| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the TAK-733_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.148025 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.111933 |
| SMAD3 | SMAD family member 3 | 0.0809393 |
| LOC112694756 | uncharaterized LOC112694756 | 0.077715 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0770947 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0764825 |
| DST | dystonin | 0.0700794 |
| FLNA | filamin A, alpha | 0.0624192 |
| SVIL | supervillin | 0.0612797 |
| LDHA | lactate dehydrogenase A | 0.0582492 |
| SMYD3 | SET and MYND domain containing 3 | 0.0581194 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0576202 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.055923 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0545935 |
| ANXA2 | annexin A2 | 0.05136 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0513334 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.050299 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0496448 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0495958 |
| PLEC | plectin | 0.049266 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.048879 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0454472 |
| FMNL2 | formin-like 2 | 0.0442503 |
| CEP250 | centrosomal protein 250kDa | 0.043385 |
| ANO6 | anoctamin 6 | 0.0411424 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0410133 |
| ATXN1 | ataxin 1 | 0.0405701 |
| PKM | pyruvate kinase, muscle | 0.0392465 |
| FNDC3B | fibronectin type III domain containing 3B | 0.037649 |
| AHNAK | AHNAK nucleoprotein | 0.0363797 |
| SEPTIN9 | septin 9 | 0.0360942 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0360675 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.035885 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0358144 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0352361 |
| TXNRD1 | thioredoxin reductase 1 | 0.0349415 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0345712 |
| INTS6 | integrator complex subunit 6 | 0.033393 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0333366 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0328786 |
| RUNX1 | runt-related transcription factor 1 | 0.0328351 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0327937 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0327035 |
| HPCAL1 | hippocalcin-like 1 | 0.0326742 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0325212 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0322079 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0317831 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0314941 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0312888 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0312331 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0310996 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.030647 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0302847 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0301984 |
| PRRC2B | proline-rich coiled-coil 2B | 0.030028 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0299088 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296957 |
| ENO1 | enolase 1, (alpha) | 0.0294372 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.028648 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0285145 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0281499 |
| SIK2 | salt-inducible kinase 2 | 0.0278381 |
| SSH1 | slingshot protein phosphatase 1 | 0.0277186 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0269532 |
| NBEA | neurobeachin | 0.0268704 |
| PRKCA | protein kinase C, alpha | 0.0259651 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0257145 |
| PGK1 | phosphoglycerate kinase 1 | 0.0252417 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0244462 |
| NONO | non-POU domain containing, octamer-binding | 0.0244159 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.024132 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0239491 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0235296 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0234223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0232731 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0231943 |
| CAB39 | calcium binding protein 39 | 0.0231675 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0229532 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0224014 |
| TRRAP | transformation/transcription domain-associated protein | 0.0220657 |
| ARRDC3 | arrestin domain containing 3 | 0.0220568 |
| TMEM14B | transmembrane protein 14B | 0.0220554 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0219667 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0219399 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0218994 |
| SKIL | SKI-like proto-oncogene | 0.0218476 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0218131 |
| ASPH | aspartate beta-hydroxylase | 0.0217595 |
| TRIM44 | tripartite motif containing 44 | 0.0215101 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0213926 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0210476 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0210001 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0208624 |
| RAB31 | RAB31, member RAS oncogene family | 0.0208309 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0207361 |
| TMEM123 | transmembrane protein 123 | 0.0206451 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0202736 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0201844 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0195282 |
| GPHN | gephyrin | 0.0193294 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.126748 |
| TMSB10 | thymosin beta 10 | -0.102726 |
| VIM | vimentin | -0.064537 |
| PTMA | prothymosin, alpha | -0.063704 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0585346 |
| EGR1 | early growth response 1 | -0.0436869 |
| DNER | delta/notch-like EGF repeat containing | -0.0393852 |
| FTL | ferritin, light polypeptide | -0.0393799 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0381483 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0376006 |
| RPL35A | ribosomal protein L35a | -0.0361749 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0358262 |
| RPL19 | ribosomal protein L19 | -0.0347783 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0342303 |
| HMGA2 | high mobility group AT-hook 2 | -0.0331929 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0320241 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0318317 |
| IGF2 | insulin-like growth factor 2 | -0.0312747 |
| RPS29 | ribosomal protein S29 | -0.0300298 |
| CCDC88A | coiled-coil domain containing 88A | -0.0295577 |
| POTEF | POTE ankyrin domain family, member F | -0.0293878 |
| RPLP1 | ribosomal protein, large, P1 | -0.0282988 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0275747 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0266209 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0258256 |
| RPS13 | ribosomal protein S13 | -0.0255254 |
| RPL37A | ribosomal protein L37a | -0.0252809 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0242088 |
| MORF4L2 | mortality factor 4 like 2 | -0.0241059 |
| RPS6 | ribosomal protein S6 | -0.0236884 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0232597 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0231439 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0228782 |
| DIAPH3 | diaphanous-related formin 3 | -0.022604 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0225698 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0225481 |
| NKTR | natural killer cell triggering receptor | -0.0222332 |
| RPL31 | ribosomal protein L31 | -0.0221757 |
| S100A9 | S100 calcium binding protein A9 | -0.0220616 |
| RPS11 | ribosomal protein S11 | -0.0218413 |
| GOLGB1 | golgin B1 | -0.0215972 |
| CAPRIN2 | caprin family member 2 | -0.0215964 |
| GOLGA4 | golgin A4 | -0.0215201 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0212227 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0210553 |
| TPX2 | TPX2, microtubule-associated | -0.0209698 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0208533 |
| RPS25 | ribosomal protein S25 | -0.0206387 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0203527 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0201662 |
| RPL7A | ribosomal protein L7a | -0.0201479 |
| RPL12 | ribosomal protein L12 | -0.0201453 |
| RPS8 | ribosomal protein S8 | -0.0196876 |
| TAOK3 | TAO kinase 3 | -0.0192478 |
| HDLBP | high density lipoprotein binding protein | -0.0191335 |
| HM13 | histocompatibility (minor) 13 | -0.0188097 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0186725 |
| YBX3 | Y box binding protein 3 | -0.0186004 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0185909 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0184627 |
| COG5 | component of oligomeric golgi complex 5 | -0.018222 |
| RPL5 | ribosomal protein L5 | -0.0181284 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0180778 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0180622 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0180431 |
| ARL13B | ADP-ribosylation factor-like 13B | -0.0178811 |
| RPS27A | ribosomal protein S27a | -0.0178628 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0177381 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.0177314 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0175811 |
| HMGA1 | high mobility group AT-hook 1 | -0.0175143 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0174697 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0174661 |
| RPLP2 | ribosomal protein, large, P2 | -0.0172786 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0171927 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0171635 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0170325 |
| RPS14 | ribosomal protein S14 | -0.0168688 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0167519 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0167203 |
| MCL1 | myeloid cell leukemia 1 | -0.0166758 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0165924 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.016586 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0164937 |
| CCNH | cyclin H | -0.0164865 |
| SETD5 | SET domain containing 5 | -0.0164833 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0164808 |
| DEK | DEK proto-oncogene | -0.0164392 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0163698 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0163139 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.016211 |
| KIF20B | kinesin family member 20B | -0.0161522 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0161255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0160501 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0159847 |
| S100A6 | S100 calcium binding protein A6 | -0.0158645 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0157225 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0155813 |
| B2M | beta-2-microglobulin | -0.0150455 |
| SDCBP | syndecan binding protein (syntenin) | -0.014964 |
