| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.228263 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.179395 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.122547 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.108997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0898098 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0823879 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0804669 |
| MED13L | mediator complex subunit 13-like | 0.0793407 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0790535 |
| GSE1 | Gse1 coiled-coil protein | 0.0773282 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.076169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0743483 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0664844 |
| AFF4 | AF4/FMR2 family, member 4 | 0.066193 |
| SPAG9 | sperm associated antigen 9 | 0.06536 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0622995 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.06215 |
| FNIP1 | folliculin interacting protein 1 | 0.0579089 |
| APP | amyloid beta (A4) precursor protein | 0.0556709 |
| FUS | FUS RNA binding protein | 0.0549837 |
| CTBP2 | C-terminal binding protein 2 | 0.053844 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0535185 |
| MYOF | myoferlin | 0.0517086 |
| SIK3 | SIK family kinase 3 | 0.0514401 |
| SFTPA2 | surfactant protein A2 | 0.0501718 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0483871 |
| RPL3 | ribosomal protein L3 | 0.0479402 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0474763 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0469732 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0466044 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0463381 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0461709 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0445114 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0442156 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0427915 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0423997 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0422766 |
| ERBIN | erbb2 interacting protein | 0.0417851 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0413537 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0413142 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0412979 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0410281 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0409932 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0407649 |
| JMJD1C | jumonji domain containing 1C | 0.0405982 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0400978 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0397081 |
| FLNA | filamin A, alpha | 0.0390329 |
| KIF1A | kinesin family member 1A | 0.0390329 |
| DBN1 | drebrin 1 | 0.038583 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0385278 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.038165 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0379267 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0378749 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0377561 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0370207 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.036997 |
| ANO6 | anoctamin 6 | 0.0369145 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0368618 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0363637 |
| EGR1 | early growth response 1 | 0.0361462 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0360684 |
| SET | SET nuclear proto-oncogene | 0.0357345 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0353761 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0352061 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0349629 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0347851 |
| DENND5A | DENN/MADD domain containing 5A | 0.0347149 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0343448 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0339204 |
| TULP4 | tubby like protein 4 | 0.0337931 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0335377 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0335037 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0331252 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0329715 |
| BRD2 | bromodomain containing 2 | 0.032486 |
| RACK1 | receptor for activated C kinase 1 | 0.0324581 |
| ADM | adrenomedullin | 0.0324296 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.032178 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0315133 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0313476 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0312958 |
| NFYA | nuclear transcription factor Y, alpha | 0.031174 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0310828 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0309716 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0308974 |
| EGFR | epidermal growth factor receptor | 0.0306363 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300536 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0299467 |
| PDE10A | phosphodiesterase 10A | 0.0297194 |
| CABIN1 | calcineurin binding protein 1 | 0.0291295 |
| WDR43 | WD repeat domain 43 | 0.0291223 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0289683 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0288169 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0287792 |
| BCOR | BCL6 corepressor | 0.0285553 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0284397 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0282916 |
| FLNB | filamin B, beta | 0.0282707 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0282266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.150093 |
| CADM2 | cell adhesion molecule 2 | -0.139176 |
| VIM | vimentin | -0.115686 |
| MGP | matrix Gla protein | -0.105872 |
| MEOX2 | mesenchyme homeobox 2 | -0.0803049 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0788487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0738898 |
| PTMA | prothymosin, alpha | -0.065719 |
| COL1A2 | collagen, type I, alpha 2 | -0.0591341 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0582721 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0575991 |
| TMSB10 | thymosin beta 10 | -0.0547417 |
| RPLP1 | ribosomal protein, large, P1 | -0.0527123 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0502089 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484853 |
| CENPF | centromere protein F, 350/400kDa | -0.0468452 |
| RPS24 | ribosomal protein S24 | -0.0468228 |
| RANBP17 | RAN binding protein 17 | -0.044019 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0414777 |
| SEPTIN11 | septin 11 | -0.041043 |
| MEST | mesoderm specific transcript | -0.0392589 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0369549 |
| RPLP2 | ribosomal protein, large, P2 | -0.0349843 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0345154 |
| VCL | vinculin | -0.032806 |
| HMGA2 | high mobility group AT-hook 2 | -0.0314728 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0313389 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0310526 |
| DEK | DEK proto-oncogene | -0.0309118 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304105 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0304057 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0288113 |
| FN1 | fibronectin 1 | -0.0286866 |
| RPL35A | ribosomal protein L35a | -0.0284613 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0283722 |
| RPL34 | ribosomal protein L34 | -0.027804 |
| NFIB | nuclear factor I/B | -0.0274399 |
| RPL32 | ribosomal protein L32 | -0.026211 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0260175 |
| RPS25 | ribosomal protein S25 | -0.0251503 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0245089 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0243755 |
| KLHDC10 | kelch domain containing 10 | -0.0239928 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0237516 |
| NFIA | nuclear factor I/A | -0.0237393 |
| RPS6 | ribosomal protein S6 | -0.0235712 |
| TMEM123 | transmembrane protein 123 | -0.0235402 |
| LMO4 | LIM domain only 4 | -0.0234725 |
| RPS8 | ribosomal protein S8 | -0.0234418 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0233042 |
| CALD1 | caldesmon 1 | -0.023259 |
| RFX7 | regulatory factor X, 7 | -0.0229928 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.022658 |
| FTL | ferritin, light polypeptide | -0.0226439 |
| RPS27A | ribosomal protein S27a | -0.0225347 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0222003 |
| CENPE | centromere protein E, 312kDa | -0.0220869 |
| RPS16 | ribosomal protein S16 | -0.0218876 |
| HMGB1 | high mobility group box 1 | -0.0218615 |
| HDAC8 | histone deacetylase 8 | -0.0215358 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0215298 |
| NBEA | neurobeachin | -0.0212457 |
| DIAPH3 | diaphanous-related formin 3 | -0.0211952 |
| RPL36A | ribosomal protein L36a | -0.0211085 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0207895 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0207417 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0207064 |
| RSU1 | Ras suppressor protein 1 | -0.0206322 |
| RPL19 | ribosomal protein L19 | -0.0203523 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0196743 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0196334 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0196067 |
| UBB | ubiquitin B | -0.0195111 |
| RPL31 | ribosomal protein L31 | -0.0193497 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0192465 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0190977 |
| GNAS | GNAS complex locus | -0.0190454 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0189072 |
| TPM4 | tropomyosin 4 | -0.0185787 |
| MTAP | methylthioadenosine phosphorylase | -0.0183291 |
| GLO1 | glyoxalase I | -0.0180963 |
| RPL4 | ribosomal protein L4 | -0.0179358 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0178204 |
| ATAD5 | ATPase family, AAA domain containing 5 | -0.0178092 |
| UBXN4 | UBX domain protein 4 | -0.0175962 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0173891 |
| SYF2 | SYF2 pre-mRNA-splicing factor | -0.0172052 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0171798 |
| TP53 | tumor protein p53 | -0.0169682 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0168461 |
| RPS21 | ribosomal protein S21 | -0.0166591 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.016647 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0166215 |
| LYPD6 | LY6/PLAUR domain containing 6 | -0.0165959 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0165506 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0165151 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0164002 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0163785 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0162616 |
| COL5A2 | collagen, type V, alpha 2 | -0.0161925 |
