T-tubule Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane. (Gene Ontology, GO_0030315)
External Link http://amigo.geneontology.org/amigo/term/GO:0030315
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Genes

37 proteins localized to the T-tubule cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 5.0
AHNAK2 AHNAK nucleoprotein 2 5.0
DYSF dysferlin 5.0
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 5.0
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 5.0
AHNAK AHNAK nucleoprotein 5.0
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 4.0
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 4.0
SCN5A sodium channel, voltage gated, type V alpha subunit 4.0
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 4.0
CAPN3 calpain 3, (p94) 4.0
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 4.0
RTN2 reticulon 2 4.0
SRI sorcin 4.0
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 4.0
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 4.0
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 4.0
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 4.0
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 4.0
FXYD1 FXYD domain containing ion transport regulator 1 4.0
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 4.0
STBD1 starch binding domain 1 4.0
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 4.0
CAV3 caveolin 3 3.0
BIN1 bridging integrator 1 3.0
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 3.0
AKAP6 A kinase (PRKA) anchor protein 6 3.0
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 3.0
GPR75-ASB3 GPR75-ASB3 readthrough 3.0
ANK2 ankyrin 2, neuronal 3.0
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 3.0
SLC30A1 solute carrier family 30 (zinc transporter), member 1 3.0
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 3.0
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 3.0
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 3.0
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 3.0
SCN1B sodium channel, voltage gated, type I beta subunit 3.0