| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.177352 |
| EXT1 | exostosin glycosyltransferase 1 | 0.168734 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.145403 |
| SMAD3 | SMAD family member 3 | 0.143321 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.122102 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.118511 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.113887 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0974533 |
| TJP1 | tight junction protein 1 | 0.0926408 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0921375 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0750992 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0726603 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0711353 |
| KRT20 | keratin 20, type I | 0.069479 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0690899 |
| LAMA4 | laminin, alpha 4 | 0.0661876 |
| MYO1E | myosin IE | 0.0644821 |
| KRT18 | keratin 18, type I | 0.0636309 |
| RPS3 | ribosomal protein S3 | 0.0610876 |
| INTS6 | integrator complex subunit 6 | 0.0592393 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0587824 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0579998 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0575511 |
| NTN4 | netrin 4 | 0.0570625 |
| FAT1 | FAT atypical cadherin 1 | 0.0569737 |
| RPS6 | ribosomal protein S6 | 0.0560341 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0552497 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0548408 |
| CTBP2 | C-terminal binding protein 2 | 0.0539717 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.053962 |
| B2M | beta-2-microglobulin | 0.0534967 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0517426 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0516622 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0506785 |
| PLK2 | polo-like kinase 2 | 0.0503402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0498932 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0496198 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0493736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0492447 |
| RPS12 | ribosomal protein S12 | 0.0489052 |
| TRIB1 | tribbles pseudokinase 1 | 0.0488903 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0488698 |
| DST | dystonin | 0.0484642 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0475003 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0472438 |
| VMP1 | vacuole membrane protein 1 | 0.0454648 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.044914 |
| ETV6 | ets variant 6 | 0.0447567 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0441227 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0439209 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.04292 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0426317 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0413784 |
| KRT8 | keratin 8, type II | 0.0410853 |
| MYO5B | myosin VB | 0.0404824 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.040346 |
| SGMS2 | sphingomyelin synthase 2 | 0.0401089 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0400681 |
| PRR5L | proline rich 5 like | 0.0393291 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0383982 |
| EGR1 | early growth response 1 | 0.0380047 |
| AREG | amphiregulin | 0.0376808 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0376596 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0373039 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0364198 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0363369 |
| RNF213 | ring finger protein 213 | 0.0362534 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0359563 |
| PDZD8 | PDZ domain containing 8 | 0.0358155 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0356051 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0353246 |
| RPS17 | ribosomal protein S17 | 0.0346057 |
| POF1B | premature ovarian failure, 1B | 0.034475 |
| TMC5 | transmembrane channel-like 5 | 0.0343574 |
| VCL | vinculin | 0.0339326 |
| VEGFA | vascular endothelial growth factor A | 0.0337008 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0331334 |
| RPL23 | ribosomal protein L23 | 0.0329464 |
| ATXN1 | ataxin 1 | 0.0328885 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0328423 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0325135 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0325014 |
| MCL1 | myeloid cell leukemia 1 | 0.0323657 |
| BCL2L1 | BCL2-like 1 | 0.0323435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0321732 |
| EGFR | epidermal growth factor receptor | 0.031995 |
| RPS19 | ribosomal protein S19 | 0.0316693 |
| POTEF | POTE ankyrin domain family, member F | 0.0316587 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0313585 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0312749 |
| SIK3 | SIK family kinase 3 | 0.0312443 |
| FOXO1 | forkhead box O1 | 0.0311177 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0303886 |
| RASEF | RAS and EF-hand domain containing | 0.0302727 |
| TMEM65 | transmembrane protein 65 | 0.0302629 |
| GOLGB1 | golgin B1 | 0.0301784 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0301265 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0300281 |
| UTRN | utrophin | 0.0298128 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0294949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101501 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0805088 |
| NDRG1 | N-myc downstream regulated 1 | -0.046356 |
| TXNRD1 | thioredoxin reductase 1 | -0.0374386 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0368644 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356695 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0355897 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0349029 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0345932 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0312011 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0307291 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0295026 |
| GOLGA4 | golgin A4 | -0.0292062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0268058 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0258751 |
| OGA | O-GlcNAcase | -0.0258466 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0255275 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0230162 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0219895 |
| COG5 | component of oligomeric golgi complex 5 | -0.0219707 |
| PTMA | prothymosin, alpha | -0.0211155 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0208758 |
| HDLBP | high density lipoprotein binding protein | -0.0208382 |
| FAM13A | family with sequence similarity 13, member A | -0.0204456 |
| USP3 | ubiquitin specific peptidase 3 | -0.0202475 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0199025 |
| MORF4L2 | mortality factor 4 like 2 | -0.0197686 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0194858 |
| H1-0 | H1.0 linker histone | -0.0193728 |
| TPD52 | tumor protein D52 | -0.0185574 |
| AGR2 | anterior gradient 2 | -0.0182858 |
| HMGB1 | high mobility group box 1 | -0.0181216 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.017937 |
| CANX | calnexin | -0.0174317 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0171228 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0169714 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.016806 |
| TMEM41B | transmembrane protein 41B | -0.0158909 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0158629 |
| S100A6 | S100 calcium binding protein A6 | -0.015668 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0156581 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0156182 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0155575 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0154508 |
| RTN3 | reticulon 3 | -0.0153851 |
| ANLN | anillin, actin binding protein | -0.0153264 |
| GNAS | GNAS complex locus | -0.0151469 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0149788 |
| SEC24D | SEC24 family member D | -0.0148946 |
| WASF2 | WAS protein family, member 2 | -0.014872 |
| HM13 | histocompatibility (minor) 13 | -0.0148332 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0147861 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0146832 |
| CEP95 | centrosomal protein 95kDa | -0.0145667 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0143536 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0141861 |
| JMY | junction mediating and regulatory protein, p53 cofactor | -0.0137254 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0135263 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0135242 |
| LYZ | lysozyme | -0.0134422 |
| CENPF | centromere protein F, 350/400kDa | -0.0133857 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0133512 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0133147 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0130903 |
| HMGB2 | high mobility group box 2 | -0.0130693 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0129446 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0129206 |
| FANCI | Fanconi anemia, complementation group I | -0.0128791 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0128753 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0128736 |
| FAM162A | family with sequence similarity 162, member A | -0.0128083 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.012754 |
| MKI67 | marker of proliferation Ki-67 | -0.0126842 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0125972 |
| FAM135A | family with sequence similarity 135, member A | -0.0125769 |
| SEPTIN2 | septin 2 | -0.0123647 |
| SRP54 | signal recognition particle 54kDa | -0.0123275 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.012294 |
| CALU | calumenin | -0.0122815 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0121497 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0121232 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.012094 |
| FBXO42 | F-box protein 42 | -0.012052 |
| NFIA | nuclear factor I/A | -0.0120449 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0120375 |
| NBAS | neuroblastoma amplified sequence | -0.012006 |
| MZT1 | mitotic spindle organizing protein 1 | -0.0119566 |
| KLHL24 | kelch-like family member 24 | -0.0119272 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0118079 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0117994 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0117827 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.011759 |
| NBEAL1 | neurobeachin-like 1 | -0.0117558 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0116714 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0115806 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | -0.0114988 |
| TMEM165 | transmembrane protein 165 | -0.0114277 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0114125 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0113958 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0112998 |
