| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.25765 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.162691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.132211 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.125432 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.110366 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.108909 |
| RPS16 | ribosomal protein S16 | 0.108636 |
| FNDC3B | fibronectin type III domain containing 3B | 0.102 |
| FBL | fibrillarin | 0.0962128 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0909214 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0866222 |
| PTMA | prothymosin, alpha | 0.083773 |
| YBX1 | Y box binding protein 1 | 0.0813419 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0762329 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0755451 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.073458 |
| ZFP36 | ZFP36 ring finger protein | 0.0703539 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0677131 |
| RPS3 | ribosomal protein S3 | 0.0677061 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.061011 |
| RPS12 | ribosomal protein S12 | 0.0602377 |
| FMNL2 | formin-like 2 | 0.0569372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0563841 |
| RPS17 | ribosomal protein S17 | 0.0513483 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0510829 |
| VIM | vimentin | 0.0504777 |
| SQSTM1 | sequestosome 1 | 0.0502087 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0494418 |
| PKM | pyruvate kinase, muscle | 0.0488967 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0482266 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0480882 |
| ENO1 | enolase 1, (alpha) | 0.0480503 |
| CTBP2 | C-terminal binding protein 2 | 0.0478819 |
| RPL37A | ribosomal protein L37a | 0.0469565 |
| RACK1 | receptor for activated C kinase 1 | 0.0468782 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0464687 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0463387 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0460443 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0452109 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0451929 |
| VEGFA | vascular endothelial growth factor A | 0.0448051 |
| BRD2 | bromodomain containing 2 | 0.0441621 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0434065 |
| INTS6 | integrator complex subunit 6 | 0.0427894 |
| TPM3 | tropomyosin 3 | 0.042355 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0422013 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0416984 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.041324 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0412766 |
| CENPF | centromere protein F, 350/400kDa | 0.0406138 |
| SFTPA2 | surfactant protein A2 | 0.0403893 |
| RPS6 | ribosomal protein S6 | 0.0402834 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0402593 |
| FTL | ferritin, light polypeptide | 0.0397088 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.038227 |
| PCBP2 | poly(rC) binding protein 2 | 0.0379588 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.037601 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0375496 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0374385 |
| JMJD1C | jumonji domain containing 1C | 0.0372618 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0370288 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0368675 |
| SET | SET nuclear proto-oncogene | 0.036221 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0361393 |
| GOLGB1 | golgin B1 | 0.0359531 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0356976 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0354169 |
| RPS2 | ribosomal protein S2 | 0.0351475 |
| POTEF | POTE ankyrin domain family, member F | 0.0346937 |
| B2M | beta-2-microglobulin | 0.0342708 |
| LDHA | lactate dehydrogenase A | 0.0339842 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0327698 |
| SETD5 | SET domain containing 5 | 0.0327151 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0319339 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0318184 |
| RPLP2 | ribosomal protein, large, P2 | 0.0310157 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0308963 |
| MAP1B | microtubule-associated protein 1B | 0.0308476 |
| RPL11 | ribosomal protein L11 | 0.0306477 |
| PFN1 | profilin 1 | 0.0305169 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0304453 |
| KRT18 | keratin 18, type I | 0.0301995 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0300421 |
| UBAP2 | ubiquitin associated protein 2 | 0.0298084 |
| FLNB | filamin B, beta | 0.0295535 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0294081 |
| NAV2 | neuron navigator 2 | 0.029389 |
| HMGA1 | high mobility group AT-hook 1 | 0.0292031 |
| RPS23 | ribosomal protein S23 | 0.0290427 |
| WDR43 | WD repeat domain 43 | 0.028969 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.028875 |
| GOLGA4 | golgin A4 | 0.0286456 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0286195 |
| SEPTIN9 | septin 9 | 0.0286193 |
| RPL7 | ribosomal protein L7 | 0.0281961 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0281242 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0280174 |
| NUP98 | nucleoporin 98kDa | 0.0277902 |
| RPL26 | ribosomal protein L26 | 0.027632 |
| MSN | moesin | 0.0276101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0696042 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0665341 |
| ACTN4 | actinin, alpha 4 | -0.0584183 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0572268 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0538317 |
| EDN1 | endothelin 1 | -0.0518867 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0503283 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0483164 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0457706 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0404518 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0352345 |
| CAVIN1 | caveolae associated protein 1 | -0.0349685 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0347292 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0330602 |
| FOSL1 | FOS-like antigen 1 | -0.0290582 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0280928 |
| BCL2L1 | BCL2-like 1 | -0.0270247 |
| IER3 | immediate early response 3 | -0.0269843 |
| RPLP1 | ribosomal protein, large, P1 | -0.0267966 |
| RTN4 | reticulon 4 | -0.0254728 |
| TXNRD1 | thioredoxin reductase 1 | -0.0248214 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0247955 |
| KLF6 | Kruppel-like factor 6 | -0.0246413 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0245489 |
| TMEM41B | transmembrane protein 41B | -0.0234238 |
| ZNF780B | zinc finger protein 780B | -0.0231952 |
| VCL | vinculin | -0.022961 |
| KLF10 | Kruppel-like factor 10 | -0.0226736 |
| ZNF546 | zinc finger protein 546 | -0.0226002 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0225858 |
| EGR1 | early growth response 1 | -0.0225128 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0224559 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.022388 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0220176 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0219278 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | -0.021744 |
| EGFR | epidermal growth factor receptor | -0.0214274 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0212698 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0209902 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0194633 |
| TMSB10 | thymosin beta 10 | -0.0191986 |
| RPS24 | ribosomal protein S24 | -0.0191628 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0183756 |
| FHL2 | four and a half LIM domains 2 | -0.0183646 |
| NOCT | nocturnin | -0.0177208 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0175994 |
| SMYD3 | SET and MYND domain containing 3 | -0.0173628 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0172528 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0172008 |
| RNF169 | ring finger protein 169 | -0.0171722 |
| FAT1 | FAT atypical cadherin 1 | -0.0171408 |
| ANLN | anillin, actin binding protein | -0.0171022 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0168061 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0165178 |
| RNF121 | ring finger protein 121 | -0.0164114 |
| ENOSF1 | enolase superfamily member 1 | -0.0163047 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0162227 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0159476 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0159281 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0158464 |
| PGK1 | phosphoglycerate kinase 1 | -0.0155889 |
| STK4 | serine/threonine kinase 4 | -0.0154801 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0154477 |
| RASAL2 | RAS protein activator like 2 | -0.0154285 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.015413 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0153693 |
| ITGB5 | integrin, beta 5 | -0.0153239 |
| PYGB | phosphorylase, glycogen; brain | -0.0149062 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0148795 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0144757 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0143788 |
| RPL34 | ribosomal protein L34 | -0.0143434 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0142401 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0141899 |
| SEPTIN10 | septin 10 | -0.0141765 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0139345 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0138265 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0136398 |
| BMERB1 | bMERB domain containing 1 | -0.0135975 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0135687 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0134667 |
| ZNF217 | zinc finger protein 217 | -0.0132634 |
| CTPS1 | CTP synthase 1 | -0.0131925 |
| RPL6 | ribosomal protein L6 | -0.0128559 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0128175 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.0127542 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0126055 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0123292 |
| FRMD6 | FERM domain containing 6 | -0.012284 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0121455 |
| PLAC8 | placenta-specific 8 | -0.0121044 |
| RGS20 | regulator of G-protein signaling 20 | -0.012091 |
| IL6ST | interleukin 6 signal transducer | -0.0120736 |
| OSMR | oncostatin M receptor | -0.0120182 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.011846 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.011783 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0117827 |
| CD2AP | CD2-associated protein | -0.0117577 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0116477 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.011629 |
