| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.19478 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.189994 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.163106 |
| PLEC | plectin | 0.131567 |
| TNS3 | tensin 3 | 0.123952 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.121404 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.115548 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.112698 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.110474 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.110292 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0984595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0911621 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0890189 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0875539 |
| DSPP | dentin sialophosphoprotein | 0.077337 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0750171 |
| NONO | non-POU domain containing, octamer-binding | 0.0702585 |
| AXIN2 | axin 2 | 0.0668373 |
| LMO7 | LIM domain 7 | 0.0639028 |
| FAT1 | FAT atypical cadherin 1 | 0.0601512 |
| WWOX | WW domain containing oxidoreductase | 0.0595125 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0562332 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0552458 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0548735 |
| FLNA | filamin A, alpha | 0.0534111 |
| RPS12 | ribosomal protein S12 | 0.051601 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.0512924 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0499744 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0496147 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0492384 |
| RACK1 | receptor for activated C kinase 1 | 0.0491333 |
| LDHA | lactate dehydrogenase A | 0.0472701 |
| SMAD3 | SMAD family member 3 | 0.0467675 |
| RPL3 | ribosomal protein L3 | 0.046524 |
| SYT1 | synaptotagmin I | 0.0463665 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0461726 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0458965 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.044962 |
| ZNRF3 | zinc and ring finger 3 | 0.0449596 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0447437 |
| AOPEP | aminopeptidase O (putative) | 0.0442237 |
| ANXA2 | annexin A2 | 0.0435059 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0426088 |
| YBX1 | Y box binding protein 1 | 0.0424903 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0419483 |
| SPATA13 | spermatogenesis associated 13 | 0.0418776 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0418117 |
| SET | SET nuclear proto-oncogene | 0.0414531 |
| HDAC4 | histone deacetylase 4 | 0.041293 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.040863 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0407395 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0405632 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0399794 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0399418 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0389963 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0380258 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.037273 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0368065 |
| SEPTIN9 | septin 9 | 0.0366434 |
| KRT18 | keratin 18, type I | 0.0365505 |
| ACTN1 | actinin, alpha 1 | 0.0363629 |
| FUS | FUS RNA binding protein | 0.0363152 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0358533 |
| RPS8 | ribosomal protein S8 | 0.0357799 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0352876 |
| YAP1 | Yes-associated protein 1 | 0.0350395 |
| DST | dystonin | 0.0349694 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0347714 |
| RUNX1 | runt-related transcription factor 1 | 0.0346303 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0342362 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0341334 |
| ENO1 | enolase 1, (alpha) | 0.0335534 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0333632 |
| RPS3 | ribosomal protein S3 | 0.0330719 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0330191 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0330119 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0328787 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0326516 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.0325967 |
| PGK1 | phosphoglycerate kinase 1 | 0.032226 |
| SERINC5 | serine incorporator 5 | 0.0317139 |
| BRD2 | bromodomain containing 2 | 0.0316352 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.031051 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0309109 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0306738 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0306446 |
| CMIP | c-Maf inducing protein | 0.030611 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0303898 |
| TMEM123 | transmembrane protein 123 | 0.0303668 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0302773 |
| STK38L | serine/threonine kinase 38 like | 0.0302144 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0301578 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0300946 |
| TNNC1 | troponin C type 1 (slow) | 0.0300726 |
| CANX | calnexin | 0.0296434 |
| BPTF | bromodomain PHD finger transcription factor | 0.0295528 |
| RPLP0 | ribosomal protein, large, P0 | 0.0289413 |
| SYK | spleen tyrosine kinase | 0.0287047 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0283202 |
| ACTN4 | actinin, alpha 4 | 0.028262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0992718 |
| CCND1 | cyclin D1 | -0.0813191 |
| TMSB10 | thymosin beta 10 | -0.0701747 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0641835 |
| PTMA | prothymosin, alpha | -0.056545 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0482949 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0477074 |
| RPS24 | ribosomal protein S24 | -0.0427316 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0410717 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0339707 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0335384 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0334645 |
| AHNAK | AHNAK nucleoprotein | -0.0325593 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0317168 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0310245 |
| DUSP6 | dual specificity phosphatase 6 | -0.0263496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0262375 |
| VCL | vinculin | -0.0260673 |
| ANLN | anillin, actin binding protein | -0.025853 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0244653 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0243843 |
| DIAPH3 | diaphanous-related formin 3 | -0.0243031 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0242499 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0239364 |
| RBM25 | RNA binding motif protein 25 | -0.0237933 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0234121 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0228721 |
| GNAS | GNAS complex locus | -0.0216474 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0216259 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.020736 |
| RTN3 | reticulon 3 | -0.0196097 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0194926 |
| DEK | DEK proto-oncogene | -0.0190831 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0181567 |
| TPM4 | tropomyosin 4 | -0.0180008 |
| NAV2 | neuron navigator 2 | -0.017806 |
| ITGB4 | integrin, beta 4 | -0.0177894 |
| TMEM41B | transmembrane protein 41B | -0.0176613 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0172697 |
| RPL35A | ribosomal protein L35a | -0.017225 |
| RASA2 | RAS p21 protein activator 2 | -0.0169914 |
| ECT2 | epithelial cell transforming 2 | -0.0167052 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0166668 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0165537 |
| HMGB1 | high mobility group box 1 | -0.0165 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0164171 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0160841 |
| ETNK1 | ethanolamine kinase 1 | -0.0160417 |
| RPL27A | ribosomal protein L27a | -0.015578 |
| SBF2 | SET binding factor 2 | -0.0155028 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.015475 |
| CEP95 | centrosomal protein 95kDa | -0.015448 |
| HMGA1 | high mobility group AT-hook 1 | -0.0151384 |
| OXR1 | oxidation resistance 1 | -0.0149877 |
| TUT4 | terminal uridylyl transferase 4 | -0.0147867 |
| ITGA6 | integrin, alpha 6 | -0.0146107 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0144603 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0143815 |
| USP34 | ubiquitin specific peptidase 34 | -0.0141272 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0140275 |
| POU2F1 | POU class 2 homeobox 1 | -0.0139691 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0139615 |
| JMJD1C | jumonji domain containing 1C | -0.0138921 |
| ABLIM1 | actin binding LIM protein 1 | -0.013816 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0137519 |
| S100A6 | S100 calcium binding protein A6 | -0.013587 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.013503 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0133584 |
| CDH13 | cadherin 13 | -0.0133406 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.013186 |
| ERBIN | erbb2 interacting protein | -0.0130406 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0129657 |
| PROX1 | prospero homeobox 1 | -0.0129403 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.012877 |
| CCDC82 | coiled-coil domain containing 82 | -0.0127997 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0127925 |
| PERP | PERP, TP53 apoptosis effector | -0.0127625 |
| ITGB5 | integrin, beta 5 | -0.0127192 |
| FBXO34 | F-box protein 34 | -0.0126753 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0125385 |
| TES | testin LIM domain protein | -0.0123766 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0122822 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0122743 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0122432 |
| NBEAL1 | neurobeachin-like 1 | -0.012073 |
| UTRN | utrophin | -0.0120441 |
| ARF4 | ADP-ribosylation factor 4 | -0.0120075 |
| VMP1 | vacuole membrane protein 1 | -0.0119938 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0119222 |
| ETV5 | ets variant 5 | -0.0118592 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0118345 |
| RPL34 | ribosomal protein L34 | -0.0118105 |
| BCL2L1 | BCL2-like 1 | -0.0117942 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0117911 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0117729 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0116988 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.011691 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0115857 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0114967 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0114768 |
