T-helper 17 cell differentiation Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. (Gene Ontology, GO_0072539)
External Link	http://amigo.geneontology.org/amigo/term/GO:0072539
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Genes

11 genes participating in the T-helper 17 cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
BATF	basic leucine zipper transcription factor, ATF-like
IL6	interleukin 6
IL6R	interleukin 6 receptor
IL6ST	interleukin 6 signal transducer
IRF4	interferon regulatory factor 4
JAK1	Janus kinase 1
LY9	lymphocyte antigen 9
RORC	RAR-related orphan receptor C
SLAMF6	SLAM family member 6
SOCS3	suppressor of cytokine signaling 3
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)