| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the TAK-901_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.152251 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.112816 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0917914 |
| B2M | beta-2-microglobulin | 0.0743954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0708972 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0677932 |
| VEGFA | vascular endothelial growth factor A | 0.0649736 |
| KYNU | kynureninase | 0.0602137 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.059982 |
| MT2A | metallothionein 2A | 0.0597761 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0564741 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0527882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0520755 |
| ANXA2 | annexin A2 | 0.051799 |
| FTL | ferritin, light polypeptide | 0.0516767 |
| NDRG1 | N-myc downstream regulated 1 | 0.0512367 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0486825 |
| ARRDC3 | arrestin domain containing 3 | 0.0469578 |
| GOLGB1 | golgin B1 | 0.0446069 |
| SMAD3 | SMAD family member 3 | 0.0443255 |
| STC1 | stanniocalcin 1 | 0.0421504 |
| LOXL2 | lysyl oxidase-like 2 | 0.0414549 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0410843 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0400547 |
| CALR | calreticulin | 0.0378859 |
| PKM | pyruvate kinase, muscle | 0.0373101 |
| RPS6 | ribosomal protein S6 | 0.0363262 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0352256 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.035124 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0327952 |
| SETD5 | SET domain containing 5 | 0.0327588 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0318015 |
| INTS6 | integrator complex subunit 6 | 0.0317192 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0316692 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0315088 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0311964 |
| CANX | calnexin | 0.0311888 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0308957 |
| SON | SON DNA binding protein | 0.03023 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0299371 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0298924 |
| ADM | adrenomedullin | 0.0296226 |
| RAB1A | RAB1A, member RAS oncogene family | 0.029585 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0295336 |
| RPS3 | ribosomal protein S3 | 0.0295145 |
| RUNX1 | runt-related transcription factor 1 | 0.0293863 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0289148 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0288612 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0287329 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0276422 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0267227 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.026266 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0261892 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0261015 |
| AHNAK | AHNAK nucleoprotein | 0.0258639 |
| ENO1 | enolase 1, (alpha) | 0.0257944 |
| ASPH | aspartate beta-hydroxylase | 0.0256872 |
| ZNF292 | zinc finger protein 292 | 0.025553 |
| USP34 | ubiquitin specific peptidase 34 | 0.0249032 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0248799 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0248043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246937 |
| PTK2 | protein tyrosine kinase 2 | 0.0246046 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0244704 |
| MTDH | metadherin | 0.0242632 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0241901 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0235956 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0234561 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0234119 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0231579 |
| LAMB1 | laminin, beta 1 | 0.0226216 |
| MATR3 | matrin 3 | 0.0220205 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0215683 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0215057 |
| RPL5 | ribosomal protein L5 | 0.0213861 |
| YIPF5 | Yip1 domain family, member 5 | 0.0213184 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.021064 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.020919 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0209141 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0207179 |
| GOLGA4 | golgin A4 | 0.020586 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0205309 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0204467 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0203524 |
| ZNF638 | zinc finger protein 638 | 0.0203337 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.02028 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0202451 |
| FUS | FUS RNA binding protein | 0.0201659 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.020146 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0197147 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0196404 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0196321 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0195455 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0194661 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0193105 |
| CUL3 | cullin 3 | 0.0192325 |
| FAM13A | family with sequence similarity 13, member A | 0.019133 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0190062 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0189137 |
| VMP1 | vacuole membrane protein 1 | 0.0188971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0834844 |
| COL1A2 | collagen, type I, alpha 2 | -0.0689816 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0652372 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0630413 |
| LOX | lysyl oxidase | -0.0579938 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0515698 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0515475 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0495107 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0451986 |
| MT1X | metallothionein 1X | -0.0373527 |
| FN1 | fibronectin 1 | -0.0368309 |
| COL1A1 | collagen, type I, alpha 1 | -0.036453 |
| TMSB10 | thymosin beta 10 | -0.0361411 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0331298 |
| POTEF | POTE ankyrin domain family, member F | -0.0309111 |
| PRSS23 | protease, serine, 23 | -0.030747 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0272847 |
| CDH13 | cadherin 13 | -0.0271775 |
| PGK1 | phosphoglycerate kinase 1 | -0.0220979 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0217307 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0214914 |
| S100A6 | S100 calcium binding protein A6 | -0.0209825 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0200705 |
| HLA-B | major histocompatibility complex, class I, B | -0.0194961 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0192656 |
| IL6 | interleukin 6 | -0.0192161 |
| TNNC1 | troponin C type 1 (slow) | -0.0183932 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0173097 |
| ATP13A3 | ATPase type 13A3 | -0.0170823 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | -0.0161152 |
| MMP12 | matrix metallopeptidase 12 | -0.0154681 |
| DIAPH3 | diaphanous-related formin 3 | -0.0154498 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0154371 |
| GNAS | GNAS complex locus | -0.015145 |
| TPM1 | tropomyosin 1 (alpha) | -0.0151228 |
| EGR1 | early growth response 1 | -0.0150075 |
| TPM4 | tropomyosin 4 | -0.0147589 |
| CALU | calumenin | -0.0145709 |
| SEPTIN7 | septin 7 | -0.0143696 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0141789 |
| TUBB | tubulin, beta class I | -0.01401 |
| BSG | basigin (Ok blood group) | -0.013972 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0138992 |
| HLA-C | major histocompatibility complex, class I, C | -0.0138661 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0136815 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0136413 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0133988 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0132113 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0130873 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0128105 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0128005 |
| RTN4 | reticulon 4 | -0.0125487 |
| CD82 | CD82 molecule | -0.0123783 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0123597 |
| FBN1 | fibrillin 1 | -0.0123462 |
| SMIM44 | small integral membrane protein 44 | -0.012163 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0116946 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0115477 |
| MAP4 | microtubule-associated protein 4 | -0.0114972 |
| ANLN | anillin, actin binding protein | -0.01142 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0112965 |
| COL7A1 | collagen, type VII, alpha 1 | -0.011108 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0110381 |
| AAK1 | AP2 associated kinase 1 | -0.0109547 |
| CAPNS1 | calpain, small subunit 1 | -0.010946 |
| TUBA1B | tubulin, alpha 1b | -0.0108978 |
| STC2 | stanniocalcin 2 | -0.0108527 |
| INSIG1 | insulin induced gene 1 | -0.0108408 |
| IL1B | interleukin 1, beta | -0.0106993 |
| ACTG1 | actin gamma 1 | -0.0106791 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0105136 |
| TMEM165 | transmembrane protein 165 | -0.0104931 |
| PURA | purine-rich element binding protein A | -0.0104575 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.0104437 |
| FAM162A | family with sequence similarity 162, member A | -0.0102797 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0101917 |
| NRG1 | neuregulin 1 | -0.0101146 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.010104 |
| S100A10 | S100 calcium binding protein A10 | -0.0100342 |
| ZNF827 | zinc finger protein 827 | -0.00997749 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00994135 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.00993341 |
| CA9 | carbonic anhydrase IX | -0.00991915 |
| COL3A1 | collagen, type III, alpha 1 | -0.00970548 |
| BTG3 | BTG family, member 3 | -0.00963494 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00962139 |
| TMEM41B | transmembrane protein 41B | -0.00936101 |
| VCL | vinculin | -0.00919765 |
| AGRN | agrin | -0.00915024 |
| WASF2 | WAS protein family, member 2 | -0.00904781 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.00901326 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00890776 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.0088876 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00888221 |
| TAGLN2 | transgelin 2 | -0.00882454 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00881424 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.00876269 |
| CENPK | centromere protein K | -0.00873556 |
| RHOB | ras homolog family member B | -0.00869364 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0086605 |
