| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOL1 | apolipoprotein L, 1 | 0.151219 |
| ASPH | aspartate beta-hydroxylase | 0.145846 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.118822 |
| SMAD3 | SMAD family member 3 | 0.118147 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.104983 |
| FNDC3B | fibronectin type III domain containing 3B | 0.103789 |
| NDRG1 | N-myc downstream regulated 1 | 0.103187 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0993356 |
| B2M | beta-2-microglobulin | 0.0991498 |
| APP | amyloid beta (A4) precursor protein | 0.0989375 |
| KRT19 | keratin 19, type I | 0.0961734 |
| LAMC2 | laminin, gamma 2 | 0.0921706 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0892056 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0874697 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0827183 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.079384 |
| EFNA5 | ephrin-A5 | 0.0783108 |
| PLEC | plectin | 0.0781473 |
| TGM2 | transglutaminase 2 | 0.0754539 |
| VEGFA | vascular endothelial growth factor A | 0.0728591 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0723948 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0712472 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0671718 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0670597 |
| LAMB3 | laminin, beta 3 | 0.0668054 |
| ENO1 | enolase 1, (alpha) | 0.0666023 |
| RNF213 | ring finger protein 213 | 0.0665742 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.065346 |
| RAD51B | RAD51 paralog B | 0.0620516 |
| HLA-B | major histocompatibility complex, class I, B | 0.0611466 |
| CP | ceruloplasmin (ferroxidase) | 0.0607139 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.059255 |
| LAMA4 | laminin, alpha 4 | 0.0589313 |
| TMSB4X | thymosin beta 4, X-linked | 0.0584824 |
| MYOF | myoferlin | 0.0576992 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0574232 |
| MX1 | MX dynamin-like GTPase 1 | 0.0573288 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0566459 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0564135 |
| HPCAL1 | hippocalcin-like 1 | 0.055091 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0549615 |
| MMP7 | matrix metallopeptidase 7 | 0.053143 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0529979 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0523613 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0517995 |
| LCN2 | lipocalin 2 | 0.0517201 |
| ANKRD11 | ankyrin repeat domain 11 | 0.050557 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.049234 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0483643 |
| PLAU | plasminogen activator, urokinase | 0.0483169 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0482526 |
| ANXA2 | annexin A2 | 0.0479436 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0474951 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0470292 |
| APOL2 | apolipoprotein L, 2 | 0.0468051 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.04651 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0464345 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0461347 |
| CANX | calnexin | 0.0459528 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0456901 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0453724 |
| STC2 | stanniocalcin 2 | 0.0453322 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0449632 |
| CMIP | c-Maf inducing protein | 0.0447497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0438231 |
| KIAA1217 | KIAA1217 | 0.0432511 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0428293 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.042694 |
| HDAC9 | histone deacetylase 9 | 0.0424035 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0422532 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0422176 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.041854 |
| AHNAK | AHNAK nucleoprotein | 0.0417989 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0412103 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0411698 |
| RUNX1 | runt-related transcription factor 1 | 0.0410977 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0409703 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0402886 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0392925 |
| LOC112694756 | uncharaterized LOC112694756 | 0.039182 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0390688 |
| SFTPA2 | surfactant protein A2 | 0.0382316 |
| SEPTIN9 | septin 9 | 0.0381026 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0379745 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0371664 |
| LMNA | lamin A/C | 0.0368402 |
| RNASET2 | ribonuclease T2 | 0.036345 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0362037 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0360136 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.035964 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0356331 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0354621 |
| RPL23 | ribosomal protein L23 | 0.0349325 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0347492 |
| ATXN1 | ataxin 1 | 0.0344983 |
| ANXA4 | annexin A4 | 0.0344107 |
| PGK1 | phosphoglycerate kinase 1 | 0.033994 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0339847 |
| CD44 | CD44 molecule (Indian blood group) | 0.0339622 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0339433 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0947768 |
| SPAG9 | sperm associated antigen 9 | -0.0811915 |
| TSC22D2 | TSC22 domain family, member 2 | -0.064798 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0432537 |
| TMSB10 | thymosin beta 10 | -0.0430397 |
| RTN4 | reticulon 4 | -0.036139 |
| MCU | mitochondrial calcium uniporter | -0.0357159 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.034927 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0325149 |
| YTHDC1 | YTH domain containing 1 | -0.0322471 |
| ABI1 | abl-interactor 1 | -0.0314105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0284264 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0273999 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0269349 |
| CCNL1 | cyclin L1 | -0.0266195 |
| POTEF | POTE ankyrin domain family, member F | -0.0249034 |
| CD2AP | CD2-associated protein | -0.0236928 |
| MT1X | metallothionein 1X | -0.0234345 |
| VMP1 | vacuole membrane protein 1 | -0.0225642 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0219889 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0215368 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0211943 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0210379 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0209129 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.020651 |
| MYO6 | myosin VI | -0.020603 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0204788 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0203385 |
| CLDN4 | claudin 4 | -0.0202815 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0201392 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0199568 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0194411 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0193916 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0191665 |
| ATOSA | atos homolog A | -0.0189824 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0186019 |
| RCOR1 | REST corepressor 1 | -0.0184891 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0184272 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0183771 |
| ZFP36 | ZFP36 ring finger protein | -0.0181476 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0178824 |
| SEC24A | SEC24 family member A | -0.0174837 |
| PLS3 | plastin 3 | -0.0169866 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0168002 |
| NEK7 | NIMA-related kinase 7 | -0.0166473 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0165412 |
| USP3 | ubiquitin specific peptidase 3 | -0.0165085 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0164931 |
| NPTN | neuroplastin | -0.0160675 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0160495 |
| RAB18 | RAB18, member RAS oncogene family | -0.015906 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0156266 |
| TMEM165 | transmembrane protein 165 | -0.0150877 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0150239 |
| FOXO3 | forkhead box O3 | -0.0147712 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0147116 |
| SCFD1 | sec1 family domain containing 1 | -0.014692 |
| JMJD1C | jumonji domain containing 1C | -0.0146696 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0146317 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0144926 |
| ZNF207 | zinc finger protein 207 | -0.0142866 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0142249 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0141915 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0141039 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0139289 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0138883 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0138795 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0138489 |
| ZNF292 | zinc finger protein 292 | -0.013784 |
| SRP54 | signal recognition particle 54kDa | -0.0136928 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0136844 |
| MYO5B | myosin VB | -0.0136526 |
| USP53 | ubiquitin specific peptidase 53 | -0.0135369 |
| RLF | rearranged L-myc fusion | -0.0134967 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0134874 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0133965 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0133228 |
| PRKCI | protein kinase C, iota | -0.0132595 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0132393 |
| LMO7 | LIM domain 7 | -0.0132371 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0131 |
| DUSP5 | dual specificity phosphatase 5 | -0.0129694 |
| KIF13B | kinesin family member 13B | -0.0129658 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0129046 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0127627 |
| IRF6 | interferon regulatory factor 6 | -0.0127529 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0127482 |
| MEF2A | myocyte enhancer factor 2A | -0.0125872 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.012551 |
| FAM162A | family with sequence similarity 162, member A | -0.0125051 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0124237 |
| ARF4 | ADP-ribosylation factor 4 | -0.0123629 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0123576 |
| NUP58 | nucleoporin 58 | -0.0123351 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0123328 |
| DHFR | dihydrofolate reductase | -0.0121907 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0120626 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.012011 |
| WASF2 | WAS protein family, member 2 | -0.0120063 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0119342 |
