| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.259413 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.197487 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.167248 |
| PLEC | plectin | 0.140044 |
| EXT1 | exostosin glycosyltransferase 1 | 0.129775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.125962 |
| NDRG1 | N-myc downstream regulated 1 | 0.119447 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105672 |
| VEGFA | vascular endothelial growth factor A | 0.0926569 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0915898 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0813977 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0772652 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0758842 |
| HSPA8 | heat shock 70kDa protein 8 | 0.070084 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0692495 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0677484 |
| LAMC2 | laminin, gamma 2 | 0.0645706 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0629203 |
| ARRDC3 | arrestin domain containing 3 | 0.0623736 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0619847 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0588814 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0588757 |
| RUNX1 | runt-related transcription factor 1 | 0.0558664 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0540837 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0530488 |
| NAV2 | neuron navigator 2 | 0.0523892 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0519642 |
| SMAD3 | SMAD family member 3 | 0.0514667 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0513312 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0500997 |
| BRD2 | bromodomain containing 2 | 0.0500104 |
| FLNA | filamin A, alpha | 0.0495528 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0494556 |
| MSN | moesin | 0.0489614 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.048547 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0483115 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0471832 |
| DSPP | dentin sialophosphoprotein | 0.0465008 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0448 |
| APP | amyloid beta (A4) precursor protein | 0.0442609 |
| CD109 | CD109 molecule | 0.0440378 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0436202 |
| KIAA1217 | KIAA1217 | 0.04357 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0428455 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0426215 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0407528 |
| MYOF | myoferlin | 0.0390842 |
| FLNB | filamin B, beta | 0.0382188 |
| FHIT | fragile histidine triad | 0.0378662 |
| ANXA2 | annexin A2 | 0.0376737 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0372939 |
| TPM3 | tropomyosin 3 | 0.037225 |
| SGMS2 | sphingomyelin synthase 2 | 0.037004 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364269 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.03581 |
| IL6ST | interleukin 6 signal transducer | 0.0354197 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0353713 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0352333 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0351751 |
| SQSTM1 | sequestosome 1 | 0.0339585 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0338485 |
| RPL3 | ribosomal protein L3 | 0.0336755 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0336351 |
| TXNRD1 | thioredoxin reductase 1 | 0.0335748 |
| ADAR | adenosine deaminase, RNA-specific | 0.0335347 |
| CTSB | cathepsin B | 0.0334335 |
| PKM | pyruvate kinase, muscle | 0.0333448 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0332324 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0328312 |
| PALLD | palladin, cytoskeletal associated protein | 0.0327572 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0327332 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0325437 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0324129 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0323446 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0320082 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0319827 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0313071 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0310696 |
| CTBP2 | C-terminal binding protein 2 | 0.0309354 |
| SEPTIN9 | septin 9 | 0.0308367 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0304868 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0301949 |
| PTK2 | protein tyrosine kinase 2 | 0.0301317 |
| EGR1 | early growth response 1 | 0.0300401 |
| CD44 | CD44 molecule (Indian blood group) | 0.0299947 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0299873 |
| INTS6 | integrator complex subunit 6 | 0.0298528 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0294018 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.029133 |
| DST | dystonin | 0.0291061 |
| KRT8 | keratin 8, type II | 0.0290957 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0282915 |
| GRAMD2B | GRAM domain containing 2B | 0.0281557 |
| TJP1 | tight junction protein 1 | 0.0279792 |
| GPC6 | glypican 6 | 0.02759 |
| CANX | calnexin | 0.0274353 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0274112 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0272405 |
| TUFT1 | tuftelin 1 | 0.026991 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0268589 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.141847 |
| TMSB10 | thymosin beta 10 | -0.121306 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.106194 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0886335 |
| S100A6 | S100 calcium binding protein A6 | -0.0723289 |
| FTL | ferritin, light polypeptide | -0.0638264 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0518899 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0491386 |
| CSTB | cystatin B (stefin B) | -0.045668 |
| CCND1 | cyclin D1 | -0.0455585 |
| RPL35A | ribosomal protein L35a | -0.0449035 |
| RPL34 | ribosomal protein L34 | -0.0439495 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0435447 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0429424 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.041878 |
| CD2AP | CD2-associated protein | -0.0391443 |
| TOP1 | topoisomerase (DNA) I | -0.0391342 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0389682 |
| FAM3C | family with sequence similarity 3, member C | -0.0386151 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0379477 |
| RPLP1 | ribosomal protein, large, P1 | -0.036626 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0348773 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0341871 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334385 |
| RPS24 | ribosomal protein S24 | -0.0331997 |
| GNAS | GNAS complex locus | -0.0317822 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0315887 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0310597 |
| PGK1 | phosphoglycerate kinase 1 | -0.0308051 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0303284 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302822 |
| FAM162A | family with sequence similarity 162, member A | -0.0301206 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0291574 |
| AHNAK | AHNAK nucleoprotein | -0.0291287 |
| HMGA1 | high mobility group AT-hook 1 | -0.0290779 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0285891 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0283155 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0281601 |
| S100A10 | S100 calcium binding protein A10 | -0.0274328 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0273784 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0264688 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0263253 |
| TPM4 | tropomyosin 4 | -0.0257411 |
| RPS6 | ribosomal protein S6 | -0.0256878 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0250796 |
| RPS21 | ribosomal protein S21 | -0.0247218 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0242693 |
| TMEM165 | transmembrane protein 165 | -0.0242462 |
| CTSD | cathepsin D | -0.0237181 |
| TMEM123 | transmembrane protein 123 | -0.023607 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.023352 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0231958 |
| VIM | vimentin | -0.0229649 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0226439 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0217435 |
| RPL31 | ribosomal protein L31 | -0.0217142 |
| S100A9 | S100 calcium binding protein A9 | -0.0214702 |
| HLA-A | major histocompatibility complex, class I, A | -0.0213258 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0213091 |
| EPCAM | epithelial cell adhesion molecule | -0.0206498 |
| RIOK3 | RIO kinase 3 | -0.0205465 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.020335 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0199146 |
| RPL12 | ribosomal protein L12 | -0.0193988 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0193857 |
| RBM25 | RNA binding motif protein 25 | -0.0192378 |
| RPS19 | ribosomal protein S19 | -0.0189663 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0187485 |
| RPS29 | ribosomal protein S29 | -0.0185417 |
| RPS25 | ribosomal protein S25 | -0.0185302 |
| RPS16 | ribosomal protein S16 | -0.0182985 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0182533 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0180899 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0180656 |
| S100A11 | S100 calcium binding protein A11 | -0.018054 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0175973 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0175958 |
| F11R | F11 receptor | -0.0175834 |
| RPS14 | ribosomal protein S14 | -0.0175026 |
| RPL27A | ribosomal protein L27a | -0.0174024 |
| RPL8 | ribosomal protein L8 | -0.0173823 |
| RPL26 | ribosomal protein L26 | -0.0173238 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0171038 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0168973 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0166231 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0165647 |
| RPL32 | ribosomal protein L32 | -0.0163173 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0159405 |
| RTN4 | reticulon 4 | -0.0158773 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0157528 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0154381 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0154025 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0152983 |
| RPL23 | ribosomal protein L23 | -0.0152564 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0152503 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0152467 |
| RPS23 | ribosomal protein S23 | -0.0152057 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.015195 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0151324 |
