and ring finger domains 1
PI3 peptidase inhibitor 3, skin-derived
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAA phospholipase A2-activating protein
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCL2 phospholipase C-like 2
PLD3 phospholipase D family, member 3
PLD4 phospholipase D family, member 4
PLG plasminogen
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMP22 peripheral myelin protein 22
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POMC proopiomelanocortin
POSTN periostin, osteoblast specific factor
POTEF POTE ankyrin domain family, member F
POTEM POTE ankyrin domain family, member M
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKG1 protein kinase, cGMP-dependent, type I
PRL prolactin
PRPF31 pre-mRNA processing factor 31
PRR12 proline rich 12
PRRT2 proline-rich transmembrane protein 2
PRSS55 protease, serine, 55
PRTN3 proteinase 3
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSORS1C1 psoriasis susceptibility 1 candidate 1
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PVR poliovirus receptor
PXK PX domain containing serine/threonine kinase
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAG2 recombination activating gene 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM45 RNA binding motif protein 45
RBMS3 RNA binding motif, single stranded interacting protein 3
REG3A regenerating islet-derived 3 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RETN resistin
RGCC regulator of cell cycle
RHCE Rh blood group, CcEe antigens
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
RNASE3 ribonuclease, RNase A family, 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RNPS1 RNA binding protein S1, serine-rich domain
RO60 Ro60, Y RNA binding protein
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORC RAR-related orphan receptor C
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPP14 ribonuclease P/MRP 14kDa subunit
RPP38 ribonuclease P/MRP 38kDa subunit
RTCA RNA 3'-terminal phosphate cyclase
RTRAF RNA transcription, translation and transport factor
RUNX3 runt-related transcription factor 3
RXFP1 relaxin/insulin-like family peptide receptor 1
RXRB retinoid X receptor, beta
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
S1PR5 sphingosine-1-phosphate receptor 5
SAMD9L sterile alpha motif domain containing 9-like
SCAF1 SR-related CTD-associated factor 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCLY selenocysteine lyase
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC1 syndecan 1
SDC2 syndecan 2
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEC14L2 SEC14-like 2 (S. cerevisiae)
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD2 SET domain containing 2
SF3B6 splicing factor 3b, subunit 6, 14kDa
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SFTPD surfactant protein D
SHCBP1 SHC SH2-domain binding protein 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SIRT7 sirtuin 7
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMG7 SMG7 nonsense mediated mRNA decay factor
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMOC1 SPARC related modular calcium binding 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI2 snail family zinc finger 2
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOAT1 sterol O-acyltransferase 1
SOD1 superoxide dismutase 1, soluble
SOD3 superoxide dismutase 3, extracellular
SOST sclerostin
SOX2 SRY (sex determining region Y)-box 2
SOX5 SRY (sex determining region Y)-box 5
SP1 Sp1 transcription factor
SPAG9 sperm associated antigen 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPIN1 spindlin 1
SPP1 secreted phosphoprotein 1
SPZ1 spermatogenic leucine zipper 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRPK2 SRSF protein kinase 2
SRY sex determining region Y
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSNA1 Sjogren syndrome nuclear autoantigen 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STING1 stimulator of interferon response cGAMP interactor 1
STK19 serine/threonine kinase 19
SUB1 SUB1 homolog (S. cerevisiae)
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUMO1 small ubiquitin-like modifier 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNE1 spectrin repeat containing, nuclear envelope 1
SYS1 Sys1 golgi trafficking protein
SYT1 synaptotagmin I
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAC1 tachykinin, precursor 1
TAGLN transgelin
TAL1 T-cell acute lymphocytic leukemia 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R13 taste receptor, type 2, member 13
TBK1 TANK-binding kinase 1
TBX1 T-box 1
TBX21 T-box 21
TEK TEK tyrosine kinase, endothelial
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TM7SF2 transmembrane 7 superfamily member 2
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TNNC1 troponin C type 1 (slow)
TNPO3 transportin 3
TNXB tenascin XB
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TPO thyroid peroxidase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRB T cell receptor beta locus
TREX1 three prime repair exonuclease 1
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSHR thyroid stimulating hormone receptor
TSKU tsukushi, small leucine rich proteoglycan
TSLP thymic stromal lymphopoietin
TSPY1 testis specific protein, Y-linked 1
TSPY10 testis specific protein, Y-linked 10
TSPY3 testis specific protein, Y-linked 3
TSSK1B testis-specific serine kinase 1B
TSSK2 testis-specific serine kinase 2
TTN titin
TUBA1C tubulin, alpha 1c
TUSC2 tumor suppressor candidate 2
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TYK2 tyrosine kinase 2
UBE4A ubiquitination factor E4A
UBE4B ubiquitination factor E4B
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase
USO1 USO1 vesicle transport factor
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTS2 urotensin 2
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VIP vasoactive intestinal peptide
VIPR2 vasoactive intestinal peptide receptor 2
VTN vitronectin
VWF von Willebrand factor
WDR11 WD repeat domain 11
WIF1 WNT inhibitory factor 1
WNK1 WNK lysine deficient protein kinase 1
WNT1 wingless-type MMTV integration site family, member 1
WNT3 wingless-type MMTV integration site family, member 3
WRN Werner syndrome, RecQ helicase-like
XCL1 chemokine (C motif) ligand 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XYLT2 xylosyltransferase II
YBX1 Y box binding protein 1
YY1 YY1 transcription factor
ZBP1 Z-DNA binding protein 1
ZC3H10 zinc finger CCCH-type containing 10
ZMPSTE24 zinc metallopeptidase STE24