| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.140874 |
| ZNF608 | zinc finger protein 608 | 0.0941104 |
| RCC1 | regulator of chromosome condensation 1 | 0.0924658 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0923892 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0909618 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0886121 |
| COL5A2 | collagen, type V, alpha 2 | 0.0883005 |
| JMJD1C | jumonji domain containing 1C | 0.0761703 |
| TENM3 | teneurin transmembrane protein 3 | 0.0759242 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0671829 |
| NEBL | nebulette | 0.0666412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0652384 |
| RPS6 | ribosomal protein S6 | 0.0606547 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0601396 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0485023 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.045666 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0453174 |
| RPS3 | ribosomal protein S3 | 0.043358 |
| PHF3 | PHD finger protein 3 | 0.0422789 |
| ZNF638 | zinc finger protein 638 | 0.042262 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0415207 |
| RPL37A | ribosomal protein L37a | 0.0412741 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0411089 |
| JUN | jun proto-oncogene | 0.0410441 |
| MLIP | muscular LMNA-interacting protein | 0.0409757 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.040588 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0403126 |
| UBAP2 | ubiquitin associated protein 2 | 0.0402753 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0399944 |
| INTS6 | integrator complex subunit 6 | 0.0390467 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0388885 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0380154 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0378396 |
| CCDC88A | coiled-coil domain containing 88A | 0.0377263 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0375381 |
| USP34 | ubiquitin specific peptidase 34 | 0.0371598 |
| PNN | pinin, desmosome associated protein | 0.0366893 |
| RPS12 | ribosomal protein S12 | 0.0365938 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0363921 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0363575 |
| VMP1 | vacuole membrane protein 1 | 0.0362909 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0362843 |
| NBEAL1 | neurobeachin-like 1 | 0.0361208 |
| VCL | vinculin | 0.0360272 |
| BNC2 | basonuclin 2 | 0.0356734 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0353772 |
| BRD2 | bromodomain containing 2 | 0.0353514 |
| DST | dystonin | 0.0349553 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0347286 |
| MSH4 | mutS homolog 4 | 0.0345637 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0334954 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0331052 |
| HOMER1 | homer scaffolding protein 1 | 0.0330715 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.032985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0328663 |
| SON | SON DNA binding protein | 0.0322507 |
| BPTF | bromodomain PHD finger transcription factor | 0.0318011 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0317516 |
| SCFD1 | sec1 family domain containing 1 | 0.0317254 |
| ATP11A | ATPase, class VI, type 11A | 0.0316882 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.031551 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0312369 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0311784 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0309309 |
| FMNL2 | formin-like 2 | 0.0309215 |
| SIK3 | SIK family kinase 3 | 0.0309015 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.030756 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0306046 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0303947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298932 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0295219 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0294507 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0290359 |
| WLS | wntless Wnt ligand secretion mediator | 0.0286688 |
| SNX14 | sorting nexin 14 | 0.0284815 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0281868 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0279937 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0277847 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0275684 |
| AEBP2 | AE binding protein 2 | 0.0269489 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0269086 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0269028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.026878 |
| RPS18 | ribosomal protein S18 | 0.026872 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0268498 |
| YLPM1 | YLP motif containing 1 | 0.0267742 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0266712 |
| PCM1 | pericentriolar material 1 | 0.0264563 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0264167 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0263342 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0262807 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0262557 |
| SIK2 | salt-inducible kinase 2 | 0.0261538 |
| GPATCH2L | G patch domain containing 2-like | 0.0261096 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0260537 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258833 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0258536 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.025816 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0257798 |
| RCOR1 | REST corepressor 1 | 0.0254255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.129088 |
| PTMA | prothymosin, alpha | -0.123095 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.103541 |
| TMSB10 | thymosin beta 10 | -0.0885014 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0842361 |
| ACTG1 | actin gamma 1 | -0.0839812 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0798477 |
| RPS21 | ribosomal protein S21 | -0.0773041 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0727314 |
| RPLP1 | ribosomal protein, large, P1 | -0.072079 |
| RPL34 | ribosomal protein L34 | -0.0690514 |
| HMGB1 | high mobility group box 1 | -0.0683583 |
| RPS24 | ribosomal protein S24 | -0.0660015 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0649526 |
| PGK1 | phosphoglycerate kinase 1 | -0.0615661 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0595756 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0592841 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0558464 |
| LDHA | lactate dehydrogenase A | -0.0541901 |
| TUBB | tubulin, beta class I | -0.0534645 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0483611 |
| PFN1 | profilin 1 | -0.047964 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.046469 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0453834 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0452459 |
| RPL12 | ribosomal protein L12 | -0.044875 |
| NPAS3 | neuronal PAS domain protein 3 | -0.044331 |
| EGR1 | early growth response 1 | -0.0439611 |
| TXNRD1 | thioredoxin reductase 1 | -0.0438868 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0427811 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0427457 |
| RAD51B | RAD51 paralog B | -0.041654 |
| RPL35A | ribosomal protein L35a | -0.0413988 |
| H1-0 | H1.0 linker histone | -0.0411786 |
| RPL27A | ribosomal protein L27a | -0.0397953 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0391808 |
| HMGA1 | high mobility group AT-hook 1 | -0.0391529 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0388184 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0382946 |
| SHROOM3 | shroom family member 3 | -0.0382854 |
| TUBA1B | tubulin, alpha 1b | -0.0381677 |
| FAM162A | family with sequence similarity 162, member A | -0.0381314 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0369576 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0368874 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358659 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0347206 |
| RIGI | RNA sensor RIG-I | -0.0326866 |
| RPL23 | ribosomal protein L23 | -0.0325887 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0325333 |
| CAVIN1 | caveolae associated protein 1 | -0.0320874 |
| FBL | fibrillarin | -0.0308048 |
| RAN | RAN, member RAS oncogene family | -0.0306515 |
| RPL4 | ribosomal protein L4 | -0.0305873 |
| RPS28 | ribosomal protein S28 | -0.0305475 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0304756 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0301805 |
| CENPF | centromere protein F, 350/400kDa | -0.0301573 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.0297311 |
| S100A9 | S100 calcium binding protein A9 | -0.0296455 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0295952 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0293715 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0291246 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.029053 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.029008 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0288613 |
| RPLP0 | ribosomal protein, large, P0 | -0.0282967 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0282227 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0281188 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0280032 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0278917 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0278827 |
| MAGEA4 | melanoma antigen family A4 | -0.0278001 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0275655 |
| GNAS | GNAS complex locus | -0.0274138 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272905 |
| CBX3 | chromobox homolog 3 | -0.0272776 |
| RPS14 | ribosomal protein S14 | -0.0272512 |
| WDR45B | WD repeat domain 45B | -0.0271145 |
| RPL38 | ribosomal protein L38 | -0.0269266 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0266449 |
| MKI67 | marker of proliferation Ki-67 | -0.0265186 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.026496 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260033 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0259888 |
| ZFP64 | ZFP64 zinc finger protein | -0.0257957 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0257594 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | -0.0257377 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0255661 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0255606 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | -0.0252635 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0251832 |
| RPL22L1 | ribosomal protein L22-like 1 | -0.0244632 |
| RPL36A | ribosomal protein L36a | -0.0240823 |
| ZNF217 | zinc finger protein 217 | -0.0239255 |
| ENO1 | enolase 1, (alpha) | -0.0239208 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.023901 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0239001 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0238447 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0236774 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0228202 |
