T84 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

332 genes with high or low expression in T84 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
APOOL apolipoprotein O-like 3.41763
PTPRO protein tyrosine phosphatase, receptor type, O 2.84325
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 2.80255
TBC1D12 TBC1 domain family, member 12 2.7628
HEPH hephaestin 2.62506
DEFA6 defensin, alpha 6, Paneth cell-specific 2.61441
ZG16 zymogen granule protein 16 2.58367
SNX13 sorting nexin 13 2.49345
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.47687
DEFA5 defensin, alpha 5, Paneth cell-specific 2.41291
PKP2 plakophilin 2 2.40083
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.39769
SFMBT1 Scm-like with four mbt domains 1 2.27644
FABP1 fatty acid binding protein 1, liver 2.27146
FGFR1OP FGFR1 oncogene partner 2.26036
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 2.22702
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.20772
LRRC19 leucine rich repeat containing 19 2.19412
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 2.17159
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) 2.16471
NOX1 NADPH oxidase 1 2.13866
PDCD6IP programmed cell death 6 interacting protein 2.12154
POF1B premature ovarian failure, 1B 2.11349
MRPL17 mitochondrial ribosomal protein L17 2.10234
COA3 cytochrome c oxidase assembly factor 3 2.10069
MED14 mediator complex subunit 14 2.09582
MYO15B myosin XVB 2.08994
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.08214
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.04948
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.04138
FAR2 fatty acyl CoA reductase 2 2.03116
ASB9 ankyrin repeat and SOCS box containing 9 2.03063
GPA33 glycoprotein A33 (transmembrane) 1.98344
GUCY2C guanylate cyclase 2C 1.95872
CLCA1 chloride channel accessory 1 1.92338
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 1.91685
ACAA1 acetyl-CoA acyltransferase 1 1.90896
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.89161
TRIM31 tripartite motif containing 31 1.88088
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.87077
SGK2 serum/glucocorticoid regulated kinase 2 1.85613
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 1.85363
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 1.83579
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.82422
PECR peroxisomal trans-2-enoyl-CoA reductase 1.82288
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.81194
MOB1A MOB kinase activator 1A 1.81135
ZNF75D zinc finger protein 75D 1.79976
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.78912
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.78118
PTPRB protein tyrosine phosphatase, receptor type, B 1.77272
VIL1 villin 1 1.76706
CENPN centromere protein N 1.75573
OCRL oculocerebrorenal syndrome of Lowe 1.75485
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 1.7519
NUP37 nucleoporin 37kDa 1.7503
EDC3 enhancer of mRNA decapping 3 1.74899
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.74618
ZNF33B zinc finger protein 33B 1.74154
SLC26A3 solute carrier family 26 (anion exchanger), member 3 1.73078
NDC1 NDC1 transmembrane nucleoporin 1.72667
OXSR1 oxidative stress responsive 1 1.72277
MCTS1 malignant T cell amplified sequence 1 1.70121
CLDN3 claudin 3 1.6952
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.69287
OLFM4 olfactomedin 4 1.6916
MLEC malectin 1.68714
ADIPOR2 adiponectin receptor 2 1.67437
DAZAP2 DAZ associated protein 2 1.65169
BCL2L14 BCL2-like 14 (apoptosis facilitator) 1.64729
TMPRSS2 transmembrane protease, serine 2 1.64268
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 1.64216
HOXB9 homeobox B9 1.63634
SELENBP1 selenium binding protein 1 1.62932
MLH1 mutL homolog 1 1.62917
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.61919
TMEM106C transmembrane protein 106C 1.61295
ACSL6 acyl-CoA synthetase long-chain family member 6 1.60386
AK2 adenylate kinase 2 1.60165
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.60088
ZNF200 zinc finger protein 200 1.59935
CDX2 caudal type homeobox 2 1.57255
GPKOW G patch domain and KOW motifs 1.56526
CDX1 caudal type homeobox 1 1.56159
MEP1A meprin A, alpha (PABA peptide hydrolase) 1.56149
MAPRE3 microtubule-associated protein, RP/EB family, member 3 1.56032
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D 1.55611
GAN gigaxonin 1.55557
RPGR retinitis pigmentosa GTPase regulator 1.5553
MYO1A myosin IA 1.55198
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.5506
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 1.54935
COQ3 coenzyme Q3 methyltransferase 1.54727
KIF5B kinesin family member 5B 1.54465
AQR aquarius intron-binding spliceosomal factor 1.54052
SPINK1 serine peptidase inhibitor, Kazal type 1 1.53664
SCT secretin 1.53448
ANKHD1 ankyrin repeat and KH domain containing 1 1.53255
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.53194
GRIK3 glutamate receptor, ionotropic, kainate 3 1.53013
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene 1.52981
PPAP2C phosphatidic acid phosphatase type 2C 1.52756
MRPS35 mitochondrial ribosomal protein S35 1.52574
ALOX15 arachidonate 15-lipoxygenase 1.52494
YIPF6 Yip1 domain family, member 6 1.52358
ZNF263 zinc finger protein 263 1.52156
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 1.52131
USP3 ubiquitin specific peptidase 3 1.52031
TKFC triokinase/FMN cyclase 1.51739
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 1.51488
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.51463
RNF114 ring finger protein 114 1.51179
HKDC1 hexokinase domain containing 1 1.5019
XK X-linked Kx blood group 1.49743
ASL argininosuccinate lyase 1.49664
MYD88 myeloid differentiation primary response 88 1.49522
ARG2 arginase 2 1.49389
RAB21 RAB21, member RAS oncogene family 1.4921
DIAPH2 diaphanous-related formin 2 1.48994
ARAF A-Raf proto-oncogene, serine/threonine kinase 1.47956
ODAM odontogenic, ameloblast asssociated 1.47533
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.47531
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.47141
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.46872
ZNF12 zinc finger protein 12 1.46616
ETV7 ets variant 7 1.46527
LGALS4 lectin, galactoside-binding, soluble, 4 1.46475
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.45769
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.45758
GMDS GDP-mannose 4,6-dehydratase 1.45553
CXCL11 chemokine (C-X-C motif) ligand 11 1.45544
RNF113A ring finger protein 113A 1.45374
RPA3 replication protein A3, 14kDa 1.45221
ADH6 alcohol dehydrogenase 6 (class V) 1.44709
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1.44662
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.44658
PRR13 proline rich 13 1.44169
SAR1B secretion associated, Ras related GTPase 1B 1.44007
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 1.43822
ETNK1 ethanolamine kinase 1 1.43592
CTPS2 CTP synthase 2 1.43565
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.43511
E2F8 E2F transcription factor 8 1.43317
CHPT1 choline phosphotransferase 1 1.43041
ZNF384 zinc finger protein 384 1.42926
FBXO34 F-box protein 34 1.42761
ELP4 elongator acetyltransferase complex subunit 4 1.42479
ACSM3 acyl-CoA synthetase medium-chain family member 3 1.42314
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.41917

low expression

Symbol Name Standardized Value
STK25 serine/threonine kinase 25 -3.53725
DSC3 desmocollin 3 -3.23911
PHOX2A paired-like homeobox 2a -2.75533
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -2.7011
PACS1 phosphofurin acidic cluster sorting protein 1 -2.6637
SETMAR SET domain and mariner transposase fusion gene -2.60116
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.52511
ZNF34 zinc finger protein 34 -2.47537
CEP170 centrosomal protein 170kDa -2.4667
GOLGA8A golgin A8 family, member A -2.40233
TEP1 telomerase-associated protein 1 -2.38428
YPEL5 yippee-like 5 (Drosophila) -2.36704
ZNF696 zinc finger protein 696 -2.35011
WASL Wiskott-Aldrich syndrome-like -2.32402
NRIP3 nuclear receptor interacting protein 3 -2.32243
PAOX polyamine oxidase (exo-N4-amino) -2.30451
BHLHE40 basic helix-loop-helix family, member e40 -2.27676
INHBA inhibin, beta A -2.25859
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -2.24511
SEPT2 septin 2 -2.2193
SIPA1 signal-induced proliferation-associated 1 -2.18422
SEC31A SEC31 homolog A (S. cerevisiae) -2.18194
EVL Enah/Vasp-like -2.17919
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -2.17706
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.17242
CTTNBP2NL CTTNBP2 N-terminal like -2.16925
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit -2.11544
MYO15A myosin XVA -2.10521
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -2.09226
HDLBP high density lipoprotein binding protein -2.07835
MAPK12 mitogen-activated protein kinase 12 -2.07507
DYSF dysferlin -2.05873
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 -2.05154
ISYNA1 inositol-3-phosphate synthase 1 -2.04664
KRT31 keratin 31, type I -2.02234
TCEA2 transcription elongation factor A (SII), 2 -2.01125
ORAI2 ORAI calcium release-activated calcium modulator 2 -2.0063
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -1.98925
ICAM5 intercellular adhesion molecule 5, telencephalin -1.98725
MRAS muscle RAS oncogene homolog -1.97908
NDRG3 NDRG family member 3 -1.97421
TROVE2 TROVE domain family, member 2 -1.9572
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.95677
OBSL1 obscurin-like 1 -1.95102
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -1.93137
RAD23A RAD23 homolog A (S. cerevisiae) -1.91829
PER3 period circadian clock 3 -1.90979
ANXA6 annexin A6 -1.9092
GNRHR gonadotropin-releasing hormone receptor -1.89989
ATM ATM serine/threonine kinase -1.88708
GOLGA8B golgin A8 family, member B -1.87951
SERHL serine hydrolase-like (pseudogene) -1.87391
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -1.87297
SMG6 SMG6 nonsense mediated mRNA decay factor -1.87093
MITF microphthalmia-associated transcription factor -1.86297
MXRA8 matrix-remodelling associated 8 -1.85272
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -1.85016
CALCOCO1 calcium binding and coiled-coil domain 1 -1.84798
KLHL2 kelch-like family member 2 -1.84529
GTDC1 glycosyltransferase-like domain containing 1 -1.8425
MPO myeloperoxidase -1.83398
TOP3A topoisomerase (DNA) III alpha -1.83168
ZNF446 zinc finger protein 446 -1.81196
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 -1.81016
MAPK7 mitogen-activated protein kinase 7 -1.80928
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -1.79964
FOXF1 forkhead box F1 -1.79502
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -1.79068
SYNE1 spectrin repeat containing, nuclear envelope 1 -1.77935
SPAG16 sperm associated antigen 16 -1.77533
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -1.77501
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -1.77379
ELOVL5 ELOVL fatty acid elongase 5 -1.75922
OXNAD1 oxidoreductase NAD-binding domain containing 1 -1.75711
FBXL2 F-box and leucine-rich repeat protein 2 -1.75328
SDCCAG8 serologically defined colon cancer antigen 8 -1.75112
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.74151
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -1.73851
MDFIC MyoD family inhibitor domain containing -1.73697
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -1.73303
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.72566
CCDC88A coiled-coil domain containing 88A -1.72562
FKRP fukutin related protein -1.72525
CD96 CD96 molecule -1.71859
CNTFR ciliary neurotrophic factor receptor -1.7154
FKBP1A FK506 binding protein 1A, 12kDa -1.71437
COL4A6 collagen, type IV, alpha 6 -1.70078
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -1.69863
MPP1 membrane protein, palmitoylated 1, 55kDa -1.69315
FJX1 four jointed box 1 (Drosophila) -1.69177
TOR1AIP2 torsin A interacting protein 2 -1.6867
NOVA2 neuro-oncological ventral antigen 2 -1.68262
SSBP2 single-stranded DNA binding protein 2 -1.68171
TCHH trichohyalin -1.67642
WDR7 WD repeat domain 7 -1.66963
COL18A1 collagen, type XVIII, alpha 1 -1.66696
KDSR 3-ketodihydrosphingosine reductase -1.65821
FBXO2 F-box protein 2 -1.65197
MAP9 microtubule-associated protein 9 -1.64658
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -1.64352
RABAC1 Rab acceptor 1 (prenylated) -1.634
STRA6 stimulated by retinoic acid 6 -1.63318
HHAT hedgehog acyltransferase -1.63152
MTMR9 myotubularin related protein 9 -1.62763
CD72 CD72 molecule -1.62497
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -1.62484
COLGALT2 collagen beta(1-O)galactosyltransferase 2 -1.62383
GFRA1 GDNF family receptor alpha 1 -1.62252
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -1.62169
VCAM1 vascular cell adhesion molecule 1 -1.61851
RIBC2 RIB43A domain with coiled-coils 2 -1.61598
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -1.61229
NNMT nicotinamide N-methyltransferase -1.61155
ABLIM2 actin binding LIM protein family, member 2 -1.60975
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -1.60249
RRAGD Ras-related GTP binding D -1.60186
CLASP1 cytoplasmic linker associated protein 1 -1.59229
RWDD2A RWD domain containing 2A -1.59204
TIPRL TOR signaling pathway regulator -1.57501
TBC1D5 TBC1 domain family, member 5 -1.56918
LY6G6C lymphocyte antigen 6 complex, locus G6C -1.56017
EPHB6 EPH receptor B6 -1.56015
MAGEH1 melanoma antigen family H1 -1.55545
SREK1IP1 SREK1-interacting protein 1 -1.5554
BICD2 bicaudal D homolog 2 (Drosophila) -1.55052
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -1.55034
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -1.54918
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -1.5491
ADGRG2 adhesion G protein-coupled receptor G2 -1.54815
CD93 CD93 molecule -1.54425
FADS2 fatty acid desaturase 2 -1.54224
ICAM1 intercellular adhesion molecule 1 -1.542
ACOX3 acyl-CoA oxidase 3, pristanoyl -1.5375
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -1.53693
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.53642
P3H1 prolyl 3-hydroxylase 1 -1.53062
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 -1.52968
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -1.52385
RPS28 ribosomal protein S28 -1.52257
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -1.52198
HCG4 HLA complex group 4 (non-protein coding) -1.51979
TSSK2 testis-specific serine kinase 2 -1.51648
ZNF271P zinc finger protein 271, pseudogene -1.50985
SCAMP1 secretory carrier membrane protein 1 -1.498
TTBK2 tau tubulin kinase 2 -1.4978
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -1.49736
CH25H cholesterol 25-hydroxylase -1.49419
DTNB dystrobrevin, beta -1.49399
ACYP2 acylphosphatase 2, muscle type -1.48915
AKT3 v-akt murine thymoma viral oncogene homolog 3 -1.48673
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -1.48422
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -1.48104
ACKR3 atypical chemokine receptor 3 -1.47691
OCA2 oculocutaneous albinism II -1.47671
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.47324
GTPBP3 GTP binding protein 3 (mitochondrial) -1.47194
OGFR opioid growth factor receptor -1.47115
SLC35E1 solute carrier family 35, member E1 -1.46605
SIKE1 suppressor of IKBKE 1 -1.45799
XPC xeroderma pigmentosum, complementation group C -1.45638
CDRT4 CMT1A duplicated region transcript 4 -1.45497
NPVF neuropeptide VF precursor -1.45329
PNMA1 paraneoplastic Ma antigen 1 -1.4526
PVT1 Pvt1 oncogene (non-protein coding) -1.45094
MAP7D1 MAP7 domain containing 1 -1.44989
ANGEL2 angel homolog 2 (Drosophila) -1.44927
PLSCR3 phospholipid scramblase 3 -1.44918
FARSA phenylalanyl-tRNA synthetase, alpha subunit -1.44643
SGSM2 small G protein signaling modulator 2 -1.44453
PTGES prostaglandin E synthase -1.44427
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -1.44181
ZFPM2 zinc finger protein, FOG family member 2 -1.43377
MOAP1 modulator of apoptosis 1 -1.43263
COL8A2 collagen, type VIII, alpha 2 -1.43089
MAP3K6 mitogen-activated protein kinase kinase kinase 6 -1.42859
BCL2 B-cell CLL/lymphoma 2 -1.42826
ABHD8 abhydrolase domain containing 8 -1.42567
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -1.42478
CPN2 carboxypeptidase N, polypeptide 2 -1.42116
STXBP1 syntaxin binding protein 1 -1.42055
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 -1.41977
DNM1 dynamin 1 -1.41919
NIN ninein (GSK3B interacting protein) -1.4186