| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.123688 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.100399 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.088173 |
| LAMB3 | laminin, beta 3 | 0.0756582 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0739405 |
| ANXA2 | annexin A2 | 0.072896 |
| KRT17 | keratin 17, type I | 0.0678286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0583535 |
| ACTN4 | actinin, alpha 4 | 0.056374 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0538276 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0536192 |
| MED13 | mediator complex subunit 13 | 0.0516519 |
| TJP1 | tight junction protein 1 | 0.0508497 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0507744 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0498525 |
| PLEC | plectin | 0.0495686 |
| MXD1 | MAX dimerization protein 1 | 0.0488122 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0487433 |
| KYNU | kynureninase | 0.0464555 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0462972 |
| FAT1 | FAT atypical cadherin 1 | 0.0445824 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0435338 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.041748 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0415927 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0408508 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0407134 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.039857 |
| ANXA1 | annexin A1 | 0.0393257 |
| LAMC2 | laminin, gamma 2 | 0.0393219 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0390541 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0385534 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385126 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0377734 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0372999 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0366489 |
| EZR | ezrin | 0.0365668 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0357444 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0349695 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0347982 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0347653 |
| MYO5B | myosin VB | 0.0337817 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0333615 |
| ZNF292 | zinc finger protein 292 | 0.0330361 |
| TXNRD1 | thioredoxin reductase 1 | 0.033011 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0323728 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0322972 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0321815 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0320917 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0318927 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0316953 |
| CANX | calnexin | 0.0315335 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0309797 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0308074 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0306232 |
| NCKAP1 | NCK-associated protein 1 | 0.0298636 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0290523 |
| MCL1 | myeloid cell leukemia 1 | 0.0288975 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0288151 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0287795 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0283007 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0282446 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0282247 |
| AHNAK | AHNAK nucleoprotein | 0.0278478 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0268726 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0267162 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0260335 |
| CALU | calumenin | 0.0259785 |
| HDLBP | high density lipoprotein binding protein | 0.025946 |
| TNNC1 | troponin C type 1 (slow) | 0.0257862 |
| NEBL | nebulette | 0.0257123 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0256388 |
| CPNE8 | copine VIII | 0.0255638 |
| STC2 | stanniocalcin 2 | 0.0254908 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0253604 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0253424 |
| MYOF | myoferlin | 0.0250943 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0250538 |
| CTBP2 | C-terminal binding protein 2 | 0.0250017 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0245833 |
| VEGFA | vascular endothelial growth factor A | 0.024215 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0238793 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0238481 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0233984 |
| NDRG1 | N-myc downstream regulated 1 | 0.023337 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0233252 |
| CDCP1 | CUB domain containing protein 1 | 0.02316 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0231578 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0230732 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0230448 |
| KRT18 | keratin 18, type I | 0.0229831 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.022959 |
| SQSTM1 | sequestosome 1 | 0.0228393 |
| ANKRD17 | ankyrin repeat domain 17 | 0.022656 |
| PKM | pyruvate kinase, muscle | 0.0225927 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.022431 |
| FRMD5 | FERM domain containing 5 | 0.02227 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0222202 |
| TGFA | transforming growth factor, alpha | 0.0221063 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0221021 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0217326 |
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.084408 |
| TMSB10 | thymosin beta 10 | -0.0771874 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.074643 |
| MUC16 | mucin 16, cell surface associated | -0.0659818 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0604572 |
| S100A6 | S100 calcium binding protein A6 | -0.0570883 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.056499 |
| S100A9 | S100 calcium binding protein A9 | -0.0532561 |
| VIM | vimentin | -0.0521536 |
| RPS25 | ribosomal protein S25 | -0.0521282 |
| RPLP0 | ribosomal protein, large, P0 | -0.0521154 |
| TPM4 | tropomyosin 4 | -0.0516642 |
| RPS16 | ribosomal protein S16 | -0.0510761 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0458808 |
| ATOSA | atos homolog A | -0.0451747 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0442073 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0442047 |
| RPS6 | ribosomal protein S6 | -0.0437256 |
| POTEF | POTE ankyrin domain family, member F | -0.043674 |
| RPL35A | ribosomal protein L35a | -0.0416483 |
| HLA-B | major histocompatibility complex, class I, B | -0.0413807 |
| RIGI | RNA sensor RIG-I | -0.0410058 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0406655 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0405124 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0402919 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0379141 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0371936 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0369835 |
| HLA-A | major histocompatibility complex, class I, A | -0.035586 |
| RHOA | ras homolog family member A | -0.0351601 |
| RPL37 | ribosomal protein L37 | -0.0343424 |
| CALD1 | caldesmon 1 | -0.0340377 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0337497 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0331248 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0330349 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0321689 |
| MT2A | metallothionein 2A | -0.0320882 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0319808 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0318008 |
| RPS24 | ribosomal protein S24 | -0.0315247 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0312095 |
| RPL15 | ribosomal protein L15 | -0.0311992 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0311835 |
| TMEM165 | transmembrane protein 165 | -0.0308059 |
| THOC2 | THO complex 2 | -0.0306876 |
| RSF1 | remodeling and spacing factor 1 | -0.0305892 |
| RPL34 | ribosomal protein L34 | -0.0304713 |
| COG6 | component of oligomeric golgi complex 6 | -0.0300596 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0299053 |
| RPS20 | ribosomal protein S20 | -0.0297463 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.029327 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0288026 |
| ERBIN | erbb2 interacting protein | -0.0287802 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.028437 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.027962 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0276182 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0271279 |
| KLHL24 | kelch-like family member 24 | -0.0269274 |
| SMYD3 | SET and MYND domain containing 3 | -0.0265213 |
| RCOR1 | REST corepressor 1 | -0.0261856 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.026007 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0258856 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.02585 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0256054 |
| JMJD1C | jumonji domain containing 1C | -0.02476 |
| HELZ | helicase with zinc finger | -0.024449 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0243828 |
| RPLP2 | ribosomal protein, large, P2 | -0.0242778 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0241736 |
| HDAC9 | histone deacetylase 9 | -0.0240542 |
| EFNA5 | ephrin-A5 | -0.0236083 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0234098 |
| RPL31 | ribosomal protein L31 | -0.0232519 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0231097 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0228716 |
| S100A11 | S100 calcium binding protein A11 | -0.0226294 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0225399 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0222434 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0219188 |
| ASTN2 | astrotactin 2 | -0.0219057 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0218404 |
| MEF2A | myocyte enhancer factor 2A | -0.0217801 |
| CXXC1 | CXXC finger protein 1 | -0.0217622 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0217604 |
| EHBP1 | EH domain binding protein 1 | -0.0217455 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0217256 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0215063 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0214385 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0211537 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0211513 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.021034 |
| SRP54 | signal recognition particle 54kDa | -0.0209356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0208957 |
| STEAP4 | STEAP family member 4 | -0.020799 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0207178 |
| GPHN | gephyrin | -0.0206777 |
| RPS11 | ribosomal protein S11 | -0.0206157 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0205148 |
| GOLGA2 | golgin A2 | -0.020403 |
| CD44 | CD44 molecule (Indian blood group) | -0.0203049 |
