| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A1 | collagen, type V, alpha 1 | 0.223207 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.162234 |
| PLEC | plectin | 0.15287 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.1472 |
| EXT1 | exostosin glycosyltransferase 1 | 0.145465 |
| COL6A3 | collagen, type VI, alpha 3 | 0.14151 |
| NAV1 | neuron navigator 1 | 0.128635 |
| CD44 | CD44 molecule (Indian blood group) | 0.128205 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.119938 |
| FN1 | fibronectin 1 | 0.119813 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119767 |
| VEGFA | vascular endothelial growth factor A | 0.0978947 |
| SEPTIN9 | septin 9 | 0.0958073 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0895345 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0891201 |
| HMGA2 | high mobility group AT-hook 2 | 0.0873321 |
| DST | dystonin | 0.0827567 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0790632 |
| ASPH | aspartate beta-hydroxylase | 0.0756414 |
| FLNA | filamin A, alpha | 0.0712297 |
| NDRG1 | N-myc downstream regulated 1 | 0.0704293 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0647497 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0619647 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0558243 |
| MYO10 | myosin X | 0.0552544 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0540477 |
| ANXA2 | annexin A2 | 0.0522294 |
| HSPA8 | heat shock 70kDa protein 8 | 0.051044 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0505568 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0498585 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0494166 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0490615 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0486697 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0478097 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0473248 |
| ENO1 | enolase 1, (alpha) | 0.0472685 |
| LOXL2 | lysyl oxidase-like 2 | 0.0450143 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0447723 |
| MLPH | melanophilin | 0.0433772 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425191 |
| MSN | moesin | 0.0422955 |
| ATXN1 | ataxin 1 | 0.0417875 |
| PRKCA | protein kinase C, alpha | 0.0415575 |
| EGFR | epidermal growth factor receptor | 0.0412455 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0405312 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0402205 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0398768 |
| SMAD3 | SMAD family member 3 | 0.039391 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0393496 |
| PCBP3 | poly(rC) binding protein 3 | 0.0391409 |
| SMYD3 | SET and MYND domain containing 3 | 0.0388164 |
| ACTN1 | actinin, alpha 1 | 0.0383198 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0382745 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0382199 |
| CLMP | CXADR-like membrane protein | 0.0379288 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0379157 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0378156 |
| PRELID2 | PRELI domain containing 2 | 0.0377993 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0377488 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0373308 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0367375 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0364785 |
| ACTG1 | actin gamma 1 | 0.0362754 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0361992 |
| VCL | vinculin | 0.0360753 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0355495 |
| INTS6 | integrator complex subunit 6 | 0.0355273 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0349069 |
| AHNAK | AHNAK nucleoprotein | 0.0347519 |
| BPTF | bromodomain PHD finger transcription factor | 0.03457 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0344909 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0341751 |
| NAV2 | neuron navigator 2 | 0.0339727 |
| FAT1 | FAT atypical cadherin 1 | 0.0338986 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0335704 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0334567 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0329181 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0324836 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0322733 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0321341 |
| RAI14 | retinoic acid induced 14 | 0.0321333 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0320955 |
| LAMB3 | laminin, beta 3 | 0.0319586 |
| FLNB | filamin B, beta | 0.0319385 |
| TPM3 | tropomyosin 3 | 0.0314779 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.031467 |
| STC1 | stanniocalcin 1 | 0.0312708 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0312699 |
| SFTPA2 | surfactant protein A2 | 0.0309752 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0305301 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0303366 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0301213 |
| GLIS3 | GLIS family zinc finger 3 | 0.0298617 |
| TGFB1 | transforming growth factor, beta 1 | 0.0297392 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0292674 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.029227 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0291815 |
| PODXL | podocalyxin-like | 0.0291709 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0291577 |
| CALR | calreticulin | 0.0290176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.0779222 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0749836 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0718174 |
| VIM | vimentin | -0.060266 |
| FAM13A | family with sequence similarity 13, member A | -0.0539207 |
| TMSB10 | thymosin beta 10 | -0.0478374 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0463592 |
| USP3 | ubiquitin specific peptidase 3 | -0.0455298 |
| ZNF292 | zinc finger protein 292 | -0.0420108 |
| IER3 | immediate early response 3 | -0.0351011 |
| RLF | rearranged L-myc fusion | -0.0344079 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0344073 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0319882 |
| WDR45B | WD repeat domain 45B | -0.0307214 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0298041 |
| SPAG9 | sperm associated antigen 9 | -0.0288534 |
| OGA | O-GlcNAcase | -0.0260888 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0259187 |
| FAM162A | family with sequence similarity 162, member A | -0.0257856 |
| RTN4 | reticulon 4 | -0.0249487 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0241162 |
| FTL | ferritin, light polypeptide | -0.0226856 |
| GOLGA4 | golgin A4 | -0.0226681 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0224719 |
| RNF145 | ring finger protein 145 | -0.0224392 |
| RNF24 | ring finger protein 24 | -0.0221812 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0220047 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0218811 |
| ADM | adrenomedullin | -0.0217229 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0200995 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.019669 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0196347 |
| QKI | QKI, KH domain containing, RNA binding | -0.018958 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0187728 |
| NUP58 | nucleoporin 58 | -0.0185973 |
| SEC24A | SEC24 family member A | -0.0185803 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0185667 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0184962 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0179858 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.017869 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0177532 |
| NGLY1 | N-glycanase 1 | -0.0174246 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0174215 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0173748 |
| TPX2 | TPX2, microtubule-associated | -0.0172559 |
| RPS24 | ribosomal protein S24 | -0.0172464 |
| GNAS | GNAS complex locus | -0.016746 |
| NOP58 | NOP58 ribonucleoprotein | -0.0167232 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0164707 |
| SGO2 | shugoshin 2 | -0.016439 |
| ATP13A3 | ATPase type 13A3 | -0.016413 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0163781 |
| MT2A | metallothionein 2A | -0.0156766 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.01557 |
| HELZ | helicase with zinc finger | -0.0154846 |
| FBXO42 | F-box protein 42 | -0.0152567 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.015121 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0150685 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0148705 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0148012 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0145868 |
| RPLP1 | ribosomal protein, large, P1 | -0.0144293 |
| HBP1 | HMG-box transcription factor 1 | -0.014418 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0143583 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0142804 |
| INSIG2 | insulin induced gene 2 | -0.0142776 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0141945 |
| RBM39 | RNA binding motif protein 39 | -0.0141573 |
| SBF2 | SET binding factor 2 | -0.0141473 |
| S100A6 | S100 calcium binding protein A6 | -0.0140437 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0140056 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0139448 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.0132667 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0132656 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.013102 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0130345 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0126969 |
| SUCO | SUN domain containing ossification factor | -0.01254 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0124442 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0123748 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.012343 |
| CENPE | centromere protein E, 312kDa | -0.0123253 |
| RYBP | RING1 and YY1 binding protein | -0.0123074 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0122261 |
| FOXO3 | forkhead box O3 | -0.0121186 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0120367 |
| RPL35A | ribosomal protein L35a | -0.0119402 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0118494 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0117971 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0117947 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.0116717 |
| IRS2 | insulin receptor substrate 2 | -0.0115231 |
| TTK | TTK protein kinase | -0.0114871 |
| CDC73 | cell division cycle 73 | -0.0114787 |
| DUSP6 | dual specificity phosphatase 6 | -0.0114631 |
| CENPF | centromere protein F, 350/400kDa | -0.0114579 |
| HDAC3 | histone deacetylase 3 | -0.0112379 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0112018 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0111435 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0111409 |
