| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.317491 |
| MYOF | myoferlin | 0.139074 |
| TXNRD1 | thioredoxin reductase 1 | 0.137775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1057 |
| LOC112694756 | uncharaterized LOC112694756 | 0.090581 |
| SLTM | SAFB-like, transcription modulator | 0.0895079 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0798005 |
| RNF213 | ring finger protein 213 | 0.0797829 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0788814 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0773592 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0766255 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0744869 |
| SMAD3 | SMAD family member 3 | 0.0731526 |
| GRAMD1B | GRAM domain containing 1B | 0.072995 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0727054 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0668409 |
| LMO7 | LIM domain 7 | 0.0629572 |
| PLEC | plectin | 0.0603044 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0588372 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0574328 |
| ENO1 | enolase 1, (alpha) | 0.0573851 |
| FAM13A | family with sequence similarity 13, member A | 0.0569359 |
| RUNX1 | runt-related transcription factor 1 | 0.0558235 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0557148 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0556569 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0551183 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0528275 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0509943 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0509048 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.050894 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0487979 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0474291 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460387 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0459953 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0459597 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0438191 |
| SMYD3 | SET and MYND domain containing 3 | 0.0431201 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0427925 |
| DSPP | dentin sialophosphoprotein | 0.0427516 |
| ANXA2 | annexin A2 | 0.042401 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0418168 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0414065 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0413739 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0412233 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0406708 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0406123 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0399857 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0398693 |
| KRT18 | keratin 18, type I | 0.0388305 |
| FAT1 | FAT atypical cadherin 1 | 0.038294 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0381124 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0377097 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.03629 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.036234 |
| RPS3 | ribosomal protein S3 | 0.0361627 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0357697 |
| LDHA | lactate dehydrogenase A | 0.0351169 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0349349 |
| GPHN | gephyrin | 0.0349108 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0346171 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0343672 |
| ARRDC3 | arrestin domain containing 3 | 0.0340664 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340624 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0337602 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0335435 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0334664 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0333069 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0331999 |
| APP | amyloid beta (A4) precursor protein | 0.0330179 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0326517 |
| DST | dystonin | 0.032358 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0320681 |
| ADAR | adenosine deaminase, RNA-specific | 0.0319255 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0317893 |
| STC2 | stanniocalcin 2 | 0.0313652 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0312684 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0311365 |
| ANO6 | anoctamin 6 | 0.0308457 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0306642 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0305854 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0301511 |
| YBX3 | Y box binding protein 3 | 0.0299389 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0294435 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0294359 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291423 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0291087 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0289019 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0288984 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0286661 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0285319 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0278868 |
| SPAG9 | sperm associated antigen 9 | 0.027853 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0278082 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0272122 |
| CANX | calnexin | 0.0270787 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0270418 |
| DTNA | dystrobrevin, alpha | 0.0268577 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0266557 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0265998 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0265577 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.116337 |
| EGR1 | early growth response 1 | -0.067491 |
| MCL1 | myeloid cell leukemia 1 | -0.063767 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0627391 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0435062 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.043382 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0429553 |
| NABP1 | nucleic acid binding protein 1 | -0.041948 |
| MT2A | metallothionein 2A | -0.0416363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.039018 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0362323 |
| RPS24 | ribosomal protein S24 | -0.0339503 |
| RPL35A | ribosomal protein L35a | -0.0301819 |
| PTMA | prothymosin, alpha | -0.0293803 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0274296 |
| CST3 | cystatin C | -0.0259894 |
| STC1 | stanniocalcin 1 | -0.0248702 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0247404 |
| RPL34 | ribosomal protein L34 | -0.0237148 |
| LAMA4 | laminin, alpha 4 | -0.02317 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0225651 |
| LAMC2 | laminin, gamma 2 | -0.0221976 |
| ACTG1 | actin gamma 1 | -0.0211511 |
| RIN2 | Ras and Rab interactor 2 | -0.0203183 |
| RSF1 | remodeling and spacing factor 1 | -0.0200215 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199416 |
| OSMR | oncostatin M receptor | -0.0199013 |
| AREG | amphiregulin | -0.0189673 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0188388 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0187949 |
| S100P | S100 calcium binding protein P | -0.0186213 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0185795 |
| ENSA | endosulfine alpha | -0.0179854 |
| SMIM14 | small integral membrane protein 14 | -0.0179739 |
| FBXO11 | F-box protein 11 | -0.0178234 |
| ARF4 | ADP-ribosylation factor 4 | -0.0175319 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0174348 |
| S100A6 | S100 calcium binding protein A6 | -0.0172368 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0170124 |
| CCNL1 | cyclin L1 | -0.0167141 |
| HLA-B | major histocompatibility complex, class I, B | -0.0166695 |
| GOLGB1 | golgin B1 | -0.0164394 |
| SYAP1 | synapse associated protein 1 | -0.0163784 |
| SDC4 | syndecan 4 | -0.0162915 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0161815 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0159765 |
| AGR2 | anterior gradient 2 | -0.0156645 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0154216 |
| VMP1 | vacuole membrane protein 1 | -0.0153711 |
| S100A9 | S100 calcium binding protein A9 | -0.0152072 |
| F11R | F11 receptor | -0.015112 |
| S100A11 | S100 calcium binding protein A11 | -0.0149199 |
| TMEM165 | transmembrane protein 165 | -0.0148723 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0148093 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0148002 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.014755 |
| HMGA1 | high mobility group AT-hook 1 | -0.0147126 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0145239 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0145211 |
| RPS29 | ribosomal protein S29 | -0.0145103 |
| RPL37 | ribosomal protein L37 | -0.0143255 |
| FRMD4B | FERM domain containing 4B | -0.0142627 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0141789 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0140652 |
| FRY | furry homolog (Drosophila) | -0.0140036 |
| RPS25 | ribosomal protein S25 | -0.013903 |
| RIOK3 | RIO kinase 3 | -0.0138606 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0138327 |
| IER3 | immediate early response 3 | -0.0135132 |
| RPLP1 | ribosomal protein, large, P1 | -0.0135043 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0135006 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0134992 |
| RPL31 | ribosomal protein L31 | -0.01336 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0132821 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0132318 |
| LRRC23 | leucine rich repeat containing 23 | -0.0131449 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0131244 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0129472 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0129139 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0127964 |
| RPS6 | ribosomal protein S6 | -0.0127578 |
| RPLP2 | ribosomal protein, large, P2 | -0.0127373 |
| SBF2 | SET binding factor 2 | -0.0125226 |
| SELENOS | selenoprotein S | -0.0124674 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0124475 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.0121318 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0121127 |
| MAGT1 | magnesium transporter 1 | -0.0120296 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0119606 |
| CD99 | CD99 molecule | -0.0119008 |
| DUSP5 | dual specificity phosphatase 5 | -0.0116488 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0114305 |
| PERP | PERP, TP53 apoptosis effector | -0.0114278 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.0113109 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.011228 |
| MORF4L2 | mortality factor 4 like 2 | -0.0111713 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0110806 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0109332 |
| RB1 | retinoblastoma 1 | -0.0108921 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0108758 |
