| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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88 genes differentially expressed following the TAK-901_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.224259 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.198984 |
| FAT1 | FAT atypical cadherin 1 | 0.147516 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.138244 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.134113 |
| LDHA | lactate dehydrogenase A | 0.130585 |
| JMJD1C | jumonji domain containing 1C | 0.127482 |
| ASPH | aspartate beta-hydroxylase | 0.117788 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.098459 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0942909 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0883811 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.085482 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0854283 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0790176 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0771108 |
| FOSL1 | FOS-like antigen 1 | 0.0715297 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.068614 |
| RPS12 | ribosomal protein S12 | 0.0661455 |
| INTS6 | integrator complex subunit 6 | 0.0619053 |
| ZNF292 | zinc finger protein 292 | 0.0615215 |
| RPS19 | ribosomal protein S19 | 0.0582972 |
| RPL23 | ribosomal protein L23 | 0.0537312 |
| RBM39 | RNA binding motif protein 39 | 0.0513616 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0499747 |
| PDE10A | phosphodiesterase 10A | 0.0464536 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0463629 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0457362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0397067 |
| ANXA2 | annexin A2 | 0.0380196 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0375511 |
| RPS6 | ribosomal protein S6 | 0.0366029 |
| RLF | rearranged L-myc fusion | 0.0316251 |
| PARD3 | par-3 family cell polarity regulator | 0.0273648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0271803 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246037 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0183747 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0156724 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0115277 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00998967 |
| LMO7 | LIM domain 7 | 0.00887269 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00800125 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.00235762 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.00162944 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0010758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.262077 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.25463 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.172003 |
| FNDC3B | fibronectin type III domain containing 3B | -0.140291 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.130347 |
| TMSB10 | thymosin beta 10 | -0.129668 |
| VIM | vimentin | -0.113594 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.109949 |
| BBX | bobby sox homolog (Drosophila) | -0.108402 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.108388 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0994231 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0982033 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0865448 |
| FN1 | fibronectin 1 | -0.0850373 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0815416 |
| RIGI | RNA sensor RIG-I | -0.0801732 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0742243 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0722914 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0677076 |
| TCF12 | transcription factor 12 | -0.066967 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0643379 |
| CDH13 | cadherin 13 | -0.0595166 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0539582 |
| ARRDC3 | arrestin domain containing 3 | -0.0527379 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0500044 |
| AOPEP | aminopeptidase O (putative) | -0.0460198 |
| APP | amyloid beta (A4) precursor protein | -0.0401077 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0346683 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0306181 |
| B2M | beta-2-microglobulin | -0.0279077 |
| PTMA | prothymosin, alpha | -0.0276611 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255577 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0194673 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0174492 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0160451 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0129161 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.010781 |
| KLF10 | Kruppel-like factor 10 | -0.00931847 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00859412 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0081481 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00755538 |
| CCNL1 | cyclin L1 | -0.00639492 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00149766 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -4.82059E-4 |
