| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.135224 |
| LMO7 | LIM domain 7 | 0.126869 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.108123 |
| FAT1 | FAT atypical cadherin 1 | 0.103916 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.103317 |
| RPS6 | ribosomal protein S6 | 0.102052 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0922112 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0893674 |
| MUC13 | mucin 13, cell surface associated | 0.0870467 |
| VEGFA | vascular endothelial growth factor A | 0.0834042 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0739382 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0677527 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0669862 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0646538 |
| MYO1E | myosin IE | 0.0616799 |
| RPS12 | ribosomal protein S12 | 0.0606506 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0584153 |
| NEBL | nebulette | 0.0560345 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0546888 |
| RPL26 | ribosomal protein L26 | 0.0524895 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.051886 |
| RBM25 | RNA binding motif protein 25 | 0.0499648 |
| RPS3 | ribosomal protein S3 | 0.049649 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0495034 |
| GOLGA4 | golgin A4 | 0.0493779 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0473322 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0449309 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0446644 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433153 |
| JMJD1C | jumonji domain containing 1C | 0.0432798 |
| AREG | amphiregulin | 0.0431511 |
| B2M | beta-2-microglobulin | 0.0424805 |
| MYO5B | myosin VB | 0.0424239 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0422913 |
| MED13 | mediator complex subunit 13 | 0.0418643 |
| RPL9 | ribosomal protein L9 | 0.0416946 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0415966 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0415087 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0412143 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0401926 |
| RBM39 | RNA binding motif protein 39 | 0.0395858 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0395138 |
| RPS19 | ribosomal protein S19 | 0.0389463 |
| RPL35A | ribosomal protein L35a | 0.0384061 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0380089 |
| RNF145 | ring finger protein 145 | 0.0378933 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.037729 |
| VCL | vinculin | 0.0377022 |
| GOLGB1 | golgin B1 | 0.0375933 |
| RPL37A | ribosomal protein L37a | 0.0372688 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0372174 |
| RPL36 | ribosomal protein L36 | 0.0361355 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0352864 |
| RPL11 | ribosomal protein L11 | 0.0351855 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0349515 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0348091 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.034589 |
| ZNF292 | zinc finger protein 292 | 0.0344588 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0341136 |
| RPS13 | ribosomal protein S13 | 0.0338588 |
| FTL | ferritin, light polypeptide | 0.0335545 |
| SON | SON DNA binding protein | 0.0335487 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0334616 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.03339 |
| SNX9 | sorting nexin 9 | 0.0328727 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0327278 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0326913 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0324746 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0324236 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0322916 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0322455 |
| FOXP1 | forkhead box P1 | 0.0321499 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0320733 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0319157 |
| USP53 | ubiquitin specific peptidase 53 | 0.0318546 |
| ZNF638 | zinc finger protein 638 | 0.0318493 |
| RPLP2 | ribosomal protein, large, P2 | 0.0316463 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0313011 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0311199 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0309278 |
| CALR | calreticulin | 0.0304915 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0303348 |
| ZNF644 | zinc finger protein 644 | 0.0302654 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0302485 |
| SHROOM3 | shroom family member 3 | 0.0301925 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.030058 |
| CD44 | CD44 molecule (Indian blood group) | 0.0299523 |
| MATR3 | matrin 3 | 0.029831 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0291994 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0291524 |
| CTBP2 | C-terminal binding protein 2 | 0.0290387 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0285774 |
| TJP1 | tight junction protein 1 | 0.0284174 |
| VMP1 | vacuole membrane protein 1 | 0.0284063 |
| NEK7 | NIMA-related kinase 7 | 0.0281236 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0280951 |
| RPS17 | ribosomal protein S17 | 0.0279595 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0279493 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0279049 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0278873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.187331 |
| PTMA | prothymosin, alpha | -0.130529 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.10172 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0849229 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.061356 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0601202 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0490238 |
| S100A6 | S100 calcium binding protein A6 | -0.0473405 |
| KLF10 | Kruppel-like factor 10 | -0.0448067 |
| FOSL1 | FOS-like antigen 1 | -0.0404548 |
| MUC17 | mucin 17, cell surface associated | -0.0402643 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0392735 |
| ACTG1 | actin gamma 1 | -0.0389114 |
| HMGA1 | high mobility group AT-hook 1 | -0.038281 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0378291 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.036898 |
| PGK1 | phosphoglycerate kinase 1 | -0.0366689 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0366621 |
| RNF217 | ring finger protein 217 | -0.0353666 |
| FLNB | filamin B, beta | -0.0346874 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0335843 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0334946 |
| FERMT1 | fermitin family member 1 | -0.0331819 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0329501 |
| CALB1 | calbindin 1, 28kDa | -0.0323271 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0320273 |
| POTEF | POTE ankyrin domain family, member F | -0.0319322 |
| KRT18 | keratin 18, type I | -0.0307273 |
| TPM4 | tropomyosin 4 | -0.0299535 |
| H1-0 | H1.0 linker histone | -0.0291016 |
| DIAPH3 | diaphanous-related formin 3 | -0.028294 |
| CENPF | centromere protein F, 350/400kDa | -0.027766 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0270908 |
| TUBA1B | tubulin, alpha 1b | -0.0262636 |
| ITGB4 | integrin, beta 4 | -0.0259467 |
| AHNAK | AHNAK nucleoprotein | -0.0257712 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0248579 |
| TMEM123 | transmembrane protein 123 | -0.0245793 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0242919 |
| LDHA | lactate dehydrogenase A | -0.0239682 |
| PKM | pyruvate kinase, muscle | -0.0237592 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0234165 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0230647 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0222688 |
| KRT19 | keratin 19, type I | -0.0221754 |
| EHBP1 | EH domain binding protein 1 | -0.0218753 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0218523 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.021489 |
| IER3 | immediate early response 3 | -0.0211816 |
| ANTXR2 | anthrax toxin receptor 2 | -0.020761 |
| MLEC | malectin | -0.0203078 |
| ANLN | anillin, actin binding protein | -0.0194364 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0193688 |
| KLK10 | kallikrein-related peptidase 10 | -0.0192288 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0186804 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0185577 |
| LSAMP | limbic system-associated membrane protein | -0.0183518 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0182096 |
| TUBB | tubulin, beta class I | -0.0180299 |
| NRN1 | neuritin 1 | -0.0179557 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0175438 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0169256 |
| SMC4 | structural maintenance of chromosomes 4 | -0.016891 |
| PERP | PERP, TP53 apoptosis effector | -0.0168431 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0165482 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0164112 |
| TPX2 | TPX2, microtubule-associated | -0.0163046 |
| CENPE | centromere protein E, 312kDa | -0.0162719 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0160095 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0157316 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0156805 |
| RRM2 | ribonucleotide reductase M2 | -0.0156788 |
| ARRDC3 | arrestin domain containing 3 | -0.0154591 |
| ACTN4 | actinin, alpha 4 | -0.0153446 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0152235 |
| HMGB1 | high mobility group box 1 | -0.0151992 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0151056 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0149512 |
| CLDN7 | claudin 7 | -0.0148396 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0148154 |
| TMSB10 | thymosin beta 10 | -0.0147897 |
| MT1E | metallothionein 1E | -0.01475 |
| TFF1 | trefoil factor 1 | -0.0147054 |
| SH3D19 | SH3 domain containing 19 | -0.0146478 |
| PRELID2 | PRELI domain containing 2 | -0.0144905 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.014194 |
| NBEAL1 | neurobeachin-like 1 | -0.014181 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0140042 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0139666 |
| TNS4 | tensin 4 | -0.0137237 |
| PHGR1 | proline/histidine/glycine-rich 1 | -0.0136413 |
| LAMA4 | laminin, alpha 4 | -0.0129777 |
| MKI67 | marker of proliferation Ki-67 | -0.012966 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0124506 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.012255 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0122045 |
| TAGLN2 | transgelin 2 | -0.0120675 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0120646 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0119979 |
| CSTB | cystatin B (stefin B) | -0.0119739 |
