| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.172619 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.168411 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.119181 |
| B2M | beta-2-microglobulin | 0.0942216 |
| TMC5 | transmembrane channel-like 5 | 0.0853039 |
| ANXA2 | annexin A2 | 0.0843444 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0728514 |
| RNF213 | ring finger protein 213 | 0.0712613 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0696807 |
| MYOF | myoferlin | 0.0689173 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0682523 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0664552 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0634098 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0629168 |
| SMAD3 | SMAD family member 3 | 0.062613 |
| GDA | guanine deaminase | 0.0603036 |
| VMP1 | vacuole membrane protein 1 | 0.0593255 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0581524 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0568371 |
| FAT1 | FAT atypical cadherin 1 | 0.0560955 |
| DSPP | dentin sialophosphoprotein | 0.0531746 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0507997 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0500076 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0499618 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0483433 |
| DST | dystonin | 0.0475623 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0471585 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0464523 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0446176 |
| VEGFA | vascular endothelial growth factor A | 0.0442479 |
| CLDN4 | claudin 4 | 0.0439697 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.043869 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0437253 |
| CD2AP | CD2-associated protein | 0.043668 |
| SEPTIN9 | septin 9 | 0.0428623 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0421903 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0418614 |
| TXNRD1 | thioredoxin reductase 1 | 0.0407873 |
| EZR | ezrin | 0.0406142 |
| ANXA1 | annexin A1 | 0.0400678 |
| RBM47 | RNA binding motif protein 47 | 0.0399442 |
| TJP1 | tight junction protein 1 | 0.0397133 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0391406 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0390733 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0389973 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0372389 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0365199 |
| SHROOM3 | shroom family member 3 | 0.0358276 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0357039 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0356185 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0351086 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0348223 |
| HDAC9 | histone deacetylase 9 | 0.034519 |
| KRT19 | keratin 19, type I | 0.0342964 |
| MCU | mitochondrial calcium uniporter | 0.0341555 |
| POTEF | POTE ankyrin domain family, member F | 0.0335933 |
| SLTM | SAFB-like, transcription modulator | 0.0333676 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0333363 |
| HYOU1 | hypoxia up-regulated 1 | 0.0327492 |
| AHR | aryl hydrocarbon receptor | 0.0323393 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0322101 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0320018 |
| TXNIP | thioredoxin interacting protein | 0.0314268 |
| RASEF | RAS and EF-hand domain containing | 0.0308342 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0302427 |
| SGMS2 | sphingomyelin synthase 2 | 0.02924 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0291606 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0291142 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0288618 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0286511 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0285561 |
| ITGA6 | integrin, alpha 6 | 0.0285458 |
| AFDN | afadin, adherens junction formation factor | 0.0281192 |
| KRT18 | keratin 18, type I | 0.0280531 |
| TMEM45B | transmembrane protein 45B | 0.0279371 |
| ANXA11 | annexin A11 | 0.0278752 |
| SIK3 | SIK family kinase 3 | 0.0274382 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0273486 |
| TSPAN3 | tetraspanin 3 | 0.0272739 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0268239 |
| PLEC | plectin | 0.0266687 |
| EXPH5 | exophilin 5 | 0.0266424 |
| LIPH | lipase, member H | 0.0264089 |
| PLS1 | plastin 1 | 0.0258989 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0254686 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0254515 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0254461 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0253044 |
| LIMA1 | LIM domain and actin binding 1 | 0.0251951 |
| RPS3 | ribosomal protein S3 | 0.024948 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0246648 |
| ZNF292 | zinc finger protein 292 | 0.024478 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0243981 |
| STK24 | serine/threonine kinase 24 | 0.0243439 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0240939 |
| COBL | cordon-bleu WH2 repeat protein | 0.0240117 |
| AGR3 | anterior gradient 3 | 0.0239752 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0235959 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0233197 |
| SET | SET nuclear proto-oncogene | 0.0232361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.360619 |
| NPSR1 | neuropeptide S receptor 1 | -0.177566 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.13447 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124679 |
| PTMA | prothymosin, alpha | -0.100823 |
| AGR2 | anterior gradient 2 | -0.0864725 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.071669 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0695925 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0549462 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0526298 |
| TMEM123 | transmembrane protein 123 | -0.0498391 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0489525 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0472369 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0455073 |
| RPLP1 | ribosomal protein, large, P1 | -0.0451258 |
| S100A6 | S100 calcium binding protein A6 | -0.0418701 |
| HM13 | histocompatibility (minor) 13 | -0.0399096 |
| KLHL29 | kelch-like family member 29 | -0.0396738 |
| RPL34 | ribosomal protein L34 | -0.0388886 |
| RPS24 | ribosomal protein S24 | -0.038186 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.037864 |
| RPL35A | ribosomal protein L35a | -0.037587 |
| TMSB10 | thymosin beta 10 | -0.0359031 |
| GNAS | GNAS complex locus | -0.0343203 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0339219 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0333042 |
| TES | testin LIM domain protein | -0.0331252 |
| WDR45B | WD repeat domain 45B | -0.0329087 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0328302 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0319817 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0318054 |
| EHBP1 | EH domain binding protein 1 | -0.0317405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0311383 |
| CAPN8 | calpain 8 | -0.0309977 |
| FTL | ferritin, light polypeptide | -0.0303289 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0302889 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0301284 |
| CANX | calnexin | -0.0300312 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297267 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0296028 |
| HDLBP | high density lipoprotein binding protein | -0.0291647 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0283751 |
| CCND1 | cyclin D1 | -0.0282624 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0282379 |
| ATF5 | activating transcription factor 5 | -0.0281339 |
| HMGB1 | high mobility group box 1 | -0.0278642 |
| RPL23 | ribosomal protein L23 | -0.0278435 |
| H1-0 | H1.0 linker histone | -0.0274022 |
| RTN3 | reticulon 3 | -0.0270859 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0267591 |
| PGK1 | phosphoglycerate kinase 1 | -0.0262097 |
| MORF4L2 | mortality factor 4 like 2 | -0.0262016 |
| RAD51B | RAD51 paralog B | -0.025871 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0258637 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0245704 |
| NDRG1 | N-myc downstream regulated 1 | -0.0245646 |
| HLA-E | major histocompatibility complex, class I, E | -0.0244431 |
| TFRC | transferrin receptor | -0.0238813 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0237499 |
| AREG | amphiregulin | -0.0231931 |
| RPS21 | ribosomal protein S21 | -0.0231713 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0231561 |
| ATXN1 | ataxin 1 | -0.0229636 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0228931 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0228398 |
| RPL12 | ribosomal protein L12 | -0.0227623 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0225718 |
| DEK | DEK proto-oncogene | -0.0218444 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.021694 |
| RPS25 | ribosomal protein S25 | -0.0215203 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.0215116 |
| TPM4 | tropomyosin 4 | -0.0213423 |
| RPS8 | ribosomal protein S8 | -0.0211816 |
| RPL38 | ribosomal protein L38 | -0.0210337 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.021023 |
| GLG1 | golgi glycoprotein 1 | -0.0207012 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0206722 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.020479 |
| CUX1 | cut-like homeobox 1 | -0.0201202 |
| ANLN | anillin, actin binding protein | -0.0200817 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0200625 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.019568 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0194807 |
| PYGB | phosphorylase, glycogen; brain | -0.0194381 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0191292 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0190965 |
| S100A10 | S100 calcium binding protein A10 | -0.0187674 |
| SRPRA | SRP receptor subunit alpha | -0.0187435 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0187059 |
| RPL39 | ribosomal protein L39 | -0.0186269 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0185898 |
| FBXO11 | F-box protein 11 | -0.0184616 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0183227 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0180041 |
| IER3 | immediate early response 3 | -0.0177929 |
| VCL | vinculin | -0.0176769 |
| HLA-C | major histocompatibility complex, class I, C | -0.0176469 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0176244 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.017595 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0175873 |
