| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.218367 |
| B2M | beta-2-microglobulin | 0.174097 |
| LMO7 | LIM domain 7 | 0.162178 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.14075 |
| INTS6 | integrator complex subunit 6 | 0.130293 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.128281 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.119903 |
| RPS6 | ribosomal protein S6 | 0.102612 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0895283 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0861719 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0838419 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0833141 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0822383 |
| FTL | ferritin, light polypeptide | 0.0814177 |
| GOLGB1 | golgin B1 | 0.0796105 |
| CANX | calnexin | 0.0792686 |
| SMAD3 | SMAD family member 3 | 0.0748408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0738989 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0733855 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0716806 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0709286 |
| RRBP1 | ribosome binding protein 1 | 0.068164 |
| FAT1 | FAT atypical cadherin 1 | 0.0673436 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0663332 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0643002 |
| TMC5 | transmembrane channel-like 5 | 0.062966 |
| EFNB2 | ephrin-B2 | 0.061898 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.060046 |
| PHF3 | PHD finger protein 3 | 0.0599064 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0595721 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0582217 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0551048 |
| AHI1 | Abelson helper integration site 1 | 0.0542455 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0505944 |
| RPL19 | ribosomal protein L19 | 0.0502266 |
| GOLGA4 | golgin A4 | 0.0493031 |
| RPS3 | ribosomal protein S3 | 0.0473407 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.047334 |
| ANXA2 | annexin A2 | 0.0470243 |
| PKM | pyruvate kinase, muscle | 0.0469853 |
| DST | dystonin | 0.0464 |
| DSTN | destrin (actin depolymerizing factor) | 0.0452921 |
| RPL37A | ribosomal protein L37a | 0.0446624 |
| RPL26 | ribosomal protein L26 | 0.0446103 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0442008 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.043007 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0419123 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0418157 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0413311 |
| RPS12 | ribosomal protein S12 | 0.041197 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400566 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0396225 |
| IER3 | immediate early response 3 | 0.0394479 |
| RPS8 | ribosomal protein S8 | 0.0390587 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0390158 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0386531 |
| RPL11 | ribosomal protein L11 | 0.0385913 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0383831 |
| RPL12 | ribosomal protein L12 | 0.0383538 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0373019 |
| HLA-B | major histocompatibility complex, class I, B | 0.0369809 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0368284 |
| RPS27 | ribosomal protein S27 | 0.0364017 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0361589 |
| RPS13 | ribosomal protein S13 | 0.0360485 |
| KYNU | kynureninase | 0.0359269 |
| TPR | translocated promoter region, nuclear basket protein | 0.0356552 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0351854 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0351414 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0348075 |
| ENO1 | enolase 1, (alpha) | 0.0342418 |
| VEGFA | vascular endothelial growth factor A | 0.0340944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0337386 |
| COG6 | component of oligomeric golgi complex 6 | 0.0336247 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0336199 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0333303 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0333124 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0329696 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0329071 |
| HM13 | histocompatibility (minor) 13 | 0.0328506 |
| MT2A | metallothionein 2A | 0.0322629 |
| RPS29 | ribosomal protein S29 | 0.0319333 |
| HKDC1 | hexokinase domain containing 1 | 0.0319331 |
| RPS19 | ribosomal protein S19 | 0.0318635 |
| RPL7A | ribosomal protein L7a | 0.0317327 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0316499 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0313107 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.03126 |
| RPL37 | ribosomal protein L37 | 0.0311652 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.031081 |
| PLSCR2 | phospholipid scramblase 2 | 0.0310295 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0308115 |
| RPL23 | ribosomal protein L23 | 0.0307499 |
| CALR | calreticulin | 0.0303709 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.030334 |
| RPS17 | ribosomal protein S17 | 0.0302554 |
| RACK1 | receptor for activated C kinase 1 | 0.0302483 |
| CALU | calumenin | 0.0300358 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0298483 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0294663 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.124593 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.089959 |
| LYZ | lysozyme | -0.0841653 |
| EGR1 | early growth response 1 | -0.0704711 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0691894 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0643441 |
| NPSR1 | neuropeptide S receptor 1 | -0.0623801 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0580134 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0571376 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0501241 |
| ERBIN | erbb2 interacting protein | -0.049781 |
| PLSCR1 | phospholipid scramblase 1 | -0.0497379 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.039982 |
| TXNIP | thioredoxin interacting protein | -0.0391428 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0390369 |
| CCNL1 | cyclin L1 | -0.0334412 |
| PRKCA | protein kinase C, alpha | -0.031585 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0304139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303927 |
| MX2 | MX dynamin-like GTPase 2 | -0.0303589 |
| HLA-E | major histocompatibility complex, class I, E | -0.0301453 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0294725 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0291902 |
| RIGI | RNA sensor RIG-I | -0.0287377 |
| BCL2L1 | BCL2-like 1 | -0.0277769 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0273699 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0267984 |
| PMP22 | peripheral myelin protein 22 | -0.0266754 |
| ALPK1 | alpha-kinase 1 | -0.025711 |
| KLF6 | Kruppel-like factor 6 | -0.0247819 |
| OXSR1 | oxidative stress responsive 1 | -0.0245795 |
| ZNF148 | zinc finger protein 148 | -0.0243717 |
| TMEM62 | transmembrane protein 62 | -0.0242205 |
| CTSD | cathepsin D | -0.0236761 |
| MSI2 | musashi RNA-binding protein 2 | -0.0235982 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0234468 |
| PERP | PERP, TP53 apoptosis effector | -0.0231974 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0229186 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0227359 |
| ATP10B | ATPase, class V, type 10B | -0.0225131 |
| DIAPH3 | diaphanous-related formin 3 | -0.0223554 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0220666 |
| XAF1 | XIAP associated factor 1 | -0.0220482 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0220331 |
| VCL | vinculin | -0.0216483 |
| TNS4 | tensin 4 | -0.021164 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0210788 |
| HMGB1 | high mobility group box 1 | -0.0209864 |
| NAV1 | neuron navigator 1 | -0.0209624 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0208698 |
| NCKAP5 | NCK-associated protein 5 | -0.0205864 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0205567 |
| S100A6 | S100 calcium binding protein A6 | -0.020505 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0200245 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0200098 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0198587 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0194355 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0193784 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0193691 |
| H1-0 | H1.0 linker histone | -0.0192111 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0192045 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0190641 |
| MMP7 | matrix metallopeptidase 7 | -0.0190503 |
| ANXA3 | annexin A3 | -0.0190395 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0186341 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0186146 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0185843 |
| ITGA6 | integrin, alpha 6 | -0.0185166 |
| KRT19 | keratin 19, type I | -0.0184248 |
| FOSL2 | FOS-like antigen 2 | -0.0184075 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0183987 |
| LAMA4 | laminin, alpha 4 | -0.0183859 |
| FOSL1 | FOS-like antigen 1 | -0.0183843 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0182833 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0179993 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0179437 |
| UBAC2 | UBA domain containing 2 | -0.0179215 |
| IL6ST | interleukin 6 signal transducer | -0.0173694 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0171487 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0171453 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0171226 |
| EFHD2 | EF-hand domain family, member D2 | -0.0171136 |
| CDC42 | cell division cycle 42 | -0.0169689 |
| PTEN | phosphatase and tensin homolog | -0.0169316 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0167805 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.01663 |
| PTK2 | protein tyrosine kinase 2 | -0.0165993 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.016518 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0163157 |
| MECOM | MDS1 and EVI1 complex locus | -0.0163132 |
| PTMA | prothymosin, alpha | -0.0162627 |
| FBXO9 | F-box protein 9 | -0.0160592 |
| FBXO34 | F-box protein 34 | -0.0160572 |
| PHF11 | PHD finger protein 11 | -0.0160413 |
| ETNK1 | ethanolamine kinase 1 | -0.0160131 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0157009 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.015686 |
| APOL6 | apolipoprotein L, 6 | -0.0156127 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | -0.0155711 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0153344 |
