T-helper 1 cell differentiation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma. (Gene Ontology, GO_0045063)
External Link http://amigo.geneontology.org/amigo/term/GO:0045063
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Genes

7 genes participating in the T-helper 1 cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
CRACR2A calcium release activated channel regulator 2A
HMGB1 high mobility group box 1
LEF1 lymphoid enhancer-binding factor 1
PPP1R9B protein phosphatase 1, regulatory subunit 9B
STAT4 signal transducer and activator of transcription 4
TBX21 T-box 21
TMEM98 transmembrane protein 98