| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.376184 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.144056 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.140563 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.119337 |
| FLNA | filamin A, alpha | 0.113413 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.106153 |
| COL5A1 | collagen, type V, alpha 1 | 0.104397 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0960084 |
| PLEC | plectin | 0.0855633 |
| NDRG1 | N-myc downstream regulated 1 | 0.0805882 |
| DST | dystonin | 0.0802333 |
| HDAC9 | histone deacetylase 9 | 0.0750152 |
| NAV1 | neuron navigator 1 | 0.0724017 |
| FSTL1 | follistatin-like 1 | 0.0678707 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0667825 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0658323 |
| SEPTIN9 | septin 9 | 0.0653863 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0630124 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0627395 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0571222 |
| FLNB | filamin B, beta | 0.0547322 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0537464 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0537401 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497175 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0495417 |
| CDH13 | cadherin 13 | 0.0481635 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0471106 |
| APP | amyloid beta (A4) precursor protein | 0.0467658 |
| ANXA2 | annexin A2 | 0.0467579 |
| MAP1B | microtubule-associated protein 1B | 0.0461923 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0457791 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0457249 |
| MSN | moesin | 0.0447714 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436431 |
| TPM3 | tropomyosin 3 | 0.0429165 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0424422 |
| EGFR | epidermal growth factor receptor | 0.041906 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.040574 |
| TRAM2 | translocation associated membrane protein 2 | 0.0402987 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0387961 |
| THBS2 | thrombospondin 2 | 0.0384277 |
| RNF213 | ring finger protein 213 | 0.0382816 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0382509 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0382462 |
| VEGFA | vascular endothelial growth factor A | 0.0356038 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0355379 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0336234 |
| ANKRD11 | ankyrin repeat domain 11 | 0.032178 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0319941 |
| CALR | calreticulin | 0.0319454 |
| CD44 | CD44 molecule (Indian blood group) | 0.031668 |
| DBN1 | drebrin 1 | 0.0313228 |
| L1CAM | L1 cell adhesion molecule | 0.0311294 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0306208 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.030382 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0296264 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0296118 |
| SFTPA2 | surfactant protein A2 | 0.0294882 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0292633 |
| ASPH | aspartate beta-hydroxylase | 0.0291283 |
| PLAT | plasminogen activator, tissue | 0.029068 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0288979 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0275979 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0275931 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270462 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0267767 |
| ADAR | adenosine deaminase, RNA-specific | 0.0264873 |
| COPA | coatomer protein complex, subunit alpha | 0.0260632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0259785 |
| MB21D2 | Mab-21 domain containing 2 | 0.0257823 |
| MINK1 | misshapen-like kinase 1 | 0.02575 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0253551 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0246449 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0242946 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0242063 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0239469 |
| RASAL2 | RAS protein activator like 2 | 0.0239249 |
| DSPP | dentin sialophosphoprotein | 0.0238352 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0233409 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0232905 |
| ACTG1 | actin gamma 1 | 0.0232801 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0232121 |
| FUS | FUS RNA binding protein | 0.0232073 |
| MED15 | mediator complex subunit 15 | 0.0231463 |
| FOSL1 | FOS-like antigen 1 | 0.0231083 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0230238 |
| TPM4 | tropomyosin 4 | 0.0229744 |
| GLIS3 | GLIS family zinc finger 3 | 0.0228773 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0228724 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.022601 |
| C1D | C1D nuclear receptor corepressor | 0.0225957 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0224471 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0223447 |
| NEK7 | NIMA-related kinase 7 | 0.0222781 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0221146 |
| TLE4 | transducin-like enhancer of split 4 | 0.0220397 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0219943 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0219346 |
| CYTH3 | cytohesin 3 | 0.0218878 |
| FAT1 | FAT atypical cadherin 1 | 0.0218791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.260912 |
| TMSB10 | thymosin beta 10 | -0.205373 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.191088 |
| UBC | ubiquitin C | -0.147681 |
| MT2A | metallothionein 2A | -0.09801 |
| LOX | lysyl oxidase | -0.0826783 |
| PTMA | prothymosin, alpha | -0.0806827 |
| COL3A1 | collagen, type III, alpha 1 | -0.0681469 |
| S100A6 | S100 calcium binding protein A6 | -0.0648449 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.064102 |
| COL1A2 | collagen, type I, alpha 2 | -0.0601469 |
| FBN1 | fibrillin 1 | -0.0519244 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0506137 |
| AHNAK | AHNAK nucleoprotein | -0.0463981 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0459402 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0410468 |
| OGA | O-GlcNAcase | -0.0408003 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.039187 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0369155 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0360351 |
| RPS27A | ribosomal protein S27a | -0.0357403 |
| CD99 | CD99 molecule | -0.0351124 |
| COL5A2 | collagen, type V, alpha 2 | -0.0339693 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0331979 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0313209 |
| RTN4 | reticulon 4 | -0.0311771 |
| RPS24 | ribosomal protein S24 | -0.0309069 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0305391 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0286444 |
| MYADM | myeloid-associated differentiation marker | -0.0281935 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0280507 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.027855 |
| RBM25 | RNA binding motif protein 25 | -0.0277098 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0272686 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.025133 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0246687 |
| RPLP1 | ribosomal protein, large, P1 | -0.0242923 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0238161 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0237829 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229794 |
| FTL | ferritin, light polypeptide | -0.0228391 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0226713 |
| SUCNR1 | succinate receptor 1 | -0.0223991 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0220071 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0219545 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0219439 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0213519 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208328 |
| RPS6 | ribosomal protein S6 | -0.0208003 |
| PCBP2 | poly(rC) binding protein 2 | -0.0207989 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0207506 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0203963 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0203027 |
| GNAS | GNAS complex locus | -0.0201016 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.020096 |
| NPR2 | natriuretic peptide receptor 2 | -0.0197828 |
| SBF2 | SET binding factor 2 | -0.0197008 |
| RPLP2 | ribosomal protein, large, P2 | -0.019405 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0192374 |
| RPL23 | ribosomal protein L23 | -0.0190454 |
| MT1X | metallothionein 1X | -0.0188309 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0183378 |
| CSTB | cystatin B (stefin B) | -0.0178664 |
| RPL34 | ribosomal protein L34 | -0.0178639 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.017823 |
| KLHL24 | kelch-like family member 24 | -0.0177221 |
| SPAG9 | sperm associated antigen 9 | -0.0176691 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0176324 |
| S100A9 | S100 calcium binding protein A9 | -0.0175691 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0175516 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0173778 |
| RPL37A | ribosomal protein L37a | -0.0173029 |
| ATP13A3 | ATPase type 13A3 | -0.0171343 |
| RPL28 | ribosomal protein L28 | -0.017087 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0170275 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0169656 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0169131 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0168521 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0167832 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0166146 |
| RPS19 | ribosomal protein S19 | -0.0165525 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0163436 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0163431 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0163429 |
| RHOQ | ras homolog family member Q | -0.0163397 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0163363 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0162361 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0161251 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0159299 |
| PRKD3 | protein kinase D3 | -0.0158893 |
| RPS15 | ribosomal protein S15 | -0.0157241 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0156264 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0156082 |
| RPL35A | ribosomal protein L35a | -0.0154301 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.015226 |
| RNF24 | ring finger protein 24 | -0.0151971 |
| IER3 | immediate early response 3 | -0.0151827 |
| HLA-E | major histocompatibility complex, class I, E | -0.0149017 |
| SDC4 | syndecan 4 | -0.0148734 |
| SP3 | Sp3 transcription factor | -0.0148112 |
