| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.13207 |
| NAV1 | neuron navigator 1 | 0.0920726 |
| FMN1 | formin 1 | 0.0909373 |
| SETBP1 | SET binding protein 1 | 0.0815562 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.069412 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0687199 |
| SRPK2 | SRSF protein kinase 2 | 0.0640852 |
| NAV2 | neuron navigator 2 | 0.0632646 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0615782 |
| MED13L | mediator complex subunit 13-like | 0.0611367 |
| ASPH | aspartate beta-hydroxylase | 0.0610167 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0597643 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0569691 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0555025 |
| CD44 | CD44 molecule (Indian blood group) | 0.0535435 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.053418 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.052443 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0508219 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0501146 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0496702 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0493525 |
| PTK2 | protein tyrosine kinase 2 | 0.0485474 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0484462 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0479195 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0472555 |
| MTPN | myotrophin | 0.0472018 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0457901 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0452199 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0437479 |
| AHNAK | AHNAK nucleoprotein | 0.0433043 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0431567 |
| TMEM178B | transmembrane protein 178B | 0.0429044 |
| CDC73 | cell division cycle 73 | 0.0423667 |
| MYOF | myoferlin | 0.0418723 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.041205 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0408096 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0406121 |
| ANO6 | anoctamin 6 | 0.0405334 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0395064 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0384294 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0382231 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0378592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.037391 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0373859 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.037061 |
| BBX | bobby sox homolog (Drosophila) | 0.0369523 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0368884 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0366022 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0365149 |
| NDRG1 | N-myc downstream regulated 1 | 0.0364821 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0363649 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0360174 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0355354 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0354117 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0352958 |
| NHSL1 | NHS-like 1 | 0.035281 |
| RTN4 | reticulon 4 | 0.0351169 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0348757 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0347602 |
| CUL3 | cullin 3 | 0.0346655 |
| MRTFA | myocardin related transcription factor A | 0.0343365 |
| SMAD3 | SMAD family member 3 | 0.0341321 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0340329 |
| CLIC4 | chloride intracellular channel 4 | 0.0339553 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0339083 |
| ACTN1 | actinin, alpha 1 | 0.0329954 |
| APP | amyloid beta (A4) precursor protein | 0.0327648 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0326617 |
| DST | dystonin | 0.0325488 |
| AFDN | afadin, adherens junction formation factor | 0.0319772 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0318019 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0317639 |
| YAP1 | Yes-associated protein 1 | 0.0316512 |
| GPHN | gephyrin | 0.0316135 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0308449 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0306709 |
| FAT1 | FAT atypical cadherin 1 | 0.0306055 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0305139 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0303944 |
| TXNRD1 | thioredoxin reductase 1 | 0.0302766 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302215 |
| ANXA2 | annexin A2 | 0.0302037 |
| VMP1 | vacuole membrane protein 1 | 0.0300254 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0293445 |
| ARRDC3 | arrestin domain containing 3 | 0.0290827 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0290095 |
| RNF145 | ring finger protein 145 | 0.0277291 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0277239 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0276999 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0275523 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0275496 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0273581 |
| ATXN1 | ataxin 1 | 0.0272255 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0272203 |
| TCF12 | transcription factor 12 | 0.027212 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0272114 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0270393 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0270191 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0270053 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0264468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.132433 |
| NLGN1 | neuroligin 1 | -0.130836 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.129552 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.127196 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.115526 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.105371 |
| VGF | VGF nerve growth factor inducible | -0.103975 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0916408 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0867104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0738711 |
| VIM | vimentin | -0.0673477 |
| PRELID2 | PRELI domain containing 2 | -0.0636635 |
| HLA-B | major histocompatibility complex, class I, B | -0.0617588 |
| MACROD2 | MACRO domain containing 2 | -0.0596189 |
| S100A6 | S100 calcium binding protein A6 | -0.058481 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.054915 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0535627 |
| TMSB10 | thymosin beta 10 | -0.0476734 |
| GDF15 | growth differentiation factor 15 | -0.0428102 |
| FRMD4A | FERM domain containing 4A | -0.042161 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0407457 |
| OXR1 | oxidation resistance 1 | -0.0387678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0380456 |
| TRIM2 | tripartite motif containing 2 | -0.0368212 |
| PTMA | prothymosin, alpha | -0.0363007 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0361613 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.035405 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0353266 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0347445 |
| PGK1 | phosphoglycerate kinase 1 | -0.0322432 |
| SCFD2 | sec1 family domain containing 2 | -0.0313835 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0307905 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0305767 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0303188 |
| CANX | calnexin | -0.0284731 |
| ENO1 | enolase 1, (alpha) | -0.0273267 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0269428 |
| ITGB8 | integrin, beta 8 | -0.0268521 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0267402 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0255315 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0242248 |
| CTSD | cathepsin D | -0.0242163 |
| CALU | calumenin | -0.0239119 |
| CALR | calreticulin | -0.0227291 |
| ACTG1 | actin gamma 1 | -0.0224536 |
| PTCHD4 | patched domain containing 4 | -0.0219842 |
| NEGR1 | neuronal growth regulator 1 | -0.0219099 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0215728 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.021351 |
| RPS8 | ribosomal protein S8 | -0.0213322 |
| HIP1 | huntingtin interacting protein 1 | -0.020882 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0206663 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0205846 |
| FHIT | fragile histidine triad | -0.0205754 |
| PARVB | parvin, beta | -0.0205373 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0205285 |
| RPL35A | ribosomal protein L35a | -0.0200099 |
| FTL | ferritin, light polypeptide | -0.0199484 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.019668 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0194579 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0194302 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0192932 |
| GHR | growth hormone receptor | -0.0188602 |
| GNAS | GNAS complex locus | -0.0188501 |
| HLA-A | major histocompatibility complex, class I, A | -0.0188437 |
| C10ORF90 | chromosome 10 open reading frame 90 | -0.0188037 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0187171 |
| HLA-E | major histocompatibility complex, class I, E | -0.018615 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0184582 |
| INSIG1 | insulin induced gene 1 | -0.0182737 |
| RPS24 | ribosomal protein S24 | -0.0181862 |
| RPLP1 | ribosomal protein, large, P1 | -0.018113 |
| RPL34 | ribosomal protein L34 | -0.018094 |
| DCT | dopachrome tautomerase | -0.0179648 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0179304 |
| PYGB | phosphorylase, glycogen; brain | -0.0175778 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0173334 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0169243 |
| NPR2 | natriuretic peptide receptor 2 | -0.0167611 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0164245 |
| RNF213 | ring finger protein 213 | -0.016365 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0163074 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.01626 |
| HMCN1 | hemicentin 1 | -0.0162451 |
| S100A9 | S100 calcium binding protein A9 | -0.0162387 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0162278 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0161137 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0159974 |
| RAD51B | RAD51 paralog B | -0.0158901 |
| CD109 | CD109 molecule | -0.0158433 |
| HMGA2 | high mobility group AT-hook 2 | -0.0158153 |
| TPI1 | triosephosphate isomerase 1 | -0.0156117 |
| EGR1 | early growth response 1 | -0.0154732 |
| STXBP1 | syntaxin binding protein 1 | -0.0152735 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0152696 |
| GPR155 | G protein-coupled receptor 155 | -0.015114 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0149723 |
| FAM162A | family with sequence similarity 162, member A | -0.0149111 |
| TMEM263 | transmembrane protein 263 | -0.0147723 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0147468 |
