| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.182606 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.130108 |
| SMAD3 | SMAD family member 3 | 0.116592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106246 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.102294 |
| PLEC | plectin | 0.0918786 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.091238 |
| VEGFA | vascular endothelial growth factor A | 0.0891002 |
| INTS6 | integrator complex subunit 6 | 0.0879601 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0849821 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0834455 |
| TJP1 | tight junction protein 1 | 0.0710999 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.070475 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.068712 |
| BRD2 | bromodomain containing 2 | 0.0666369 |
| KRT17 | keratin 17, type I | 0.0661619 |
| MYO5B | myosin VB | 0.0660259 |
| DSPP | dentin sialophosphoprotein | 0.0652163 |
| NAV2 | neuron navigator 2 | 0.0648099 |
| ARRDC3 | arrestin domain containing 3 | 0.0646603 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0643053 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0642003 |
| SQSTM1 | sequestosome 1 | 0.0635002 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0615078 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0603466 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0601928 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0568533 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0561146 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0529046 |
| SEPTIN9 | septin 9 | 0.0527957 |
| RACK1 | receptor for activated C kinase 1 | 0.0525793 |
| MUC16 | mucin 16, cell surface associated | 0.0525753 |
| RNF213 | ring finger protein 213 | 0.0525101 |
| FLNA | filamin A, alpha | 0.0517849 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0493412 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0493005 |
| MUC4 | mucin 4, cell surface associated | 0.0488762 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0478264 |
| KRT8 | keratin 8, type II | 0.0460252 |
| AFDN | afadin, adherens junction formation factor | 0.0459078 |
| ACTG1 | actin gamma 1 | 0.0457291 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0457091 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0452026 |
| KRT18 | keratin 18, type I | 0.0450723 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0445261 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0444407 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.044051 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0439804 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0437309 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0436141 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0426969 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0421369 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.041629 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0410004 |
| APP | amyloid beta (A4) precursor protein | 0.0404192 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0403112 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0401052 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0400812 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.038729 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0377778 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0375537 |
| ANXA11 | annexin A11 | 0.0370428 |
| CTBP2 | C-terminal binding protein 2 | 0.0367704 |
| MED15 | mediator complex subunit 15 | 0.0366346 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0365034 |
| MYO6 | myosin VI | 0.0358986 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.035827 |
| ATP11A | ATPase, class VI, type 11A | 0.0355919 |
| FAM107B | family with sequence similarity 107, member B | 0.0352295 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0350153 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0343306 |
| NDRG1 | N-myc downstream regulated 1 | 0.0342533 |
| ETV6 | ets variant 6 | 0.0337395 |
| CANX | calnexin | 0.0337376 |
| AMOTL2 | angiomotin like 2 | 0.0333272 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0332524 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0331272 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0328438 |
| SVIL | supervillin | 0.0321773 |
| PLAU | plasminogen activator, urokinase | 0.0316537 |
| IRS2 | insulin receptor substrate 2 | 0.0315944 |
| SIK3 | SIK family kinase 3 | 0.0311896 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0310395 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0308022 |
| EFNB2 | ephrin-B2 | 0.0307373 |
| SET | SET nuclear proto-oncogene | 0.0306925 |
| LAMB3 | laminin, beta 3 | 0.0306717 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0306396 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0304598 |
| FMNL2 | formin-like 2 | 0.0299658 |
| TLE4 | transducin-like enhancer of split 4 | 0.0299411 |
| FUS | FUS RNA binding protein | 0.0298704 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0296409 |
| HLA-B | major histocompatibility complex, class I, B | 0.0295395 |
| STC2 | stanniocalcin 2 | 0.0291677 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0291543 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.028824 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0288079 |
| ATF3 | activating transcription factor 3 | 0.0287887 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0287387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0930344 |
| PTMA | prothymosin, alpha | -0.08668 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.084653 |
| LAMA4 | laminin, alpha 4 | -0.0845042 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0741959 |
| CD2AP | CD2-associated protein | -0.0625122 |
| S100A6 | S100 calcium binding protein A6 | -0.0507667 |
| RPL35A | ribosomal protein L35a | -0.0503621 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0499238 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0458764 |
| PLAT | plasminogen activator, tissue | -0.0446338 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0423957 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0407043 |
| ASPH | aspartate beta-hydroxylase | -0.0406783 |
| FN1 | fibronectin 1 | -0.0387539 |
| KRT19 | keratin 19, type I | -0.0374252 |
| VCL | vinculin | -0.0373135 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0363265 |
| RPS24 | ribosomal protein S24 | -0.0360769 |
| DSG2 | desmoglein 2 | -0.0356375 |
| EMP1 | epithelial membrane protein 1 | -0.0356351 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349678 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.033222 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324748 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.031864 |
| ANLN | anillin, actin binding protein | -0.0308047 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0300064 |
| MT2A | metallothionein 2A | -0.0294549 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0292697 |
| HMGA1 | high mobility group AT-hook 1 | -0.0289959 |
| AHNAK | AHNAK nucleoprotein | -0.0285747 |
| RPL34 | ribosomal protein L34 | -0.027576 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0269705 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.026764 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026351 |
| TMEM123 | transmembrane protein 123 | -0.0260535 |
| OSMR | oncostatin M receptor | -0.0246326 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0244078 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.023947 |
| S100A11 | S100 calcium binding protein A11 | -0.0235109 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0230913 |
| DIAPH3 | diaphanous-related formin 3 | -0.0228777 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0228601 |
| EHBP1 | EH domain binding protein 1 | -0.0225143 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.0222644 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0219589 |
| S100A9 | S100 calcium binding protein A9 | -0.021602 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0212924 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0212863 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0210971 |
| RPS19 | ribosomal protein S19 | -0.020823 |
| CTSD | cathepsin D | -0.0206351 |
| RPS21 | ribosomal protein S21 | -0.0206077 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0205981 |
| SYT14 | synaptotagmin XIV | -0.0205622 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.020006 |
| MECOM | MDS1 and EVI1 complex locus | -0.0198395 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0198054 |
| VIM | vimentin | -0.0192343 |
| DAPK1 | death-associated protein kinase 1 | -0.0191432 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0191316 |
| FTL | ferritin, light polypeptide | -0.0187203 |
| MYL12B | myosin, light chain 12B, regulatory | -0.018707 |
| MT1X | metallothionein 1X | -0.0183862 |
| ECT2 | epithelial cell transforming 2 | -0.0182316 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0181114 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0176385 |
| KLK10 | kallikrein-related peptidase 10 | -0.0175871 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0175782 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0174426 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0172704 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0172081 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0172032 |
| MMP7 | matrix metallopeptidase 7 | -0.0169722 |
| RTN4 | reticulon 4 | -0.0169552 |
| TPM4 | tropomyosin 4 | -0.0169039 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0168876 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0168195 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.016798 |
| DEK | DEK proto-oncogene | -0.0167269 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0163469 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0163424 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0163334 |
| PGK1 | phosphoglycerate kinase 1 | -0.016255 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0160625 |
| EDN1 | endothelin 1 | -0.0160389 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0158683 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0157873 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0157363 |
| S100A10 | S100 calcium binding protein A10 | -0.0157324 |
| HMGB1 | high mobility group box 1 | -0.015675 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0156325 |
| S100A4 | S100 calcium binding protein A4 | -0.0155072 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0154493 |
| PERP | PERP, TP53 apoptosis effector | -0.0153684 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0153135 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.015281 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0151951 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0150665 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0149005 |
