| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.203758 |
| FN1 | fibronectin 1 | 0.168136 |
| VEGFA | vascular endothelial growth factor A | 0.152498 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.139263 |
| VIM | vimentin | 0.114222 |
| NRP1 | neuropilin 1 | 0.0988727 |
| HDAC9 | histone deacetylase 9 | 0.0904518 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0871928 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0845827 |
| LOXL2 | lysyl oxidase-like 2 | 0.0821536 |
| STC1 | stanniocalcin 1 | 0.0807108 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0801378 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0794214 |
| CD44 | CD44 molecule (Indian blood group) | 0.0693736 |
| ANXA2 | annexin A2 | 0.0678229 |
| NAV1 | neuron navigator 1 | 0.0662169 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0653415 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0650212 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0642672 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0641534 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0625962 |
| RPS6 | ribosomal protein S6 | 0.0616469 |
| COL5A1 | collagen, type V, alpha 1 | 0.0612478 |
| RUNX1 | runt-related transcription factor 1 | 0.0608664 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0595065 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0593033 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0590238 |
| MMP12 | matrix metallopeptidase 12 | 0.0585754 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.058067 |
| FRMD4A | FERM domain containing 4A | 0.0570668 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0550011 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.053319 |
| SP100 | SP100 nuclear antigen | 0.0527522 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0521215 |
| ENO1 | enolase 1, (alpha) | 0.0515797 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0513415 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0503892 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.050073 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0496452 |
| FNIP1 | folliculin interacting protein 1 | 0.049295 |
| IFI44L | interferon-induced protein 44-like | 0.0471296 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0470357 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0469496 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0467805 |
| TPM1 | tropomyosin 1 (alpha) | 0.0466383 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0465212 |
| NDRG1 | N-myc downstream regulated 1 | 0.0462965 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0456565 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0454646 |
| MMP2 | matrix metallopeptidase 2 | 0.0446077 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0440271 |
| INHBA | inhibin, beta A | 0.0440094 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0439964 |
| RPS17 | ribosomal protein S17 | 0.0438229 |
| COL5A3 | collagen, type V, alpha 3 | 0.0436914 |
| CDH13 | cadherin 13 | 0.043576 |
| FBXO32 | F-box protein 32 | 0.0435193 |
| RAI14 | retinoic acid induced 14 | 0.0434845 |
| TMEM178B | transmembrane protein 178B | 0.0412003 |
| SMAD3 | SMAD family member 3 | 0.0410604 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.04106 |
| NAV2 | neuron navigator 2 | 0.040948 |
| FAT1 | FAT atypical cadherin 1 | 0.0406825 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0406468 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0399975 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0398439 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0397274 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0396061 |
| ECE1 | endothelin converting enzyme 1 | 0.0392975 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0390784 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0390065 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038506 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0379929 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0377062 |
| EGR1 | early growth response 1 | 0.0376373 |
| TASOR2 | transcription activation suppressor family member 2 | 0.0374107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0372194 |
| CD109 | CD109 molecule | 0.0370597 |
| GOLGB1 | golgin B1 | 0.0364334 |
| DST | dystonin | 0.0363737 |
| LYST | lysosomal trafficking regulator | 0.0356119 |
| MX1 | MX dynamin-like GTPase 1 | 0.0350357 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0350344 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0347357 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0346405 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345306 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0343751 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0342541 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0341309 |
| TOP1 | topoisomerase (DNA) I | 0.0340954 |
| ZNF638 | zinc finger protein 638 | 0.0338687 |
| CALR | calreticulin | 0.0337663 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0334315 |
| FHIT | fragile histidine triad | 0.0331652 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0329976 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0329562 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0319463 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0318899 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0317568 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0316922 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109299 |
| PTMA | prothymosin, alpha | -0.0561068 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0522478 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0493544 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0465462 |
| MT2A | metallothionein 2A | -0.0458068 |
| ANLN | anillin, actin binding protein | -0.0451409 |
| CENPF | centromere protein F, 350/400kDa | -0.0451298 |
| PGK1 | phosphoglycerate kinase 1 | -0.0436959 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358893 |
| TPX2 | TPX2, microtubule-associated | -0.0357879 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0354041 |
| HMGB2 | high mobility group box 2 | -0.0329348 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0301738 |
| MKI67 | marker of proliferation Ki-67 | -0.0292469 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0288658 |
| DIAPH3 | diaphanous-related formin 3 | -0.0282826 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0263816 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0261086 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0259486 |
| S100A6 | S100 calcium binding protein A6 | -0.0245214 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0241064 |
| FAM162A | family with sequence similarity 162, member A | -0.0235295 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0234864 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0230332 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.022823 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226392 |
| SNX14 | sorting nexin 14 | -0.0223619 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0222829 |
| NCOA7 | nuclear receptor coactivator 7 | -0.021923 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0207957 |
| KIF4A | kinesin family member 4A | -0.0201736 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0198962 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0198341 |
| HMGB1 | high mobility group box 1 | -0.0195304 |
| NUP58 | nucleoporin 58 | -0.0194806 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0191893 |
| TTK | TTK protein kinase | -0.0191489 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0191329 |
| CENPE | centromere protein E, 312kDa | -0.0190395 |
| INSIG1 | insulin induced gene 1 | -0.0190125 |
| MT1E | metallothionein 1E | -0.0190048 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0189085 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.0187722 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0186215 |
| XPO1 | exportin 1 | -0.0185692 |
| TMEM39A | transmembrane protein 39A | -0.0183626 |
| KIF20B | kinesin family member 20B | -0.0183042 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0182724 |
| ECT2 | epithelial cell transforming 2 | -0.0181513 |
| SUCO | SUN domain containing ossification factor | -0.0180094 |
| SGO2 | shugoshin 2 | -0.0179805 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0174564 |
| SPAG9 | sperm associated antigen 9 | -0.0173418 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0172763 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0172736 |
| PHIP | pleckstrin homology domain interacting protein | -0.0171623 |
| ZNF292 | zinc finger protein 292 | -0.0170465 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0170342 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0168643 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0165408 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0165338 |
| MORF4L1 | mortality factor 4 like 1 | -0.0165321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0164006 |
| TFG | TRK-fused gene | -0.01635 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0160781 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0156894 |
| CKAP5 | cytoskeleton associated protein 5 | -0.015687 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0155482 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0155347 |
| MORF4L2 | mortality factor 4 like 2 | -0.0154625 |
| SDC4 | syndecan 4 | -0.0152422 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0152162 |
| CD63 | CD63 molecule | -0.0151381 |
| PRR11 | proline rich 11 | -0.015103 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0150845 |
| GOLT1B | golgi transport 1B | -0.0150555 |
| CAVIN1 | caveolae associated protein 1 | -0.0149448 |
| GPSM2 | G-protein signaling modulator 2 | -0.014921 |
| CLINT1 | clathrin interactor 1 | -0.0142647 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.014186 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0140034 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0139511 |
| NUF2 | NUF2, NDC80 kinetochore complex component | -0.0138142 |
| KIF14 | kinesin family member 14 | -0.0137757 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.013727 |
| IER3 | immediate early response 3 | -0.013616 |
| GNAS | GNAS complex locus | -0.0133735 |
| PXDN | peroxidasin | -0.013174 |
| CDCA2 | cell division cycle associated 2 | -0.0131595 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.0130562 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.013018 |
| CEP152 | centrosomal protein 152kDa | -0.012971 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0129385 |
| SRGN | serglycin | -0.0128686 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0127606 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.0127474 |
| PREPL | prolyl endopeptidase-like | -0.0126853 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0125613 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0125503 |
