T-helper 17 cell lineage commitment Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17. (Gene Ontology, GO_0072540)
External Link http://amigo.geneontology.org/amigo/term/GO:0072540
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Genes

10 genes participating in the T-helper 17 cell lineage commitment biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IRF4 interferon regulatory factor 4
JAK1 Janus kinase 1
LY9 lymphocyte antigen 9
SLAMF6 SLAM family member 6
SOCS3 suppressor of cytokine signaling 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)