T cell activation Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. (Gene Ontology, GO_0042110)
External Link http://amigo.geneontology.org/amigo/term/GO_0042110
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Genes

112 genes participating in the T cell activation biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADA adenosine deaminase
AMICA1 adhesion molecule, interacts with CXADR antigen 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CCR7 chemokine (C-C motif) receptor 7
CD1C CD1c molecule
CD2 CD2 molecule
CD247 CD247 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD7 CD7 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CD84 CD84 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CHD7 chromodomain helicase DNA binding protein 7
CLEC7A C-type lectin domain family 7, member A
CRTAM cytotoxic and regulatory T cell molecule
CTPS1 CTP synthase 1
CXADR coxsackie virus and adenovirus receptor
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DLL4 delta-like 4 (Drosophila)
DPP4 dipeptidyl-peptidase 4
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
FKBP1A FK506 binding protein 1A, 12kDa
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GPHRA golgi pH regulator A
GPHRB golgi pH regulator B
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICOSLG inducible T-cell co-stimulator ligand
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNK interferon, kappa
IFNW1 interferon, omega 1
IL2 interleukin 2
IL4 interleukin 4
INS insulin
IRF4 interferon regulatory factor 4
ITK IL2-inducible T-cell kinase
JAG2 jagged 2
KIF13B kinesin family member 13B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LEP leptin
LEPR leptin receptor
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LMBR1L limb development membrane protein 1-like
LY9 lymphocyte antigen 9
MDK midkine (neurite growth-promoting factor 2)
MFAP3 microfibrillar-associated protein 3
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MSN moesin
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCOR2 nuclear receptor corepressor 2
NHEJ1 nonhomologous end-joining factor 1
NLRC3 NLR family, CARD domain containing 3
ORC3 origin recognition complex, subunit 3
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
RAB29 RAB29, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RHOH ras homolog family member H
SCRIB scribbled planar cell polarity protein
SLA2 Src-like-adaptor 2
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SLAMF9 SLAM family member 9
SOX4 SRY (sex determining region Y)-box 4
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRBC1 T cell receptor beta constant 1
TRBC2 T cell receptor beta constant 2
TRDC T cell receptor delta constant
TREML2 triggering receptor expressed on myeloid cells-like 2
TRGC1 T cell receptor gamma constant 1
TRGC2 T cell receptor gamma constant 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa