| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.128985 |
| FNDC3B | fibronectin type III domain containing 3B | 0.11584 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.102488 |
| CD44 | CD44 molecule (Indian blood group) | 0.096953 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0730377 |
| SMAD3 | SMAD family member 3 | 0.0723493 |
| LDHA | lactate dehydrogenase A | 0.069062 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0686782 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0661728 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0653253 |
| INTS6 | integrator complex subunit 6 | 0.0652872 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0616412 |
| SQSTM1 | sequestosome 1 | 0.060937 |
| PRKCA | protein kinase C, alpha | 0.0549235 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0540489 |
| HMGA2 | high mobility group AT-hook 2 | 0.0525127 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0522521 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0513967 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.049338 |
| ENO1 | enolase 1, (alpha) | 0.049329 |
| DST | dystonin | 0.0486734 |
| FMNL2 | formin-like 2 | 0.0477234 |
| HDAC9 | histone deacetylase 9 | 0.0459513 |
| ANGPTL4 | angiopoietin-like 4 | 0.0458941 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0457187 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0450113 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0444812 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0437137 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0423169 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0418385 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0410954 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0401456 |
| ASPH | aspartate beta-hydroxylase | 0.0387199 |
| VMP1 | vacuole membrane protein 1 | 0.0385651 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0383774 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0383086 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0382806 |
| CANX | calnexin | 0.0380168 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0370543 |
| PKM | pyruvate kinase, muscle | 0.0365244 |
| GOLGB1 | golgin B1 | 0.0363161 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0362293 |
| PTK2 | protein tyrosine kinase 2 | 0.0362071 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0361003 |
| PARD3 | par-3 family cell polarity regulator | 0.0354414 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0351069 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0349741 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0348219 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0344885 |
| FNIP1 | folliculin interacting protein 1 | 0.0344645 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0340296 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.033848 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0337566 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0336681 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0334667 |
| AHNAK | AHNAK nucleoprotein | 0.0331217 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0327717 |
| GPHN | gephyrin | 0.0325364 |
| ANO6 | anoctamin 6 | 0.032526 |
| ANXA2 | annexin A2 | 0.0324539 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0321723 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0320087 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0319005 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0318803 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0317203 |
| NAV3 | neuron navigator 3 | 0.0313332 |
| FLNB | filamin B, beta | 0.0302649 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0301514 |
| EGR1 | early growth response 1 | 0.0301061 |
| B2M | beta-2-microglobulin | 0.030106 |
| RBM39 | RNA binding motif protein 39 | 0.0301058 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0297613 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0296141 |
| AEBP2 | AE binding protein 2 | 0.029475 |
| RPS3 | ribosomal protein S3 | 0.0293841 |
| ZNF638 | zinc finger protein 638 | 0.0289456 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0285204 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0279976 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0278242 |
| TLE4 | transducin-like enhancer of split 4 | 0.027767 |
| SMYD3 | SET and MYND domain containing 3 | 0.0275498 |
| HPCAL1 | hippocalcin-like 1 | 0.0275176 |
| S100A10 | S100 calcium binding protein A10 | 0.0275005 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0274674 |
| ATM | ATM serine/threonine kinase | 0.0272979 |
| DIAPH1 | diaphanous-related formin 1 | 0.0272899 |
| SIK3 | SIK family kinase 3 | 0.0271141 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270588 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0270335 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0270245 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0269317 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0268269 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0262811 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0262499 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0260823 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0260798 |
| TPI1 | triosephosphate isomerase 1 | 0.0260771 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0259909 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0259869 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0258804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0493004 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0447362 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0419312 |
| TPX2 | TPX2, microtubule-associated | -0.0403112 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0400155 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390508 |
| TMEM123 | transmembrane protein 123 | -0.0357757 |
| SGO2 | shugoshin 2 | -0.0357568 |
| SNX14 | sorting nexin 14 | -0.0348873 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0348494 |
| CENPF | centromere protein F, 350/400kDa | -0.0340339 |
| BSG | basigin (Ok blood group) | -0.0339359 |
| NUP58 | nucleoporin 58 | -0.0336409 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0336154 |
| PTMA | prothymosin, alpha | -0.0315432 |
| INSIG1 | insulin induced gene 1 | -0.0295595 |
| DIAPH3 | diaphanous-related formin 3 | -0.029444 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0293911 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0288686 |
| SMC4 | structural maintenance of chromosomes 4 | -0.028815 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0284393 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0277331 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0275076 |
| RPL7 | ribosomal protein L7 | -0.0269938 |
| PRR11 | proline rich 11 | -0.0266212 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0266019 |
| ECT2 | epithelial cell transforming 2 | -0.0262927 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0258758 |
| CEP295 | centrosomal protein 295kDa | -0.0257783 |
| WDR45B | WD repeat domain 45B | -0.025571 |
| HELZ | helicase with zinc finger | -0.0255006 |
| LDHB | lactate dehydrogenase B | -0.0252316 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0249947 |
| SEPTIN7 | septin 7 | -0.0246812 |
| RPLP0 | ribosomal protein, large, P0 | -0.0241651 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.023809 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0233925 |
| HJURP | Holliday junction recognition protein | -0.0232338 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0228642 |
| PERP | PERP, TP53 apoptosis effector | -0.0223285 |
| PHF21A | PHD finger protein 21A | -0.0220223 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0219467 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0216338 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0216224 |
| USP3 | ubiquitin specific peptidase 3 | -0.0211216 |
| FANCI | Fanconi anemia, complementation group I | -0.0211037 |
| ANLN | anillin, actin binding protein | -0.0210706 |
| CENPC | centromere protein C | -0.020882 |
| KIF18B | kinesin family member 18B | -0.020646 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0206394 |
| TUBA1B | tubulin, alpha 1b | -0.0206061 |
| MKI67 | marker of proliferation Ki-67 | -0.0202029 |
| AURKA | aurora kinase A | -0.0201184 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0196961 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0196833 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0195916 |
| FAM76B | family with sequence similarity 76, member B | -0.0195822 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0194795 |
| PREPL | prolyl endopeptidase-like | -0.0194499 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0191725 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0191081 |
| HBP1 | HMG-box transcription factor 1 | -0.0190497 |
| NGLY1 | N-glycanase 1 | -0.0188973 |
| YAF2 | YY1 associated factor 2 | -0.018866 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0188397 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0187824 |
| RPS20 | ribosomal protein S20 | -0.0187679 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0187224 |
| PDS5B | PDS5 cohesin associated factor B | -0.0186695 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0184926 |
| CDK19 | cyclin-dependent kinase 19 | -0.0184373 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0183588 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0181917 |
| KIF4A | kinesin family member 4A | -0.0179967 |
| RTN4 | reticulon 4 | -0.0178745 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0178612 |
| PHF20 | PHD finger protein 20 | -0.0177035 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0174199 |
| CNTRL | centriolin | -0.0174113 |
| TTK | TTK protein kinase | -0.0172632 |
| PFN1 | profilin 1 | -0.0171964 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0171926 |
| SNX1 | sorting nexin 1 | -0.0171069 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0170475 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0170442 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0170099 |
| RAI1 | retinoic acid induced 1 | -0.0169989 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0169934 |
| CEP57L1 | centrosomal protein 57kDa-like 1 | -0.0168988 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0168667 |
| SERF2 | small EDRK-rich factor 2 | -0.0168122 |
| TOM1L1 | target of myb1 (chicken)-like 1 | -0.01672 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0166565 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0166008 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -0.0165735 |
| STMN1 | stathmin 1 | -0.0165683 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0165607 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0163753 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0163494 |
| RLIM | ring finger protein, LIM domain interacting | -0.0163288 |
