| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.462832 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.268388 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.229032 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.190689 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.175724 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.162327 |
| FN1 | fibronectin 1 | 0.126255 |
| HLA-B | major histocompatibility complex, class I, B | 0.105378 |
| COL5A1 | collagen, type V, alpha 1 | 0.103456 |
| VEGFA | vascular endothelial growth factor A | 0.0942947 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0868536 |
| CALR | calreticulin | 0.0800514 |
| NDRG1 | N-myc downstream regulated 1 | 0.0799643 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0798926 |
| B2M | beta-2-microglobulin | 0.0769034 |
| NRXN3 | neurexin 3 | 0.0684735 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0675169 |
| VIM | vimentin | 0.0670807 |
| ENO1 | enolase 1, (alpha) | 0.066266 |
| CANX | calnexin | 0.0657569 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0632194 |
| CD44 | CD44 molecule (Indian blood group) | 0.061177 |
| LOXL2 | lysyl oxidase-like 2 | 0.0593578 |
| PLEC | plectin | 0.058905 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0581182 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0569462 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0553368 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.055196 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.05188 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0517935 |
| FLNA | filamin A, alpha | 0.0501223 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0495456 |
| CALU | calumenin | 0.0495334 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0483554 |
| ANXA2 | annexin A2 | 0.0469926 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0452761 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0443143 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0438102 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0436422 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0430542 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0429023 |
| CALD1 | caldesmon 1 | 0.0417767 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0408617 |
| COPA | coatomer protein complex, subunit alpha | 0.0404611 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0403065 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0392244 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0390768 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0386713 |
| HLA-C | major histocompatibility complex, class I, C | 0.0385202 |
| STC2 | stanniocalcin 2 | 0.0370796 |
| HIP1 | huntingtin interacting protein 1 | 0.0357643 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0356072 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.035497 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0349622 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.034798 |
| EXT1 | exostosin glycosyltransferase 1 | 0.034594 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0341691 |
| INTS6 | integrator complex subunit 6 | 0.0334244 |
| HDLBP | high density lipoprotein binding protein | 0.0331571 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0327619 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0327557 |
| GOLGB1 | golgin B1 | 0.0327312 |
| SDC4 | syndecan 4 | 0.0318195 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0317291 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0316747 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0314511 |
| HPCAL1 | hippocalcin-like 1 | 0.0312128 |
| AHNAK | AHNAK nucleoprotein | 0.0311205 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0306757 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0301023 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0300918 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0300406 |
| MLEC | malectin | 0.0300355 |
| GLG1 | golgi glycoprotein 1 | 0.029937 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297925 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0297708 |
| ARRDC3 | arrestin domain containing 3 | 0.0295224 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0294977 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0294976 |
| RIGI | RNA sensor RIG-I | 0.0294923 |
| HDAC9 | histone deacetylase 9 | 0.0293497 |
| CADM1 | cell adhesion molecule 1 | 0.0292567 |
| LDHA | lactate dehydrogenase A | 0.0292495 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0290746 |
| ANO6 | anoctamin 6 | 0.0288511 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0283398 |
| STC1 | stanniocalcin 1 | 0.0279188 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0278347 |
| SEC24D | SEC24 family member D | 0.0277561 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0277536 |
| PKM | pyruvate kinase, muscle | 0.027545 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0272733 |
| PRELID2 | PRELI domain containing 2 | 0.0272226 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0272224 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.026978 |
| CTSB | cathepsin B | 0.0267774 |
| VEGFC | vascular endothelial growth factor C | 0.0267769 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0267651 |
| ACTN1 | actinin, alpha 1 | 0.0266585 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0265942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.103091 |
| PTMA | prothymosin, alpha | -0.0451769 |
| MT1X | metallothionein 1X | -0.0358803 |
| PDE10A | phosphodiesterase 10A | -0.0318033 |
| RPS24 | ribosomal protein S24 | -0.0298729 |
| SMYD3 | SET and MYND domain containing 3 | -0.0282798 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0265717 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0251772 |
| EFNA5 | ephrin-A5 | -0.0247134 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0238104 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0228382 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0226771 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0219864 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0214 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0208825 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0206344 |
| RBM25 | RNA binding motif protein 25 | -0.0205811 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0199419 |
| ZNF292 | zinc finger protein 292 | -0.0196978 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0194362 |
| DST | dystonin | -0.019148 |
| RPL32 | ribosomal protein L32 | -0.0187883 |
| RPL26 | ribosomal protein L26 | -0.0187739 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0186481 |
| ANLN | anillin, actin binding protein | -0.0184108 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0180053 |
| MATR3 | matrin 3 | -0.0179918 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0179685 |
| RTN4 | reticulon 4 | -0.017932 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0178671 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0177654 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0176753 |
| GNAS | GNAS complex locus | -0.0175839 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0175454 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0175009 |
| PTN | pleiotrophin | -0.0174667 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0172882 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0171448 |
| RPS2 | ribosomal protein S2 | -0.0169154 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0168844 |
| FRMD6 | FERM domain containing 6 | -0.0167457 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0167156 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0166011 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0163801 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0161869 |
| DOCK7 | dedicator of cytokinesis 7 | -0.016162 |
| MSI2 | musashi RNA-binding protein 2 | -0.016112 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.016092 |
| JMJD1C | jumonji domain containing 1C | -0.0160694 |
| RPLP2 | ribosomal protein, large, P2 | -0.0159443 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0156332 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0155173 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0154078 |
| RPL11 | ribosomal protein L11 | -0.0151374 |
| RSF1 | remodeling and spacing factor 1 | -0.015035 |
| H3-3B | H3.3 histone B | -0.0149442 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0149273 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0148696 |
| RBM6 | RNA binding motif protein 6 | -0.0148566 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0145394 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0144752 |
| PFN1 | profilin 1 | -0.0144135 |
| EZR | ezrin | -0.0143197 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0143086 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0143032 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0142571 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0142015 |
| MPG | N-methylpurine-DNA glycosylase | -0.0141166 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0141129 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0140896 |
| RNF216 | ring finger protein 216 | -0.0140718 |
| MED13L | mediator complex subunit 13-like | -0.0139233 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0138757 |
| RORA | RAR-related orphan receptor A | -0.0138731 |
| PHKB | phosphorylase kinase, beta | -0.013697 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0136889 |
| AUTS2 | autism susceptibility candidate 2 | -0.0136326 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0135695 |
| RASA2 | RAS p21 protein activator 2 | -0.0135586 |
| FAM133B | family with sequence similarity 133, member B | -0.0135346 |
| TPD52 | tumor protein D52 | -0.0134916 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0134845 |
| EVI5 | ecotropic viral integration site 5 | -0.0134757 |
| DCP2 | decapping mRNA 2 | -0.0134755 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0134415 |
| QKI | QKI, KH domain containing, RNA binding | -0.0134324 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0134225 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0133344 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.013321 |
| RPLP1 | ribosomal protein, large, P1 | -0.0132801 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0132183 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0131468 |
| RBM27 | RNA binding motif protein 27 | -0.013144 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0131245 |
| NUBPL | nucleotide binding protein-like | -0.0130841 |
| LNPK | lunapark, ER junction formation factor | -0.0130216 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0130098 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0130022 |
| HMGB2 | high mobility group box 2 | -0.0130019 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0130012 |
