| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLEC | plectin | 0.16095 |
| AOPEP | aminopeptidase O (putative) | 0.11058 |
| LMO7 | LIM domain 7 | 0.110155 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.109593 |
| MYOF | myoferlin | 0.10747 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0882315 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0727658 |
| TGM2 | transglutaminase 2 | 0.0715265 |
| RAI14 | retinoic acid induced 14 | 0.0630254 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0583952 |
| DOK5 | docking protein 5 | 0.0556588 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0550431 |
| PODXL | podocalyxin-like | 0.0533647 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0530937 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0524563 |
| DST | dystonin | 0.0491864 |
| KRT6A | keratin 6A, type II | 0.0471763 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0452556 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0446123 |
| SMAD3 | SMAD family member 3 | 0.0440614 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0436125 |
| ADAR | adenosine deaminase, RNA-specific | 0.0431553 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0428076 |
| FN1 | fibronectin 1 | 0.0426633 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0421522 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0417928 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0408985 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0405378 |
| FLNA | filamin A, alpha | 0.0401084 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0399397 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0395823 |
| PRRC2C | proline-rich coiled-coil 2C | 0.03934 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0389568 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0380562 |
| SEPTIN9 | septin 9 | 0.037833 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0367579 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0364914 |
| JAG1 | jagged 1 | 0.0358781 |
| PRELID2 | PRELI domain containing 2 | 0.0354659 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342385 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0333094 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0332807 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.033196 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0329236 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0319535 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0319474 |
| CUL4B | cullin 4B | 0.0318142 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0313268 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.031059 |
| CEP250 | centrosomal protein 250kDa | 0.0307212 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0304439 |
| SULF1 | sulfatase 1 | 0.0300892 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0290665 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.028991 |
| LAMA5 | laminin, alpha 5 | 0.0287976 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0282381 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0279881 |
| FAT1 | FAT atypical cadherin 1 | 0.0277701 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0277019 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0272482 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0272332 |
| RPL3 | ribosomal protein L3 | 0.0271276 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.027126 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0267806 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0267519 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0262516 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0261984 |
| VEGFA | vascular endothelial growth factor A | 0.0254028 |
| NONO | non-POU domain containing, octamer-binding | 0.0252257 |
| HLA-B | major histocompatibility complex, class I, B | 0.0252068 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0247218 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0247122 |
| IL6ST | interleukin 6 signal transducer | 0.0246878 |
| MXRA5 | matrix-remodelling associated 5 | 0.0246777 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0245852 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0244991 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0244004 |
| SFTPA2 | surfactant protein A2 | 0.0238332 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0238156 |
| FRMD5 | FERM domain containing 5 | 0.0238073 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0236585 |
| GBP4 | guanylate binding protein 4 | 0.0236495 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0235804 |
| ARRDC3 | arrestin domain containing 3 | 0.023517 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0234235 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0233171 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0232193 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0231225 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0230815 |
| ITGB8 | integrin, beta 8 | 0.0228243 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0227998 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0226651 |
| FNIP1 | folliculin interacting protein 1 | 0.0226234 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0225233 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0222672 |
| BARX2 | BARX homeobox 2 | 0.0221928 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.022189 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0220781 |
| MX1 | MX dynamin-like GTPase 1 | 0.0218675 |
| APP | amyloid beta (A4) precursor protein | 0.0216316 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.254463 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.16904 |
| FLNB | filamin B, beta | -0.0926662 |
| TMSB10 | thymosin beta 10 | -0.0693561 |
| EMP1 | epithelial membrane protein 1 | -0.0598176 |
| PTMA | prothymosin, alpha | -0.0584211 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0565664 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0555424 |
| ITGA6 | integrin, alpha 6 | -0.0496422 |
| GNAS | GNAS complex locus | -0.04806 |
| S100A10 | S100 calcium binding protein A10 | -0.0476666 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.044673 |
| EZR | ezrin | -0.0441703 |
| RPS21 | ribosomal protein S21 | -0.0431289 |
| LAMC2 | laminin, gamma 2 | -0.0398016 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0390593 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0385841 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0384994 |
| EGR1 | early growth response 1 | -0.0372906 |
| AHNAK | AHNAK nucleoprotein | -0.0367589 |
| NDRG1 | N-myc downstream regulated 1 | -0.0361291 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0358762 |
| HM13 | histocompatibility (minor) 13 | -0.034717 |
| POTEF | POTE ankyrin domain family, member F | -0.0342191 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0333273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0330943 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.032646 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0320625 |
| S100A2 | S100 calcium binding protein A2 | -0.031569 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0308818 |
| SPAG9 | sperm associated antigen 9 | -0.0306333 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0302647 |
| PALLD | palladin, cytoskeletal associated protein | -0.0300476 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0297654 |
| RBM39 | RNA binding motif protein 39 | -0.0297551 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.029692 |
| GOLGA4 | golgin A4 | -0.0296814 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0292162 |
| S100A6 | S100 calcium binding protein A6 | -0.0285955 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0285612 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0284639 |
| RPS6 | ribosomal protein S6 | -0.028368 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0278768 |
| DUSP5 | dual specificity phosphatase 5 | -0.0276133 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273329 |
| WASF2 | WAS protein family, member 2 | -0.0271382 |
| MYO10 | myosin X | -0.0268714 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0261284 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0260224 |
| DIAPH3 | diaphanous-related formin 3 | -0.0255807 |
| FOSL1 | FOS-like antigen 1 | -0.0254781 |
| RCOR1 | REST corepressor 1 | -0.025129 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0249966 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0249656 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0245627 |
| SRP54 | signal recognition particle 54kDa | -0.0241504 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0240444 |
| BCL2L1 | BCL2-like 1 | -0.0238522 |
| RTN4 | reticulon 4 | -0.0236319 |
| RPS24 | ribosomal protein S24 | -0.0235049 |
| COG5 | component of oligomeric golgi complex 5 | -0.023468 |
| S100A11 | S100 calcium binding protein A11 | -0.023394 |
| LDLR | low density lipoprotein receptor | -0.0233508 |
| CMIP | c-Maf inducing protein | -0.0233078 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0232558 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0231581 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0231381 |
| BSG | basigin (Ok blood group) | -0.0231182 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0229098 |
| S100A9 | S100 calcium binding protein A9 | -0.0227872 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227473 |
| RPLP1 | ribosomal protein, large, P1 | -0.0226092 |
| PTHLH | parathyroid hormone-like hormone | -0.0225597 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0225509 |
| KIAA0040 | KIAA0040 | -0.0222387 |
| TPM4 | tropomyosin 4 | -0.021997 |
| FOXO3 | forkhead box O3 | -0.0218904 |
| CD9 | CD9 molecule | -0.0218844 |
| LMNA | lamin A/C | -0.0215753 |
| LMAN1 | lectin, mannose-binding, 1 | -0.021531 |
| CD99 | CD99 molecule | -0.0213205 |
| DUSP6 | dual specificity phosphatase 6 | -0.0210254 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0207904 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0206274 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0205416 |
| KISS1 | KiSS-1 metastasis-suppressor | -0.0205312 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0202774 |
| JMJD1C | jumonji domain containing 1C | -0.020226 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0200086 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0199488 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0199228 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.01992 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.0199162 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0198561 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0198335 |
| SBF2 | SET binding factor 2 | -0.0197816 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0197059 |
| ANXA2 | annexin A2 | -0.0196765 |
| GLG1 | golgi glycoprotein 1 | -0.0195399 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0192687 |
