| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the TAK-901_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.20264 |
| MT2A | metallothionein 2A | 0.196203 |
| GRAMD1B | GRAM domain containing 1B | 0.1634 |
| TXNRD1 | thioredoxin reductase 1 | 0.138281 |
| PM20D1 | peptidase M20 domain containing 1 | 0.120152 |
| FTL | ferritin, light polypeptide | 0.103483 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0944635 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0861539 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0736503 |
| FGB | fibrinogen beta chain | 0.0689582 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0668711 |
| RPL23 | ribosomal protein L23 | 0.0636516 |
| TPM3 | tropomyosin 3 | 0.0609783 |
| RPS6 | ribosomal protein S6 | 0.0581835 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0530268 |
| RPS12 | ribosomal protein S12 | 0.0514202 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0493218 |
| RPL19 | ribosomal protein L19 | 0.0440637 |
| RPL37A | ribosomal protein L37a | 0.0440411 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0438088 |
| B2M | beta-2-microglobulin | 0.0432537 |
| YBX1 | Y box binding protein 1 | 0.0414522 |
| RPS19 | ribosomal protein S19 | 0.0412018 |
| RPS3 | ribosomal protein S3 | 0.0394298 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391325 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0388732 |
| RPL7 | ribosomal protein L7 | 0.0368429 |
| RTN4 | reticulon 4 | 0.0366388 |
| RPS17 | ribosomal protein S17 | 0.0363458 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0362121 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0361088 |
| RPL36 | ribosomal protein L36 | 0.0343498 |
| RPS8 | ribosomal protein S8 | 0.0336538 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0335819 |
| ENO1 | enolase 1, (alpha) | 0.0324581 |
| MATR3 | matrin 3 | 0.0313066 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0302555 |
| RPS29 | ribosomal protein S29 | 0.0298112 |
| RPL11 | ribosomal protein L11 | 0.0291343 |
| RNF145 | ring finger protein 145 | 0.0287616 |
| WDR43 | WD repeat domain 43 | 0.0285178 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0283937 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.028059 |
| RPLP1 | ribosomal protein, large, P1 | 0.0278398 |
| RPL26 | ribosomal protein L26 | 0.0275986 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0273949 |
| PKM | pyruvate kinase, muscle | 0.0269916 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0268827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0264799 |
| RPS27 | ribosomal protein S27 | 0.0257435 |
| USP3 | ubiquitin specific peptidase 3 | 0.0256658 |
| FAM107B | family with sequence similarity 107, member B | 0.0253068 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0252782 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0251109 |
| YBX3 | Y box binding protein 3 | 0.0247617 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0240911 |
| RPS23 | ribosomal protein S23 | 0.0237195 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0237036 |
| KIF5B | kinesin family member 5B | 0.0236413 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0232651 |
| PTMA | prothymosin, alpha | 0.0225542 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0225139 |
| PNN | pinin, desmosome associated protein | 0.0224535 |
| RPL8 | ribosomal protein L8 | 0.022311 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.021875 |
| ZNF292 | zinc finger protein 292 | 0.0218336 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0217716 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0217484 |
| RBM25 | RNA binding motif protein 25 | 0.0217092 |
| RPL3 | ribosomal protein L3 | 0.0214791 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0214775 |
| RPL37 | ribosomal protein L37 | 0.0212963 |
| RPS2 | ribosomal protein S2 | 0.0211485 |
| RPS18 | ribosomal protein S18 | 0.0210167 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0210125 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0209736 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0206 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0205593 |
| RPLP2 | ribosomal protein, large, P2 | 0.0203755 |
| RPL18 | ribosomal protein L18 | 0.0203632 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0203344 |
| PFN1 | profilin 1 | 0.0203306 |
| RPS14 | ribosomal protein S14 | 0.0202947 |
| RPL28 | ribosomal protein L28 | 0.020227 |
| TPI1 | triosephosphate isomerase 1 | 0.0200726 |
| RPS15 | ribosomal protein S15 | 0.0199973 |
| RPS27A | ribosomal protein S27a | 0.0199409 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0199345 |
| RPL32 | ribosomal protein L32 | 0.0197765 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0194167 |
| RPS5 | ribosomal protein S5 | 0.0193218 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0188964 |
| BRD2 | bromodomain containing 2 | 0.0188845 |
| S100A9 | S100 calcium binding protein A9 | 0.0188402 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0186886 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0185737 |
| FAT1 | FAT atypical cadherin 1 | 0.0185118 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0184955 |
| CLU | clusterin | 0.0182775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0182476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.173198 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.155123 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.150506 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0998503 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0965334 |
| PYGL | phosphorylase, glycogen, liver | -0.0915111 |
| ACTG1 | actin gamma 1 | -0.0831532 |
| IGF2 | insulin-like growth factor 2 | -0.0717356 |
| CMIP | c-Maf inducing protein | -0.0694343 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0692168 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0680817 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0648578 |
| DOCK4 | dedicator of cytokinesis 4 | -0.064648 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0644865 |
| OSMR | oncostatin M receptor | -0.0604161 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0579256 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0571324 |
| FMNL2 | formin-like 2 | -0.0541148 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0524691 |
| VCL | vinculin | -0.0510761 |
| EGFR | epidermal growth factor receptor | -0.0510048 |
| EGR1 | early growth response 1 | -0.0490992 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0481061 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0468813 |
| S100A6 | S100 calcium binding protein A6 | -0.0444658 |
| KYNU | kynureninase | -0.0444641 |
| FLNB | filamin B, beta | -0.0436773 |
| CFDP1 | craniofacial development protein 1 | -0.0434421 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0398268 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0398131 |
| ERBIN | erbb2 interacting protein | -0.0392766 |
| BICC1 | BicC family RNA binding protein 1 | -0.0392315 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0389937 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0369231 |
| COPA | coatomer protein complex, subunit alpha | -0.0368515 |
| NAV3 | neuron navigator 3 | -0.0368324 |
| USP34 | ubiquitin specific peptidase 34 | -0.036771 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.036323 |
| TPM4 | tropomyosin 4 | -0.0358224 |
| LDHA | lactate dehydrogenase A | -0.0349826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0348035 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0340859 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0339886 |
| DENND4A | DENN/MADD domain containing 4A | -0.0339653 |
| ACTN1 | actinin, alpha 1 | -0.033651 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0334795 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0334719 |
| PCNX4 | pecanex 4 | -0.0334441 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.032243 |
| NHSL1 | NHS-like 1 | -0.0320229 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0317882 |
| CAVIN1 | caveolae associated protein 1 | -0.0316007 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0314726 |
| TPM1 | tropomyosin 1 (alpha) | -0.0310404 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0308359 |
| EXT1 | exostosin glycosyltransferase 1 | -0.030831 |
| SNX14 | sorting nexin 14 | -0.0306804 |
| DST | dystonin | -0.0306739 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0304853 |
| NUMB | numb homolog (Drosophila) | -0.0300751 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0300034 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0294904 |
| AK1 | adenylate kinase 1 | -0.029455 |
| PATJ | PATJ crumbs cell polarity complex component | -0.029052 |
| EHBP1 | EH domain binding protein 1 | -0.0288198 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0286165 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0284913 |
| ATG7 | autophagy related 7 | -0.02819 |
| HLA-E | major histocompatibility complex, class I, E | -0.0279596 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0278163 |
| NF1 | neurofibromin 1 | -0.0267129 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0265886 |
| CCDC7 | coiled-coil domain containing 7 | -0.0263157 |
| RASAL2 | RAS protein activator like 2 | -0.0258531 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258091 |
| VIM | vimentin | -0.0257827 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0257283 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254511 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0254273 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0251945 |
| HLA-B | major histocompatibility complex, class I, B | -0.0245016 |
| RAD51B | RAD51 paralog B | -0.0243741 |
| MYO1E | myosin IE | -0.0237712 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0234297 |
| MORF4L2 | mortality factor 4 like 2 | -0.0234264 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0233017 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0232352 |
| INTS6 | integrator complex subunit 6 | -0.0232299 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0231082 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0226401 |
| HMGA2 | high mobility group AT-hook 2 | -0.0225988 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0224615 |
| SBF2 | SET binding factor 2 | -0.0222523 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0221962 |
| NEGR1 | neuronal growth regulator 1 | -0.0220504 |
| CDK13 | cyclin-dependent kinase 13 | -0.0220143 |
| CYTH1 | cytohesin 1 | -0.0219784 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0218976 |
| LAMC2 | laminin, gamma 2 | -0.0214212 |
| NLK | nemo-like kinase | -0.0213069 |
