| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.102211 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.100053 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0992681 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0874738 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.071951 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0715996 |
| JMJD1C | jumonji domain containing 1C | 0.0702071 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0696622 |
| RPS6 | ribosomal protein S6 | 0.064541 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0627624 |
| VIM | vimentin | 0.06202 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.056695 |
| MED13L | mediator complex subunit 13-like | 0.0556356 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0547194 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0542897 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0538189 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0537781 |
| WDR43 | WD repeat domain 43 | 0.0535611 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0534643 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0525193 |
| MYOF | myoferlin | 0.0503046 |
| CTBP2 | C-terminal binding protein 2 | 0.0498736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0496283 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0491964 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0483876 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0479273 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0475903 |
| RPL37A | ribosomal protein L37a | 0.0472735 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0468276 |
| RPL31 | ribosomal protein L31 | 0.0447077 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0442266 |
| RLF | rearranged L-myc fusion | 0.0439423 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0435286 |
| BPTF | bromodomain PHD finger transcription factor | 0.043037 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0418439 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0408083 |
| RPS3 | ribosomal protein S3 | 0.0404297 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.040298 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0401522 |
| RPS8 | ribosomal protein S8 | 0.039716 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.039618 |
| ANKRD12 | ankyrin repeat domain 12 | 0.039474 |
| RPS12 | ribosomal protein S12 | 0.0391017 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0389537 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0388906 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0385511 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0384576 |
| RPS23 | ribosomal protein S23 | 0.0380528 |
| PRRC2C | proline-rich coiled-coil 2C | 0.037831 |
| BRD4 | bromodomain containing 4 | 0.0374055 |
| RACK1 | receptor for activated C kinase 1 | 0.0372894 |
| IER3 | immediate early response 3 | 0.03677 |
| QKI | QKI, KH domain containing, RNA binding | 0.0365134 |
| MB21D2 | Mab-21 domain containing 2 | 0.0364051 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0362632 |
| CDK6 | cyclin-dependent kinase 6 | 0.0360699 |
| YBX1 | Y box binding protein 1 | 0.0358077 |
| HMGA2 | high mobility group AT-hook 2 | 0.0356943 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0356819 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0351841 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0345028 |
| CDK13 | cyclin-dependent kinase 13 | 0.0344734 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0343272 |
| EGFR | epidermal growth factor receptor | 0.0340801 |
| SETD2 | SET domain containing 2 | 0.0338643 |
| FRMD6 | FERM domain containing 6 | 0.0338428 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0335918 |
| CCNL1 | cyclin L1 | 0.0332256 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0331158 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0329597 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0327294 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0326896 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0326261 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0325982 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0322883 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0321305 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0318162 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0318139 |
| SON | SON DNA binding protein | 0.0317213 |
| EZR | ezrin | 0.0315719 |
| RBM33 | RNA binding motif protein 33 | 0.0315522 |
| RBM39 | RNA binding motif protein 39 | 0.0315172 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315091 |
| HMGA1 | high mobility group AT-hook 1 | 0.0312093 |
| CRY1 | cryptochrome circadian clock 1 | 0.0311668 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0307952 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0306742 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0302531 |
| RBM25 | RNA binding motif protein 25 | 0.0302396 |
| ANO6 | anoctamin 6 | 0.0301836 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0301695 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0299687 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0298237 |
| ERBIN | erbb2 interacting protein | 0.0296807 |
| NFYA | nuclear transcription factor Y, alpha | 0.029649 |
| CCNY | cyclin Y | 0.0295367 |
| RPS25 | ribosomal protein S25 | 0.0291717 |
| NOP58 | NOP58 ribonucleoprotein | 0.029043 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0288514 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0286074 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.164383 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10773 |
| MEOX2 | mesenchyme homeobox 2 | -0.0507283 |
| RPLP1 | ribosomal protein, large, P1 | -0.0501048 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0475351 |
| COL1A2 | collagen, type I, alpha 2 | -0.0417009 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0390977 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0377589 |
| GSE1 | Gse1 coiled-coil protein | -0.0356117 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0352497 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0342219 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0339177 |
| MT2A | metallothionein 2A | -0.033755 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0324339 |
| TUBB | tubulin, beta class I | -0.0319465 |
| CENPF | centromere protein F, 350/400kDa | -0.0294908 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0291705 |
| PRELID2 | PRELI domain containing 2 | -0.0287374 |
| NFIA | nuclear factor I/A | -0.0269706 |
| CCNI | cyclin I | -0.0263631 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0256879 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0253349 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0252344 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0248577 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0248232 |
| TUT4 | terminal uridylyl transferase 4 | -0.0243747 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0242893 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0238923 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0216443 |
| GNAS | GNAS complex locus | -0.0211951 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0211575 |
| ITGAV | integrin, alpha V | -0.0211572 |
| ITM2B | integral membrane protein 2B | -0.0208385 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0205539 |
| LMO4 | LIM domain only 4 | -0.0201614 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.0201525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0200912 |
| HMGB1 | high mobility group box 1 | -0.0199399 |
| WASF2 | WAS protein family, member 2 | -0.0199117 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0197238 |
| OGA | O-GlcNAcase | -0.0196523 |
| MORF4L2 | mortality factor 4 like 2 | -0.0195173 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.019395 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0192428 |
| FANCI | Fanconi anemia, complementation group I | -0.0191242 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0190117 |
| MT1X | metallothionein 1X | -0.018558 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.0185532 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0184869 |
| CENPP | centromere protein P | -0.0183389 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0181811 |
| RPLP0 | ribosomal protein, large, P0 | -0.0180283 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0179836 |
| CCDC14 | coiled-coil domain containing 14 | -0.0179741 |
| KNL1 | kinetochore scaffold 1 | -0.017878 |
| R3HDM1 | R3H domain containing 1 | -0.0178354 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0175715 |
| TMPO | thymopoietin | -0.0175259 |
| CDK19 | cyclin-dependent kinase 19 | -0.0174668 |
| RAD21 | RAD21 homolog (S. pombe) | -0.017299 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0169795 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0169712 |
| CANX | calnexin | -0.0168051 |
| FADS2 | fatty acid desaturase 2 | -0.0166443 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0164646 |
| PCM1 | pericentriolar material 1 | -0.0164138 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0164098 |
| CBX3 | chromobox homolog 3 | -0.0162759 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0162265 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.016134 |
| TTK | TTK protein kinase | -0.0160662 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0160074 |
| SERINC3 | serine incorporator 3 | -0.0159922 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.0159136 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0156616 |
| PEG10 | paternally expressed 10 | -0.0154677 |
| CD70 | CD70 molecule | -0.0154662 |
| TUBA1B | tubulin, alpha 1b | -0.0154391 |
| NHLRC2 | NHL repeat containing 2 | -0.0149633 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.0149414 |
| ETV1 | ets variant 1 | -0.0148255 |
| MTX2 | metaxin 2 | -0.0147029 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0147017 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0146774 |
| DEPDC1 | DEP domain containing 1 | -0.0146563 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0146262 |
| PHIP | pleckstrin homology domain interacting protein | -0.0146239 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0145578 |
| NUCB2 | nucleobindin 2 | -0.0145033 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0144693 |
| CEP57L1 | centrosomal protein 57kDa-like 1 | -0.0144561 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.014371 |
| ZNF680 | zinc finger protein 680 | -0.0143249 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0143016 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.01428 |
| USP3 | ubiquitin specific peptidase 3 | -0.0142054 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0142054 |
| CDCA2 | cell division cycle associated 2 | -0.01418 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0140638 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0140635 |
