| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.158817 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.135216 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.120126 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.118504 |
| MYOF | myoferlin | 0.111513 |
| GDA | guanine deaminase | 0.0910724 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0857434 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0773923 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0763523 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0730596 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0721086 |
| HSPA8 | heat shock 70kDa protein 8 | 0.070601 |
| DSPP | dentin sialophosphoprotein | 0.0703295 |
| PLEC | plectin | 0.0699505 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0683374 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0616173 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0598348 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0592394 |
| VEGFA | vascular endothelial growth factor A | 0.0584595 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0515938 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0499643 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0495307 |
| RUNX1 | runt-related transcription factor 1 | 0.0494754 |
| SMAD3 | SMAD family member 3 | 0.0491924 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0479844 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0466884 |
| CMIP | c-Maf inducing protein | 0.0451469 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0449345 |
| SEPTIN9 | septin 9 | 0.0442787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.043475 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0429832 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0416106 |
| RNF213 | ring finger protein 213 | 0.0414762 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0405485 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0397363 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0389566 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0369672 |
| TJP1 | tight junction protein 1 | 0.0368788 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0367366 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0360736 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0359833 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0356131 |
| CREBBP | CREB binding protein | 0.0352326 |
| INTS6 | integrator complex subunit 6 | 0.0350049 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0345236 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0342814 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0334373 |
| ATXN1 | ataxin 1 | 0.033049 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0330435 |
| MB21D2 | Mab-21 domain containing 2 | 0.0321432 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0319569 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0317368 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0314278 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0305035 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0302931 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0299381 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0296895 |
| ANXA11 | annexin A11 | 0.0294822 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0294605 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0293212 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292552 |
| KLHL29 | kelch-like family member 29 | 0.0285878 |
| FNIP1 | folliculin interacting protein 1 | 0.0277523 |
| FLNA | filamin A, alpha | 0.0277264 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0276951 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0274885 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0274784 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0274292 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0272692 |
| DSTN | destrin (actin depolymerizing factor) | 0.0271939 |
| ATP11A | ATPase, class VI, type 11A | 0.0269468 |
| HDAC9 | histone deacetylase 9 | 0.0263743 |
| AOPEP | aminopeptidase O (putative) | 0.0263396 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0262921 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0260022 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258178 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0253783 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0253599 |
| DST | dystonin | 0.0253086 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0250505 |
| EFNB2 | ephrin-B2 | 0.0250138 |
| PMM2 | phosphomannomutase 2 | 0.0248725 |
| RBM47 | RNA binding motif protein 47 | 0.0247409 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0244662 |
| GOLGB1 | golgin B1 | 0.0243825 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0243721 |
| BRD2 | bromodomain containing 2 | 0.023976 |
| COBL | cordon-bleu WH2 repeat protein | 0.0237627 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0236472 |
| KRT17 | keratin 17, type I | 0.0235722 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0234624 |
| CTBP2 | C-terminal binding protein 2 | 0.0231037 |
| TMEM45B | transmembrane protein 45B | 0.0229349 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0229212 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.022515 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0225097 |
| TXNRD1 | thioredoxin reductase 1 | 0.0224982 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.022461 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0224419 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0223278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.267266 |
| TMSB10 | thymosin beta 10 | -0.148212 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.143708 |
| PTMA | prothymosin, alpha | -0.127121 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.116426 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0999333 |
| S100A6 | S100 calcium binding protein A6 | -0.0998666 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.097347 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0863212 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0823155 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0816587 |
| EHBP1 | EH domain binding protein 1 | -0.0665753 |
| S100A10 | S100 calcium binding protein A10 | -0.063015 |
| ITGA6 | integrin, alpha 6 | -0.0605402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0591144 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0580309 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0547001 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0518564 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0506592 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0502286 |
| POTEF | POTE ankyrin domain family, member F | -0.0488408 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0441946 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0440742 |
| RPS6 | ribosomal protein S6 | -0.0427612 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0424885 |
| S100A11 | S100 calcium binding protein A11 | -0.0423625 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0423428 |
| BCL2L1 | BCL2-like 1 | -0.0419621 |
| EMP1 | epithelial membrane protein 1 | -0.039079 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0387537 |
| RPLP1 | ribosomal protein, large, P1 | -0.0386305 |
| EPCAM | epithelial cell adhesion molecule | -0.0377981 |
| S100A9 | S100 calcium binding protein A9 | -0.0376199 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0374575 |
| PRKCA | protein kinase C, alpha | -0.0360799 |
| H1-0 | H1.0 linker histone | -0.0348699 |
| SMC4 | structural maintenance of chromosomes 4 | -0.034804 |
| HLA-A | major histocompatibility complex, class I, A | -0.0344162 |
| GPX2 | glutathione peroxidase 2 | -0.0343964 |
| LYZ | lysozyme | -0.0343756 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0339134 |
| DEK | DEK proto-oncogene | -0.0337166 |
| ATF5 | activating transcription factor 5 | -0.0335587 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.033418 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0332115 |
| AHNAK | AHNAK nucleoprotein | -0.0329344 |
| RPS24 | ribosomal protein S24 | -0.0327371 |
| ANLN | anillin, actin binding protein | -0.0325063 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0323751 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0319939 |
| GNAS | GNAS complex locus | -0.0319898 |
| AGR2 | anterior gradient 2 | -0.0319036 |
| KLK10 | kallikrein-related peptidase 10 | -0.0317665 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0309713 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0305502 |
| RPL35A | ribosomal protein L35a | -0.0299415 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0297136 |
| CCND1 | cyclin D1 | -0.0294597 |
| RPS21 | ribosomal protein S21 | -0.0288798 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0288418 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0286269 |
| RNF43 | ring finger protein 43 | -0.0284297 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0279762 |
| WWC1 | WW and C2 domain containing 1 | -0.0277081 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0273061 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0272779 |
| HMGB1 | high mobility group box 1 | -0.0272484 |
| S100P | S100 calcium binding protein P | -0.0271974 |
| ITGB4 | integrin, beta 4 | -0.027161 |
| AUTS2 | autism susceptibility candidate 2 | -0.0270222 |
| KRT7 | keratin 7, type II | -0.0264917 |
| DIAPH3 | diaphanous-related formin 3 | -0.0264486 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0264269 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0262419 |
| CLDN7 | claudin 7 | -0.0261995 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0261342 |
| RPL34 | ribosomal protein L34 | -0.0261182 |
| KPNB1 | karyopherin (importin) beta 1 | -0.025946 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0257576 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0257518 |
| RBM25 | RNA binding motif protein 25 | -0.0256264 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0255414 |
| CBX3 | chromobox homolog 3 | -0.0243892 |
| TPM4 | tropomyosin 4 | -0.0242113 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0236915 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0230157 |
| ENO1 | enolase 1, (alpha) | -0.0227589 |
| INSIG1 | insulin induced gene 1 | -0.0226472 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0224964 |
| RPS25 | ribosomal protein S25 | -0.0223307 |
| RPS16 | ribosomal protein S16 | -0.0223038 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0222252 |
| HMGA1 | high mobility group AT-hook 1 | -0.0221722 |
| THOC2 | THO complex 2 | -0.0219849 |
| TFRC | transferrin receptor | -0.0218253 |
| RPS19 | ribosomal protein S19 | -0.0217954 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0214859 |
| TMEM123 | transmembrane protein 123 | -0.021467 |
| TUBA1B | tubulin, alpha 1b | -0.021318 |
| PGK1 | phosphoglycerate kinase 1 | -0.0212504 |
