| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-733 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-733_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.474319 |
| COL6A3 | collagen, type VI, alpha 3 | 0.382732 |
| INHBA | inhibin, beta A | 0.174538 |
| HMGA2 | high mobility group AT-hook 2 | 0.153894 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.14268 |
| MYO10 | myosin X | 0.131666 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.125814 |
| NAV1 | neuron navigator 1 | 0.105541 |
| COL6A2 | collagen, type VI, alpha 2 | 0.10254 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0957869 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0938064 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0922934 |
| CD44 | CD44 molecule (Indian blood group) | 0.0881708 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0877768 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0824354 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.079682 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0780365 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0756625 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0748743 |
| MMP1 | matrix metallopeptidase 1 | 0.0748578 |
| HLA-B | major histocompatibility complex, class I, B | 0.0730769 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0717897 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0708046 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0676687 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0670169 |
| FBN1 | fibrillin 1 | 0.0651642 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0624385 |
| STC1 | stanniocalcin 1 | 0.0624369 |
| ASPH | aspartate beta-hydroxylase | 0.0624063 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0604533 |
| VEGFA | vascular endothelial growth factor A | 0.0583472 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0579118 |
| EGFR | epidermal growth factor receptor | 0.05694 |
| GLIS3 | GLIS family zinc finger 3 | 0.0567377 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0551857 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0483909 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0482762 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0476089 |
| COL1A1 | collagen, type I, alpha 1 | 0.047497 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0460147 |
| B2M | beta-2-microglobulin | 0.0449811 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0448645 |
| PLEC | plectin | 0.044502 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0435635 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0427263 |
| CDH13 | cadherin 13 | 0.0424193 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0422387 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0407752 |
| DST | dystonin | 0.040709 |
| CALD1 | caldesmon 1 | 0.0384192 |
| VCL | vinculin | 0.0383284 |
| COL1A2 | collagen, type I, alpha 2 | 0.0383115 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0380954 |
| FRMD4A | FERM domain containing 4A | 0.0375698 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0372671 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0370934 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0357389 |
| FLNA | filamin A, alpha | 0.0356629 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0354538 |
| SEPTIN9 | septin 9 | 0.0344445 |
| INTS6 | integrator complex subunit 6 | 0.0342802 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0342261 |
| EMP1 | epithelial membrane protein 1 | 0.0341639 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0336207 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.033587 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0327169 |
| COL5A1 | collagen, type V, alpha 1 | 0.0326801 |
| AHNAK | AHNAK nucleoprotein | 0.0325697 |
| FAT1 | FAT atypical cadherin 1 | 0.0325259 |
| ACTG1 | actin gamma 1 | 0.0324459 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0316081 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0305822 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0305471 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0301407 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0299059 |
| OXR1 | oxidation resistance 1 | 0.0298246 |
| LOXL2 | lysyl oxidase-like 2 | 0.0297772 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.029704 |
| KIAA1549L | KIAA1549-like | 0.0296642 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0296094 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0293778 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0292197 |
| HDAC9 | histone deacetylase 9 | 0.0291202 |
| PRELID2 | PRELI domain containing 2 | 0.0290625 |
| CLMP | CXADR-like membrane protein | 0.0290575 |
| EGR1 | early growth response 1 | 0.0287616 |
| PDLIM5 | PDZ and LIM domain 5 | 0.028673 |
| RAI14 | retinoic acid induced 14 | 0.0284605 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0284139 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.027997 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0278925 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0278031 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.027574 |
| RUNX1 | runt-related transcription factor 1 | 0.0273528 |
| SFTPA2 | surfactant protein A2 | 0.0272937 |
| IGF2 | insulin-like growth factor 2 | 0.0270722 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270447 |
| APP | amyloid beta (A4) precursor protein | 0.0267984 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0267395 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0265921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.0744848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0628619 |
| FAM13A | family with sequence similarity 13, member A | -0.0553132 |
| GOLGA4 | golgin A4 | -0.0438305 |
| FTL | ferritin, light polypeptide | -0.0425235 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0422856 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0400673 |
| SPAG9 | sperm associated antigen 9 | -0.0345884 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0315199 |
| ZNF292 | zinc finger protein 292 | -0.0295764 |
| PTMA | prothymosin, alpha | -0.0294675 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0265344 |
| USP3 | ubiquitin specific peptidase 3 | -0.0262718 |
| ADM | adrenomedullin | -0.0261476 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0260307 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0258262 |
| MT2A | metallothionein 2A | -0.0245781 |
| YBX3 | Y box binding protein 3 | -0.0236712 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0214348 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0211123 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0208315 |
| RTN4 | reticulon 4 | -0.0205623 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0203742 |
| HMGB2 | high mobility group box 2 | -0.0199549 |
| NUP58 | nucleoporin 58 | -0.0198369 |
| RNF145 | ring finger protein 145 | -0.0195537 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0195395 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0191366 |
| CENPF | centromere protein F, 350/400kDa | -0.0190377 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0183981 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0182888 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0179488 |
| CLINT1 | clathrin interactor 1 | -0.0176155 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0169107 |
| OGA | O-GlcNAcase | -0.0168485 |
| SRP54 | signal recognition particle 54kDa | -0.0168426 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0166943 |
| SETD5 | SET domain containing 5 | -0.0164884 |
| SUCO | SUN domain containing ossification factor | -0.016372 |
| SRGN | serglycin | -0.0161852 |
| NOP58 | NOP58 ribonucleoprotein | -0.0157796 |
| RPS6 | ribosomal protein S6 | -0.0154833 |
| MORF4L2 | mortality factor 4 like 2 | -0.0154523 |
| S100A6 | S100 calcium binding protein A6 | -0.0153181 |
| RPLP1 | ribosomal protein, large, P1 | -0.0151917 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0148925 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0148288 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0147556 |
| HELZ | helicase with zinc finger | -0.0147436 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0147109 |
| RPS2 | ribosomal protein S2 | -0.0146947 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0144505 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0143153 |
| RLF | rearranged L-myc fusion | -0.0142396 |
| CCNL1 | cyclin L1 | -0.014228 |
| CDC27 | cell division cycle 27 | -0.014194 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.014144 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.014019 |
| WDR45B | WD repeat domain 45B | -0.0139179 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0139083 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0138778 |
| ANLN | anillin, actin binding protein | -0.0137567 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0137353 |
| FOXO3 | forkhead box O3 | -0.0136806 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0136663 |
| XPO1 | exportin 1 | -0.0136463 |
| TFG | TRK-fused gene | -0.0135766 |
| TMSB10 | thymosin beta 10 | -0.013443 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0134051 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0132983 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0131936 |
| PHIP | pleckstrin homology domain interacting protein | -0.0131 |
| RBM39 | RNA binding motif protein 39 | -0.0130397 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0128798 |
| NDRG1 | N-myc downstream regulated 1 | -0.0126189 |
| MSI2 | musashi RNA-binding protein 2 | -0.0125714 |
| PCBP2 | poly(rC) binding protein 2 | -0.0125016 |
| FAM162A | family with sequence similarity 162, member A | -0.0123782 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0123364 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0123186 |
| RARS1 | arginyl-tRNA synthetase 1 | -0.012305 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0122014 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0121397 |
| HMGA1 | high mobility group AT-hook 1 | -0.0119931 |
| ZNF654 | zinc finger protein 654 | -0.0119345 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0118202 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0115908 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0115079 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0115044 |
| SYAP1 | synapse associated protein 1 | -0.011467 |
| WDR43 | WD repeat domain 43 | -0.0110665 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0110505 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0110046 |
| SEC24A | SEC24 family member A | -0.011002 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0108696 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.010711 |
| ECD | ecdysoneless homolog (Drosophila) | -0.0106894 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0106854 |
| COG5 | component of oligomeric golgi complex 5 | -0.0106815 |
| TPX2 | TPX2, microtubule-associated | -0.0106609 |
