| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the TAK-733_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.123369 |
| VEGFA | vascular endothelial growth factor A | 0.0883069 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0765716 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0700035 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0646893 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0639593 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0625181 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0565654 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0505186 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0459471 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0456635 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0451496 |
| FAM20C | family with sequence similarity 20, member C | 0.0423791 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0410758 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403664 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0399033 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0385425 |
| PLEC | plectin | 0.0384229 |
| NAV2 | neuron navigator 2 | 0.0382554 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0381022 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.037156 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0371404 |
| KSR1 | kinase suppressor of ras 1 | 0.0368914 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0357355 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0345858 |
| SEPTIN9 | septin 9 | 0.0333917 |
| RUNX1 | runt-related transcription factor 1 | 0.0333823 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.033034 |
| LOXL2 | lysyl oxidase-like 2 | 0.0326003 |
| CEP250 | centrosomal protein 250kDa | 0.0323078 |
| SSH1 | slingshot protein phosphatase 1 | 0.0312276 |
| GATA6 | GATA binding protein 6 | 0.0303052 |
| TGM2 | transglutaminase 2 | 0.0300623 |
| LOC112694756 | uncharaterized LOC112694756 | 0.029124 |
| IL1R1 | interleukin 1 receptor, type I | 0.0291135 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0286843 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.0282519 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02815 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0280423 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0273619 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0272718 |
| NDRG1 | N-myc downstream regulated 1 | 0.0265444 |
| CD109 | CD109 molecule | 0.026505 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0263815 |
| NTN4 | netrin 4 | 0.0262104 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0260894 |
| RPL3 | ribosomal protein L3 | 0.0257392 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0255633 |
| MYO10 | myosin X | 0.0248392 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236624 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.023544 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0235327 |
| STC2 | stanniocalcin 2 | 0.0233292 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0228693 |
| SFTPA2 | surfactant protein A2 | 0.0217035 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0214641 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0214602 |
| E2F7 | E2F transcription factor 7 | 0.0214285 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0213893 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0213557 |
| MB21D2 | Mab-21 domain containing 2 | 0.0211116 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0201905 |
| B2M | beta-2-microglobulin | 0.0201808 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0201186 |
| APP | amyloid beta (A4) precursor protein | 0.0200134 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0199938 |
| FLNA | filamin A, alpha | 0.0199122 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0195457 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0195319 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0190455 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0188767 |
| ADAR | adenosine deaminase, RNA-specific | 0.0185544 |
| ANGPTL4 | angiopoietin-like 4 | 0.0184026 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0182989 |
| CTSC | cathepsin C | 0.0178955 |
| SMAP2 | small ArfGAP2 | 0.0178086 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0177795 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0176832 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0176043 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.0175782 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.017556 |
| GPATCH2L | G patch domain containing 2-like | 0.0172388 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0169427 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0168938 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.016876 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.016833 |
| INTS6 | integrator complex subunit 6 | 0.0167967 |
| FOSL1 | FOS-like antigen 1 | 0.0166574 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.016645 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0165647 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0165457 |
| ARRDC3 | arrestin domain containing 3 | 0.0164946 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0164382 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0164005 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.016368 |
| UPP1 | uridine phosphorylase 1 | 0.0163107 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0162159 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0162134 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0161602 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0161134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.147832 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.145217 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.125348 |
| VIM | vimentin | -0.11472 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0883504 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0857666 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0820124 |
| CDH13 | cadherin 13 | -0.080693 |
| HMGA2 | high mobility group AT-hook 2 | -0.0787134 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0714313 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0711204 |
| PTMA | prothymosin, alpha | -0.0703977 |
| OSMR | oncostatin M receptor | -0.0665739 |
| JMJD1C | jumonji domain containing 1C | -0.063122 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0593394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0577508 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0573922 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0562219 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0546887 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0514728 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0508416 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.050352 |
| RAI14 | retinoic acid induced 14 | -0.0492492 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0489187 |
| EFNA5 | ephrin-A5 | -0.0488372 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0488215 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0486377 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0484701 |
| RPLP1 | ribosomal protein, large, P1 | -0.0480292 |
| MTSS1 | metastasis suppressor 1 | -0.0465589 |
| S100A6 | S100 calcium binding protein A6 | -0.0458278 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.045153 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0444673 |
| GLCCI1 | glucocorticoid induced 1 | -0.0438207 |
| FTL | ferritin, light polypeptide | -0.0437476 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0430433 |
| NUMB | numb homolog (Drosophila) | -0.042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414417 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0413596 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0412752 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.04125 |
| RBM39 | RNA binding motif protein 39 | -0.0412446 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0407799 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0405256 |
| IER3 | immediate early response 3 | -0.0393425 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0386971 |
| MT2A | metallothionein 2A | -0.0382624 |
| STC1 | stanniocalcin 1 | -0.0367336 |
| PARD3 | par-3 family cell polarity regulator | -0.0366428 |
| VMP1 | vacuole membrane protein 1 | -0.0364002 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0362392 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.035027 |
| USP34 | ubiquitin specific peptidase 34 | -0.035008 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0345878 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0345754 |
| RPS24 | ribosomal protein S24 | -0.0344652 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0341007 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0338541 |
| RPS19 | ribosomal protein S19 | -0.0338319 |
| LOX | lysyl oxidase | -0.0335676 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0333784 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0332928 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0328562 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0326824 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0321625 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0321451 |
| FBXO11 | F-box protein 11 | -0.0319489 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0318781 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0314918 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0314587 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0314129 |
| OXR1 | oxidation resistance 1 | -0.0313131 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0298177 |
| AHNAK | AHNAK nucleoprotein | -0.0296573 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284553 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0284068 |
| BMERB1 | bMERB domain containing 1 | -0.0282498 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.028092 |
| FN1 | fibronectin 1 | -0.0279315 |
| PRR16 | proline rich 16 | -0.0275949 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0273894 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0273145 |
| PRRX1 | paired related homeobox 1 | -0.0270153 |
| RPL35A | ribosomal protein L35a | -0.0267742 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0266479 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0263121 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0252113 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0251502 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0250708 |
| TMEM165 | transmembrane protein 165 | -0.0250206 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0245026 |
| SPAG9 | sperm associated antigen 9 | -0.0241062 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0239512 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0239426 |
| GNAS | GNAS complex locus | -0.0238133 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0236308 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0235941 |
| GPC6 | glypican 6 | -0.0233243 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.0232514 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0231693 |
