| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.162345 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.139863 |
| MYOF | myoferlin | 0.123027 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0946766 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0940587 |
| GDA | guanine deaminase | 0.0889331 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0887809 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0857993 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0844669 |
| DST | dystonin | 0.0825707 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0823976 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0807299 |
| TXNRD1 | thioredoxin reductase 1 | 0.0788674 |
| CD109 | CD109 molecule | 0.0725978 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0705267 |
| STC2 | stanniocalcin 2 | 0.067465 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0672278 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0643463 |
| TBXT | T-box transcription factor T | 0.0626556 |
| FLNB | filamin B, beta | 0.0591464 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0580955 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0576419 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0565845 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0537803 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0529329 |
| ASPH | aspartate beta-hydroxylase | 0.0525224 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0507543 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0499517 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0482396 |
| MB21D2 | Mab-21 domain containing 2 | 0.0482032 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.048109 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0474149 |
| LAMA1 | laminin, alpha 1 | 0.0472605 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0456971 |
| ANXA2 | annexin A2 | 0.045408 |
| RUNX1 | runt-related transcription factor 1 | 0.0450815 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0450381 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0434172 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0434123 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0431794 |
| FLNA | filamin A, alpha | 0.0428138 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0427474 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0424516 |
| GRAMD1B | GRAM domain containing 1B | 0.042294 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.041524 |
| NDRG1 | N-myc downstream regulated 1 | 0.0415175 |
| FMNL2 | formin-like 2 | 0.0414486 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0401745 |
| KYNU | kynureninase | 0.0401175 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0400351 |
| RPL3 | ribosomal protein L3 | 0.0396501 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0396237 |
| COL5A2 | collagen, type V, alpha 2 | 0.0391636 |
| ATXN1 | ataxin 1 | 0.0385314 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0377565 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0372217 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.037064 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0366386 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0364173 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0355373 |
| SFTPA2 | surfactant protein A2 | 0.0351815 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0349131 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0346375 |
| PTEN | phosphatase and tensin homolog | 0.0345932 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0345722 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0344238 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0344072 |
| CANX | calnexin | 0.0341672 |
| NONO | non-POU domain containing, octamer-binding | 0.0337596 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0336291 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0329195 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0326166 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0324844 |
| LDHA | lactate dehydrogenase A | 0.0320531 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0317363 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0311099 |
| SMAD2 | SMAD family member 2 | 0.0309052 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0303062 |
| MSN | moesin | 0.0300713 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0297532 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.029572 |
| CTBP2 | C-terminal binding protein 2 | 0.0294546 |
| MAP7 | microtubule-associated protein 7 | 0.0294006 |
| SEPTIN9 | septin 9 | 0.0292012 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0280223 |
| FAT1 | FAT atypical cadherin 1 | 0.0278865 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0274126 |
| PLEC | plectin | 0.0270091 |
| SET | SET nuclear proto-oncogene | 0.0269776 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0269546 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0269138 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0266442 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0263669 |
| ALPK2 | alpha-kinase 2 | 0.0261294 |
| ABLIM1 | actin binding LIM protein 1 | 0.025765 |
| GLCCI1 | glucocorticoid induced 1 | 0.0254514 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0253801 |
| OLFML2A | olfactomedin-like 2A | 0.0252244 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0251893 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0246833 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.284678 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.166297 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0736895 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0722385 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0706472 |
| EFNA5 | ephrin-A5 | -0.0671338 |
| PTMA | prothymosin, alpha | -0.0633723 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.06039 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0563718 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0538186 |
| TMSB10 | thymosin beta 10 | -0.0519899 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0484823 |
| RPS24 | ribosomal protein S24 | -0.0467259 |
| RPLP1 | ribosomal protein, large, P1 | -0.0459312 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0411122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0400034 |
| RPL35A | ribosomal protein L35a | -0.0390657 |
| VIM | vimentin | -0.0383912 |
| NCKAP5 | NCK-associated protein 5 | -0.0338565 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0330636 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0311363 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0304789 |
| RPS6 | ribosomal protein S6 | -0.0302434 |
| RPL37A | ribosomal protein L37a | -0.0287148 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0284571 |
| RPL31 | ribosomal protein L31 | -0.0277188 |
| RPL34 | ribosomal protein L34 | -0.0272813 |
| RPLP2 | ribosomal protein, large, P2 | -0.0251278 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0249627 |
| RPS19 | ribosomal protein S19 | -0.0244822 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0238798 |
| RPS27A | ribosomal protein S27a | -0.0238082 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0236312 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0236153 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0233927 |
| RPS29 | ribosomal protein S29 | -0.0233422 |
| TENM3 | teneurin transmembrane protein 3 | -0.0232533 |
| CDH13 | cadherin 13 | -0.0229684 |
| S100A6 | S100 calcium binding protein A6 | -0.0225192 |
| RIGI | RNA sensor RIG-I | -0.0219428 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0213924 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.021084 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0209933 |
| GNAS | GNAS complex locus | -0.0209439 |
| VCL | vinculin | -0.0205909 |
| KIAA0825 | KIAA0825 | -0.0204664 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0201639 |
| RPS21 | ribosomal protein S21 | -0.0200147 |
| RPL26 | ribosomal protein L26 | -0.0198198 |
| IL6 | interleukin 6 | -0.0196955 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0196458 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0194961 |
| FTL | ferritin, light polypeptide | -0.0193356 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0192251 |
| OSMR | oncostatin M receptor | -0.0190411 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0189757 |
| RPL12 | ribosomal protein L12 | -0.0189475 |
| RTN1 | reticulon 1 | -0.0188429 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0188206 |
| CCDC68 | coiled-coil domain containing 68 | -0.0179844 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0177606 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0176984 |
| PTGR1 | prostaglandin reductase 1 | -0.0176422 |
| RPS14 | ribosomal protein S14 | -0.0174582 |
| IER3 | immediate early response 3 | -0.0173015 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0172405 |
| RPL9 | ribosomal protein L9 | -0.0170977 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0169935 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0169466 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0168442 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0168229 |
| RPS16 | ribosomal protein S16 | -0.0164929 |
| RPL39 | ribosomal protein L39 | -0.016408 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0162631 |
| RPS23 | ribosomal protein S23 | -0.0160833 |
| RPS8 | ribosomal protein S8 | -0.015851 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0157941 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0157786 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.015744 |
| RPL38 | ribosomal protein L38 | -0.0156849 |
| PCDH15 | protocadherin-related 15 | -0.0156273 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0153925 |
| RPL37 | ribosomal protein L37 | -0.0153405 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0153069 |
| FN1 | fibronectin 1 | -0.0152244 |
| LSAMP | limbic system-associated membrane protein | -0.0151431 |
| PCDH9 | protocadherin 9 | -0.0150107 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0149562 |
| BMERB1 | bMERB domain containing 1 | -0.0145333 |
| PGM2L1 | phosphoglucomutase 2-like 1 | -0.0143052 |
| RPL13A | ribosomal protein L13a | -0.0142623 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0139078 |
| RPS28 | ribosomal protein S28 | -0.013809 |
| RPS11 | ribosomal protein S11 | -0.0136533 |
| RPS25 | ribosomal protein S25 | -0.0132665 |
| STC1 | stanniocalcin 1 | -0.0132128 |
| TPM4 | tropomyosin 4 | -0.0131817 |
| RPS15 | ribosomal protein S15 | -0.0131406 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0129921 |
| PRSS23 | protease, serine, 23 | -0.0129735 |
