| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC2 | stanniocalcin 2 | 0.190869 |
| FAT1 | FAT atypical cadherin 1 | 0.0877405 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0788623 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0730654 |
| VEGFA | vascular endothelial growth factor A | 0.0686396 |
| CD109 | CD109 molecule | 0.067355 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0666885 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0666825 |
| SMAD3 | SMAD family member 3 | 0.0652677 |
| SFTPA2 | surfactant protein A2 | 0.0610891 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.060996 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0586615 |
| EXT1 | exostosin glycosyltransferase 1 | 0.057817 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0571515 |
| RUNX1 | runt-related transcription factor 1 | 0.0560779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0546365 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0542891 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0512557 |
| ENAH | enabled homolog (Drosophila) | 0.0502666 |
| MYOF | myoferlin | 0.0494528 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0472976 |
| SEPTIN9 | septin 9 | 0.0471601 |
| IL6ST | interleukin 6 signal transducer | 0.045962 |
| PLEC | plectin | 0.0450318 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0437069 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0422063 |
| FLNA | filamin A, alpha | 0.042135 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0411443 |
| APP | amyloid beta (A4) precursor protein | 0.040168 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0398892 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0396602 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0390324 |
| RACK1 | receptor for activated C kinase 1 | 0.0377404 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0369521 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0362739 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0356225 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0349978 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0349521 |
| CFB | complement factor B | 0.0341838 |
| DST | dystonin | 0.0337751 |
| TXNRD1 | thioredoxin reductase 1 | 0.0333901 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0333615 |
| ARRDC3 | arrestin domain containing 3 | 0.0324566 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.032317 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0316816 |
| NXN | nucleoredoxin | 0.0313899 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0308987 |
| SSH1 | slingshot protein phosphatase 1 | 0.030878 |
| EREG | epiregulin | 0.0303652 |
| TXNIP | thioredoxin interacting protein | 0.0302928 |
| RBPMS | RNA binding protein with multiple splicing | 0.0298485 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0294043 |
| DSTN | destrin (actin depolymerizing factor) | 0.0289383 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0287672 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0285527 |
| RNF220 | ring finger protein 220 | 0.0284506 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0283353 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0281933 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0277955 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0272815 |
| LMNA | lamin A/C | 0.0271165 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0269807 |
| CAB39 | calcium binding protein 39 | 0.0269279 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0266716 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0266552 |
| GLUL | glutamate-ammonia ligase | 0.0254596 |
| SMYD3 | SET and MYND domain containing 3 | 0.025396 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0253274 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0252622 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0252416 |
| B2M | beta-2-microglobulin | 0.0251008 |
| SH3BP4 | SH3-domain binding protein 4 | 0.0250653 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0247194 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0240392 |
| GAK | cyclin G associated kinase | 0.0240141 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0239634 |
| RNF213 | ring finger protein 213 | 0.023924 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238876 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0237817 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0236857 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.023437 |
| PCDH7 | protocadherin 7 | 0.0231625 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.02315 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0231467 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 | 0.0228026 |
| ACTG1 | actin gamma 1 | 0.0225219 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0222939 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0221911 |
| PALLD | palladin, cytoskeletal associated protein | 0.0219974 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0216702 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0216373 |
| MB21D2 | Mab-21 domain containing 2 | 0.0215927 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.021513 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.021389 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0212607 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.0211169 |
| CORO1C | coronin, actin binding protein, 1C | 0.0207839 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.020773 |
| ATF3 | activating transcription factor 3 | 0.0207485 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0207445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.22399 |
| HMGA2 | high mobility group AT-hook 2 | -0.16562 |
| FN1 | fibronectin 1 | -0.123997 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.10849 |
| PTMA | prothymosin, alpha | -0.0976197 |
| TMSB10 | thymosin beta 10 | -0.0888728 |
| ITGA1 | integrin, alpha 1 | -0.0836412 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0817795 |
| EFNA5 | ephrin-A5 | -0.063012 |
| MT2A | metallothionein 2A | -0.0573853 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0573462 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0558385 |
| ASPH | aspartate beta-hydroxylase | -0.0538718 |
| GLIS3 | GLIS family zinc finger 3 | -0.050378 |
| S100A6 | S100 calcium binding protein A6 | -0.045167 |
| RAI14 | retinoic acid induced 14 | -0.0442624 |
| TMEM165 | transmembrane protein 165 | -0.0441539 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0433063 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.037338 |
| VIM | vimentin | -0.037232 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.036517 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363391 |
| ETV1 | ets variant 1 | -0.0362246 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0360624 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0330296 |
| VMP1 | vacuole membrane protein 1 | -0.0326342 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324463 |
| RTN4 | reticulon 4 | -0.0321874 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0306728 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0300381 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0293364 |
| HMGA1 | high mobility group AT-hook 1 | -0.0292977 |
| PLIN2 | perilipin 2 | -0.0291084 |
| SPAG9 | sperm associated antigen 9 | -0.028905 |
| VCL | vinculin | -0.0288512 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0282854 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0269521 |
| TMSB4X | thymosin beta 4, X-linked | -0.0266957 |
| FTL | ferritin, light polypeptide | -0.0265118 |
| GNAS | GNAS complex locus | -0.0259468 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0258298 |
| RPS6 | ribosomal protein S6 | -0.0257644 |
| IL6 | interleukin 6 | -0.0257317 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0251038 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0249572 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0248735 |
| SMOX | spermine oxidase | -0.024677 |
| RPL35A | ribosomal protein L35a | -0.024368 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0238289 |
| RPS24 | ribosomal protein S24 | -0.023477 |
| IER3 | immediate early response 3 | -0.0230722 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0229078 |
| TGFA | transforming growth factor, alpha | -0.0227996 |
| DUSP5 | dual specificity phosphatase 5 | -0.0222962 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0218493 |
| FBXO11 | F-box protein 11 | -0.0215136 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0214732 |
| PARD3 | par-3 family cell polarity regulator | -0.0211623 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0211068 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0210592 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.020944 |
| EGR1 | early growth response 1 | -0.0204543 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0204226 |
| CTSD | cathepsin D | -0.0203561 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0202909 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0202545 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0202242 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0201664 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0201489 |
| RPLP1 | ribosomal protein, large, P1 | -0.0201054 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0199823 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0198246 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0197829 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0195708 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0195654 |
| SYT1 | synaptotagmin I | -0.0195242 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0193811 |
| LOX | lysyl oxidase | -0.0192154 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0192114 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0191192 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0189158 |
| VEGFC | vascular endothelial growth factor C | -0.0185783 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0183325 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0182729 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.018131 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0179564 |
| PCNX4 | pecanex 4 | -0.0178113 |
| RPLP2 | ribosomal protein, large, P2 | -0.017125 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0171198 |
| TENM4 | teneurin transmembrane protein 4 | -0.0168875 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0168791 |
| OSMR | oncostatin M receptor | -0.0167258 |
| AHNAK | AHNAK nucleoprotein | -0.016654 |
| KLF12 | Kruppel-like factor 12 | -0.0164171 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0164148 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0164131 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0163066 |
| UBXN4 | UBX domain protein 4 | -0.0162609 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0161848 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0161637 |
