| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.272557 |
| TENM3 | teneurin transmembrane protein 3 | 0.128701 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.128632 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.125053 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.111462 |
| COL5A2 | collagen, type V, alpha 2 | 0.103253 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.089469 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0876228 |
| ZNF608 | zinc finger protein 608 | 0.0875381 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0836864 |
| RAD51B | RAD51 paralog B | 0.079716 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0779223 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0749931 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0740202 |
| CDH18 | cadherin 18, type 2 | 0.0726245 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0693762 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0671853 |
| TOX | thymocyte selection-associated high mobility group box | 0.0653967 |
| MLIP | muscular LMNA-interacting protein | 0.0645621 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0622396 |
| VCL | vinculin | 0.0616466 |
| DST | dystonin | 0.0603541 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0600646 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0598355 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0574225 |
| CADM2 | cell adhesion molecule 2 | 0.0561654 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0561595 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0539124 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0518427 |
| FUS | FUS RNA binding protein | 0.0513856 |
| BNC2 | basonuclin 2 | 0.0511421 |
| RCC1 | regulator of chromosome condensation 1 | 0.0510973 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.051093 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0510766 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.050984 |
| JMJD1C | jumonji domain containing 1C | 0.050216 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0491837 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.048581 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0485228 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0481316 |
| MKI67 | marker of proliferation Ki-67 | 0.0477963 |
| NFIA | nuclear factor I/A | 0.0470679 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0455402 |
| DSCAM | Down syndrome cell adhesion molecule | 0.04451 |
| ENO1 | enolase 1, (alpha) | 0.0439189 |
| DENND1A | DENN/MADD domain containing 1A | 0.043858 |
| WLS | wntless Wnt ligand secretion mediator | 0.042905 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0429041 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.042469 |
| PCNX4 | pecanex 4 | 0.0414338 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0405256 |
| SIK3 | SIK family kinase 3 | 0.0403794 |
| RPL3 | ribosomal protein L3 | 0.0403674 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0398168 |
| JUN | jun proto-oncogene | 0.039752 |
| ADAR | adenosine deaminase, RNA-specific | 0.0394146 |
| BRD2 | bromodomain containing 2 | 0.0393314 |
| UBAP2 | ubiquitin associated protein 2 | 0.0393091 |
| FLNA | filamin A, alpha | 0.0389579 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0389222 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0387756 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0387214 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0379053 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0370572 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0368621 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0366229 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0365593 |
| FAT1 | FAT atypical cadherin 1 | 0.0363306 |
| USP34 | ubiquitin specific peptidase 34 | 0.0362204 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0360438 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.035852 |
| PCM1 | pericentriolar material 1 | 0.0358369 |
| ATP9A | ATPase, class II, type 9A | 0.0352305 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0349139 |
| ZNF644 | zinc finger protein 644 | 0.0345696 |
| ACTG1 | actin gamma 1 | 0.0344882 |
| CREBBP | CREB binding protein | 0.0343642 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0341108 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339173 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0338817 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0338629 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0338128 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0336057 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0334935 |
| ZFHX4 | zinc finger homeobox 4 | 0.0334687 |
| PNN | pinin, desmosome associated protein | 0.0334477 |
| BPTF | bromodomain PHD finger transcription factor | 0.033435 |
| ENAH | enabled homolog (Drosophila) | 0.0332064 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.032927 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0328511 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0323758 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0321748 |
| RPS3 | ribosomal protein S3 | 0.0320179 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0319907 |
| SET | SET nuclear proto-oncogene | 0.0312885 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0308167 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0308074 |
| NEBL | nebulette | 0.030617 |
| RACK1 | receptor for activated C kinase 1 | 0.0305029 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0304328 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0424203 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331333 |
| NGLY1 | N-glycanase 1 | -0.0285907 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0278313 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0273381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0256826 |
| FOXO3 | forkhead box O3 | -0.0250937 |
| RPS24 | ribosomal protein S24 | -0.0250128 |
| MYL12B | myosin, light chain 12B, regulatory | -0.024089 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0235017 |
| TMSB10 | thymosin beta 10 | -0.023264 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0230297 |
| HMGB1 | high mobility group box 1 | -0.0230287 |
| RPLP1 | ribosomal protein, large, P1 | -0.0220319 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0217645 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0216379 |
| ATRN | attractin | -0.0211538 |
| EFNA5 | ephrin-A5 | -0.0199381 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0197103 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0190586 |
| TPD52 | tumor protein D52 | -0.018069 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0179166 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.01742 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0170684 |
| USP3 | ubiquitin specific peptidase 3 | -0.0170091 |
| FAM162A | family with sequence similarity 162, member A | -0.016357 |
| HMGA1 | high mobility group AT-hook 1 | -0.0163452 |
| EMP1 | epithelial membrane protein 1 | -0.0163437 |
| RPL34 | ribosomal protein L34 | -0.0163151 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0161498 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0153015 |
| RTN4 | reticulon 4 | -0.0152928 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0151898 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0151369 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0149459 |
| MIDN | midnolin | -0.0141588 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0138525 |
| SEPTIN10 | septin 10 | -0.0137982 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0136214 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0135183 |
| RPS28 | ribosomal protein S28 | -0.0133076 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0132309 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0131415 |
| ZFP64 | ZFP64 zinc finger protein | -0.0129774 |
| RBM25 | RNA binding motif protein 25 | -0.0129586 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0127598 |
| FAM117B | family with sequence similarity 117, member B | -0.0127489 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0127406 |
| TMEM41B | transmembrane protein 41B | -0.0127168 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0126103 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0124903 |
| DEK | DEK proto-oncogene | -0.0124392 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0124383 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0122546 |
| PFN1 | profilin 1 | -0.0121146 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0120984 |
| TXNRD1 | thioredoxin reductase 1 | -0.0120296 |
| NOP58 | NOP58 ribonucleoprotein | -0.0119335 |
| ZNF544 | zinc finger protein 544 | -0.0118788 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0115602 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0115276 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.011486 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0114065 |
| INSIG2 | insulin induced gene 2 | -0.0113939 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0113724 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0113338 |
| KPNB1 | karyopherin (importin) beta 1 | -0.011285 |
| VIM | vimentin | -0.0112234 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0112036 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0111256 |
| FTL | ferritin, light polypeptide | -0.0110879 |
| RPLP2 | ribosomal protein, large, P2 | -0.0108863 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -0.0108143 |
| S100A9 | S100 calcium binding protein A9 | -0.0108067 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.010728 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0106496 |
| MACO1 | macoilin 1 | -0.0106476 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0106366 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0104495 |
| RPL35A | ribosomal protein L35a | -0.010424 |
| SEPTIN7 | septin 7 | -0.0104099 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0103273 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0102961 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0100919 |
| PTCH1 | patched 1 | -0.0099981 |
| WDR45B | WD repeat domain 45B | -0.00991111 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | -0.00981406 |
| PCDH11X | protocadherin 11 X-linked | -0.00980743 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.00976891 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.00971597 |
| TTK | TTK protein kinase | -0.00968252 |
| KLHL24 | kelch-like family member 24 | -0.00964254 |
| KYAT3 | kynurenine aminotransferase 3 | -0.00958499 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00954551 |
| WRN | Werner syndrome, RecQ helicase-like | -0.00952329 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.00940172 |
| CCND1 | cyclin D1 | -0.00935819 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0093363 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00928068 |
| BTG3 | BTG family, member 3 | -0.00927171 |
