TADA3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description transcriptional adaptor 3|DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 10474)
External Link http://www.ncbi.nlm.nih.gov/gene/10474
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Genes

74 interacting proteins for TADA3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ADPGK ADP-dependent glucokinase
ANKRD12 ankyrin repeat domain 12
AR androgen receptor
ATXN7 ataxin 7
ATXN7L2 ataxin 7-like 2
ATXN7L3 ataxin 7-like 3
ATXN7L3B ataxin 7-like 3B
BRCA1 breast cancer 1, early onset
CCDC101 coiled-coil domain containing 101
CNOT1 CCR4-NOT transcription complex, subunit 1
CNOT10 CCR4-NOT transcription complex, subunit 10
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DEDD death effector domain containing
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
EIF3J eukaryotic translation initiation factor 3, subunit J
ENY2 enhancer of yellow 2 homolog (Drosophila)
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
FAM107B family with sequence similarity 107, member B
HIST1H3B histone cluster 1, H3b
HIST2H3A histone cluster 2, H3a
HNF4A hepatocyte nuclear factor 4, alpha
HSPA8 heat shock 70kDa protein 8
ING5 inhibitor of growth family, member 5
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KDM1A lysine (K)-specific demethylase 1A
KIF7 kinesin family member 7
KLHL23 kelch-like family member 23
MAGEH1 melanoma antigen family H1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MBIP MAP3K12 binding inhibitory protein 1
MSH2 mutS homolog 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NR1I2 nuclear receptor subfamily 1, group I, member 2
NUP205 nucleoporin 205kDa
PIAS4 protein inhibitor of activated STAT, 4
POFUT2 protein O-fucosyltransferase 2
PREPL prolyl endopeptidase-like
RARA retinoic acid receptor, alpha
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RXRA retinoid X receptor, alpha
SAP18 Sin3A-associated protein, 18kDa
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIRT1 sirtuin 1
SND1 staphylococcal nuclease and tudor domain containing 1
SREBF1 sterol regulatory element binding transcription factor 1
SUMO2 small ubiquitin-like modifier 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TADA1 transcriptional adaptor 1
TADA2A transcriptional adaptor 2A
TADA2B transcriptional adaptor 2B
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TP53 tumor protein p53
TRRAP transformation/transcription domain-associated protein
TXNRD2 thioredoxin reductase 2
USP22 ubiquitin specific peptidase 22
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR5 WD repeat domain 5
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YEATS2 YEATS domain containing 2
ZNF7 zinc finger protein 7