| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.22682 |
| RNF213 | ring finger protein 213 | 0.215328 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.16905 |
| MACC1 | metastasis associated in colon cancer 1 | 0.152728 |
| LMO7 | LIM domain 7 | 0.118085 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.110339 |
| SMAD3 | SMAD family member 3 | 0.102893 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.102273 |
| FAT1 | FAT atypical cadherin 1 | 0.0871062 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0825671 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0771605 |
| TNNC1 | troponin C type 1 (slow) | 0.0770507 |
| HKDC1 | hexokinase domain containing 1 | 0.073443 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0726484 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0723535 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0706655 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.069425 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0689824 |
| LCN2 | lipocalin 2 | 0.067404 |
| DST | dystonin | 0.0665143 |
| MLPH | melanophilin | 0.0619977 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0619052 |
| PDZD8 | PDZ domain containing 8 | 0.0602313 |
| MYO5B | myosin VB | 0.0599126 |
| MX1 | MX dynamin-like GTPase 1 | 0.0592808 |
| TJP1 | tight junction protein 1 | 0.0573252 |
| INTS6 | integrator complex subunit 6 | 0.0570955 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0549521 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0544186 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0535889 |
| ZNF292 | zinc finger protein 292 | 0.0535226 |
| B2M | beta-2-microglobulin | 0.0531248 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0517929 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0513286 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0512373 |
| MUC13 | mucin 13, cell surface associated | 0.050658 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0493636 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0492931 |
| FRMD5 | FERM domain containing 5 | 0.0488904 |
| ETV6 | ets variant 6 | 0.0488206 |
| ADAR | adenosine deaminase, RNA-specific | 0.0480448 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0478944 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0475253 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0471936 |
| VEGFA | vascular endothelial growth factor A | 0.0467055 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.046611 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0461237 |
| FNIP2 | folliculin interacting protein 2 | 0.0460052 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.045929 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0449397 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0424343 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0419892 |
| MSI2 | musashi RNA-binding protein 2 | 0.041594 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0415132 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.041413 |
| APP | amyloid beta (A4) precursor protein | 0.0408914 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0406986 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0400399 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0400302 |
| RUNX1 | runt-related transcription factor 1 | 0.0393068 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.039211 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0389289 |
| VCL | vinculin | 0.0386211 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0384168 |
| SIK3 | SIK family kinase 3 | 0.0383784 |
| TRIM2 | tripartite motif containing 2 | 0.0375056 |
| FNIP1 | folliculin interacting protein 1 | 0.0374064 |
| KYNU | kynureninase | 0.0359326 |
| RND3 | Rho family GTPase 3 | 0.0343098 |
| TMEM123 | transmembrane protein 123 | 0.0341775 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0340744 |
| MCU | mitochondrial calcium uniporter | 0.0334138 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0332697 |
| FHL2 | four and a half LIM domains 2 | 0.0331566 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0331391 |
| MED13 | mediator complex subunit 13 | 0.0330205 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0326779 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0323265 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0314039 |
| STK24 | serine/threonine kinase 24 | 0.0313472 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0311451 |
| RBM47 | RNA binding motif protein 47 | 0.030733 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0305994 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0300232 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0299817 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0299429 |
| DUSP10 | dual specificity phosphatase 10 | 0.029878 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0294636 |
| YAP1 | Yes-associated protein 1 | 0.0293765 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0293292 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0292365 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0291269 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0288092 |
| MYO1E | myosin IE | 0.0287678 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0284209 |
| MAP7 | microtubule-associated protein 7 | 0.0283962 |
| PKM | pyruvate kinase, muscle | 0.0281922 |
| MX2 | MX dynamin-like GTPase 2 | 0.0280954 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.027619 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0273851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.1195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0922131 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.085275 |
| PTMA | prothymosin, alpha | -0.0837505 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0660032 |
| EZR | ezrin | -0.0576912 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0503089 |
| ITGA6 | integrin, alpha 6 | -0.0428594 |
| SDC4 | syndecan 4 | -0.0428488 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.039203 |
| SQSTM1 | sequestosome 1 | -0.0346299 |
| DIAPH3 | diaphanous-related formin 3 | -0.0337094 |
| NPSR1 | neuropeptide S receptor 1 | -0.0333839 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0331624 |
| S100A6 | S100 calcium binding protein A6 | -0.032928 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0324059 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0311397 |
| TMSB10 | thymosin beta 10 | -0.0310283 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0304899 |
| TNS4 | tensin 4 | -0.0304485 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0290539 |
| EGR1 | early growth response 1 | -0.0286342 |
| AHNAK | AHNAK nucleoprotein | -0.0285579 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0276227 |
| RPL35A | ribosomal protein L35a | -0.0274075 |
| LYZ | lysozyme | -0.0273762 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0273332 |
| COG6 | component of oligomeric golgi complex 6 | -0.0270909 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0270869 |
| AGR2 | anterior gradient 2 | -0.0269276 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0264327 |
| RPL34 | ribosomal protein L34 | -0.0262802 |
| MKI67 | marker of proliferation Ki-67 | -0.0255299 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0251891 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0251593 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0251391 |
| NDRG1 | N-myc downstream regulated 1 | -0.0249185 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0248203 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0248165 |
| RPS24 | ribosomal protein S24 | -0.0238514 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0237149 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0235945 |
| HMGB1 | high mobility group box 1 | -0.0235826 |
| RPLP1 | ribosomal protein, large, P1 | -0.0234615 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0229197 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0226105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0224674 |
| CENPF | centromere protein F, 350/400kDa | -0.0221429 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0215418 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0213086 |
| GNAS | GNAS complex locus | -0.0210679 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0208561 |
| HLA-E | major histocompatibility complex, class I, E | -0.0206788 |
| TMEM263 | transmembrane protein 263 | -0.0206705 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0205569 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0203888 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0201584 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0201088 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0198808 |
| S100P | S100 calcium binding protein P | -0.019749 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0194387 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.019299 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0189062 |
| BRCA2 | breast cancer 2, early onset | -0.0189016 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0188648 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0187981 |
| WASF2 | WAS protein family, member 2 | -0.0186986 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0186484 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.018641 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0184874 |
| IRF1 | interferon regulatory factor 1 | -0.0183528 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0182534 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0179847 |
| IFT88 | intraflagellar transport 88 | -0.0177733 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0177389 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0177062 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0176649 |
| CTSD | cathepsin D | -0.0174863 |
| ANXA2 | annexin A2 | -0.0172672 |
| LDLR | low density lipoprotein receptor | -0.0172564 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0172526 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.017042 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0170034 |
| RRM2 | ribonucleotide reductase M2 | -0.0168714 |
| HDLBP | high density lipoprotein binding protein | -0.0168417 |
| SMIM14 | small integral membrane protein 14 | -0.0163175 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0163138 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0161921 |
| HM13 | histocompatibility (minor) 13 | -0.0161608 |
| RPS6 | ribosomal protein S6 | -0.0159437 |
| MORF4L2 | mortality factor 4 like 2 | -0.015813 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0158002 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0157537 |
| VIM | vimentin | -0.0157237 |
| DEK | DEK proto-oncogene | -0.0157169 |
| FOSL1 | FOS-like antigen 1 | -0.015641 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0156088 |
| CLYBL | citrate lyase beta like | -0.0156081 |
| TMEM62 | transmembrane protein 62 | -0.0154449 |
| CALU | calumenin | -0.015384 |
