| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.165816 |
| EXT1 | exostosin glycosyltransferase 1 | 0.15652 |
| SMAD3 | SMAD family member 3 | 0.147895 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0708583 |
| NTN4 | netrin 4 | 0.0699727 |
| INTS6 | integrator complex subunit 6 | 0.068041 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0676339 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0673779 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0662545 |
| ATXN1 | ataxin 1 | 0.0656591 |
| NDRG1 | N-myc downstream regulated 1 | 0.0649848 |
| TJP1 | tight junction protein 1 | 0.064353 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0588875 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0522767 |
| PLEC | plectin | 0.0516946 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0512401 |
| KRT8 | keratin 8, type II | 0.0511993 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0511458 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0509953 |
| DST | dystonin | 0.050491 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.050421 |
| CTBP2 | C-terminal binding protein 2 | 0.047587 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0472175 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0465772 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0464913 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0461593 |
| ANXA11 | annexin A11 | 0.0452599 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0437246 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0428571 |
| FAT1 | FAT atypical cadherin 1 | 0.0421522 |
| TLE4 | transducin-like enhancer of split 4 | 0.0413547 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0396329 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0390677 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0385216 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0384058 |
| RNF213 | ring finger protein 213 | 0.0382326 |
| MYOF | myoferlin | 0.0379718 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0376954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0372961 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0370628 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0364449 |
| TMEM123 | transmembrane protein 123 | 0.0350855 |
| VEGFA | vascular endothelial growth factor A | 0.0343886 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336872 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0333112 |
| PRR5L | proline rich 5 like | 0.0329115 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0322922 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.032024 |
| AXIN2 | axin 2 | 0.031701 |
| CCNYL1 | cyclin Y-like 1 | 0.0316712 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.031268 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0310419 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.030916 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294752 |
| EXPH5 | exophilin 5 | 0.0292647 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0291627 |
| KRT18 | keratin 18, type I | 0.0287117 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.02729 |
| MYO5B | myosin VB | 0.0266542 |
| MYO1E | myosin IE | 0.0265589 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0265229 |
| PLK2 | polo-like kinase 2 | 0.0264954 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0263593 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0255624 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252393 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0251463 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0246017 |
| MYZAP | myocardial zonula adherens protein | 0.0241629 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0240787 |
| ETV6 | ets variant 6 | 0.0239092 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0236402 |
| SGMS2 | sphingomyelin synthase 2 | 0.0236326 |
| WLS | wntless Wnt ligand secretion mediator | 0.0235858 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0228479 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0227058 |
| SIK3 | SIK family kinase 3 | 0.0222813 |
| GLCCI1 | glucocorticoid induced 1 | 0.0222662 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0222658 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0221949 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0220315 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0219108 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0218207 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0213981 |
| CDK6 | cyclin-dependent kinase 6 | 0.0211809 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0210567 |
| FLNB | filamin B, beta | 0.020958 |
| TUFT1 | tuftelin 1 | 0.0208725 |
| TMC5 | transmembrane channel-like 5 | 0.0206817 |
| MYO18A | myosin XVIIIA | 0.0206157 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0203378 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0202639 |
| SEPTIN9 | septin 9 | 0.0201956 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0201737 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0201701 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0201166 |
| PDE10A | phosphodiesterase 10A | 0.0200577 |
| PDZD8 | PDZ domain containing 8 | 0.0200391 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0200262 |
| VCL | vinculin | 0.0198548 |
| SERTAD2 | SERTA domain containing 2 | 0.0198442 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.114878 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104746 |
| PTMA | prothymosin, alpha | -0.0951651 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572674 |
| RPS6 | ribosomal protein S6 | -0.0497783 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0458195 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0455269 |
| RPLP1 | ribosomal protein, large, P1 | -0.0453447 |
| LYZ | lysozyme | -0.0448819 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0437552 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0426595 |
| AHNAK | AHNAK nucleoprotein | -0.0418314 |
| S100A6 | S100 calcium binding protein A6 | -0.039427 |
| RPS24 | ribosomal protein S24 | -0.0392292 |
| GOLGA4 | golgin A4 | -0.0391711 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0390905 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0367257 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0365571 |
| AGR2 | anterior gradient 2 | -0.0364294 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0350061 |
| RPL23 | ribosomal protein L23 | -0.0344529 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0329709 |
| RPS19 | ribosomal protein S19 | -0.0316611 |
| WASF2 | WAS protein family, member 2 | -0.0315332 |
| ANXA2 | annexin A2 | -0.031417 |
| TMSB10 | thymosin beta 10 | -0.0313507 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0309233 |
| LDHA | lactate dehydrogenase A | -0.0298814 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0288778 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0288077 |
| RPL12 | ribosomal protein L12 | -0.0279686 |
| RPL34 | ribosomal protein L34 | -0.0277865 |
| SDC4 | syndecan 4 | -0.0271698 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0269582 |
| SQSTM1 | sequestosome 1 | -0.0264499 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.026197 |
| TES | testin LIM domain protein | -0.0260842 |
| RTN4 | reticulon 4 | -0.0257397 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255461 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0254866 |
| HM13 | histocompatibility (minor) 13 | -0.0253781 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0251817 |
| CANX | calnexin | -0.0250398 |
| RPL35A | ribosomal protein L35a | -0.0247533 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0246154 |
| RPS16 | ribosomal protein S16 | -0.024256 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0236226 |
| EZR | ezrin | -0.0236183 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0233026 |
| RPL13A | ribosomal protein L13a | -0.0232071 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228641 |
| RTN3 | reticulon 3 | -0.0225592 |
| RPS11 | ribosomal protein S11 | -0.0219248 |
| HDLBP | high density lipoprotein binding protein | -0.0214393 |
| S100A10 | S100 calcium binding protein A10 | -0.0213778 |
| PGK1 | phosphoglycerate kinase 1 | -0.021077 |
| RPL27A | ribosomal protein L27a | -0.021067 |
| RPLP2 | ribosomal protein, large, P2 | -0.0210187 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0208888 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0205294 |
| LAMA4 | laminin, alpha 4 | -0.0203521 |
| HMGB1 | high mobility group box 1 | -0.0201587 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.02014 |
| RPL4 | ribosomal protein L4 | -0.020081 |
| HMGA1 | high mobility group AT-hook 1 | -0.0198563 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0198348 |
| FTL | ferritin, light polypeptide | -0.0196989 |
| RPS5 | ribosomal protein S5 | -0.0195852 |
| RRBP1 | ribosome binding protein 1 | -0.0194936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0190778 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.018976 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0188437 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.018716 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0185972 |
| RPS8 | ribosomal protein S8 | -0.0185742 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0183375 |
| KRT20 | keratin 20, type I | -0.018266 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0181538 |
| MMP7 | matrix metallopeptidase 7 | -0.0181363 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0181106 |
| RPS21 | ribosomal protein S21 | -0.0180772 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.017806 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0176024 |
| CALU | calumenin | -0.0175732 |
| ACTN4 | actinin, alpha 4 | -0.0175041 |
| MYL12B | myosin, light chain 12B, regulatory | -0.017497 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0173921 |
| ITGA6 | integrin, alpha 6 | -0.0173626 |
| COG5 | component of oligomeric golgi complex 5 | -0.017275 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0170338 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0170049 |
| PYGB | phosphorylase, glycogen; brain | -0.0169411 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0167929 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0167491 |
| CENPF | centromere protein F, 350/400kDa | -0.016593 |
| POMP | proteasome maturation protein | -0.0164056 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0162239 |
| MAP4 | microtubule-associated protein 4 | -0.0161945 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0160734 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0159966 |
