| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.19537 |
| EXT1 | exostosin glycosyltransferase 1 | 0.123221 |
| FNDC3B | fibronectin type III domain containing 3B | 0.120253 |
| PRRC2C | proline-rich coiled-coil 2C | 0.080877 |
| SMAD3 | SMAD family member 3 | 0.0792654 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0790278 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0753498 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0686505 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0657223 |
| VEGFA | vascular endothelial growth factor A | 0.0644897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0637719 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0635662 |
| PTK2 | protein tyrosine kinase 2 | 0.0610519 |
| AHR | aryl hydrocarbon receptor | 0.0607003 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0577199 |
| B2M | beta-2-microglobulin | 0.0553657 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0551404 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0526825 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0505803 |
| DST | dystonin | 0.0503569 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0491522 |
| RASAL2 | RAS protein activator like 2 | 0.048887 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0473993 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0470477 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0464735 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0462165 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0461549 |
| SEPTIN9 | septin 9 | 0.0458164 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0447296 |
| TXNIP | thioredoxin interacting protein | 0.0446718 |
| MT2A | metallothionein 2A | 0.0438362 |
| TXNRD1 | thioredoxin reductase 1 | 0.0438353 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0438334 |
| ASPH | aspartate beta-hydroxylase | 0.0433158 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0430697 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0428467 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0413062 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0412951 |
| RNF145 | ring finger protein 145 | 0.040771 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0403 |
| TPR | translocated promoter region, nuclear basket protein | 0.0402102 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0391277 |
| SMYD3 | SET and MYND domain containing 3 | 0.0388678 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0388373 |
| RPS6 | ribosomal protein S6 | 0.0380859 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.037598 |
| RPL26 | ribosomal protein L26 | 0.0373997 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0372401 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0371959 |
| RPS12 | ribosomal protein S12 | 0.0365464 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.036244 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0361197 |
| SVIL | supervillin | 0.0360393 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0348747 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0346917 |
| SIK3 | SIK family kinase 3 | 0.0345545 |
| RBM25 | RNA binding motif protein 25 | 0.0343736 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0341292 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0338642 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0336095 |
| RUNX1 | runt-related transcription factor 1 | 0.0333171 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0331087 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0328315 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0328041 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.032802 |
| ENAH | enabled homolog (Drosophila) | 0.0327559 |
| JMJD1C | jumonji domain containing 1C | 0.0326965 |
| FAT1 | FAT atypical cadherin 1 | 0.0323664 |
| CD44 | CD44 molecule (Indian blood group) | 0.0322093 |
| EREG | epiregulin | 0.0318746 |
| TPM3 | tropomyosin 3 | 0.0318684 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0318546 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.031817 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0312062 |
| ERBIN | erbb2 interacting protein | 0.0309348 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0307806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.030623 |
| CTBP2 | C-terminal binding protein 2 | 0.0305413 |
| GLIS3 | GLIS family zinc finger 3 | 0.030185 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0301748 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0301053 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300593 |
| PNN | pinin, desmosome associated protein | 0.0297806 |
| MYOF | myoferlin | 0.0297295 |
| ZNF292 | zinc finger protein 292 | 0.0295219 |
| YBX3 | Y box binding protein 3 | 0.02942 |
| RPS3 | ribosomal protein S3 | 0.0293871 |
| ATXN1 | ataxin 1 | 0.0292295 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0291179 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0290421 |
| MAP1B | microtubule-associated protein 1B | 0.0285459 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0283221 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0282393 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0280751 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0280083 |
| ZNF638 | zinc finger protein 638 | 0.0276449 |
| TGFB2 | transforming growth factor, beta 2 | 0.0276095 |
| FOXP1 | forkhead box P1 | 0.0272753 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0271883 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0268069 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.213378 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.182805 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.152976 |
| PTMA | prothymosin, alpha | -0.144317 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.129643 |
| NRG1 | neuregulin 1 | -0.106246 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0991471 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0989352 |
| S100A6 | S100 calcium binding protein A6 | -0.0924033 |
| ITGA1 | integrin, alpha 1 | -0.0801203 |
| TMSB10 | thymosin beta 10 | -0.0719137 |
| HMGA2 | high mobility group AT-hook 2 | -0.0607523 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.056497 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0561162 |
| TMSB4X | thymosin beta 4, X-linked | -0.0489287 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0489222 |
| SQSTM1 | sequestosome 1 | -0.0465468 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0459844 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0447841 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0446378 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0430477 |
| CANX | calnexin | -0.0383263 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0373441 |
| RAI14 | retinoic acid induced 14 | -0.0367777 |
| EGR1 | early growth response 1 | -0.0364809 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0330917 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0328087 |
| CADM1 | cell adhesion molecule 1 | -0.0326415 |
| LOX | lysyl oxidase | -0.0320099 |
| IER3 | immediate early response 3 | -0.0293054 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0287135 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0286668 |
| KLF10 | Kruppel-like factor 10 | -0.0283974 |
| FTL | ferritin, light polypeptide | -0.0278612 |
| SYT1 | synaptotagmin I | -0.0277798 |
| TMEM263 | transmembrane protein 263 | -0.0271141 |
| TMEM165 | transmembrane protein 165 | -0.0270343 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0266139 |
| CTSD | cathepsin D | -0.0260611 |
| HLA-A | major histocompatibility complex, class I, A | -0.0259881 |
| H1-0 | H1.0 linker histone | -0.0256705 |
| PLIN2 | perilipin 2 | -0.0256509 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0244343 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0241288 |
| HLA-B | major histocompatibility complex, class I, B | -0.0239992 |
| ACTG1 | actin gamma 1 | -0.0239898 |
| TENM4 | teneurin transmembrane protein 4 | -0.0221563 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.020265 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0194295 |
| TGFA | transforming growth factor, alpha | -0.0187464 |
| GNAS | GNAS complex locus | -0.0185352 |
| MKI67 | marker of proliferation Ki-67 | -0.0183602 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0181831 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0181806 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.018159 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0178484 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0177964 |
| HLA-E | major histocompatibility complex, class I, E | -0.0177577 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0175957 |
| HDLBP | high density lipoprotein binding protein | -0.0175204 |
| CENPF | centromere protein F, 350/400kDa | -0.0171104 |
| TUBA1B | tubulin, alpha 1b | -0.0170296 |
| HMGA1 | high mobility group AT-hook 1 | -0.0167758 |
| ETV1 | ets variant 1 | -0.0164479 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0164051 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.016357 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.016174 |
| RPS24 | ribosomal protein S24 | -0.0158978 |
| RPS21 | ribosomal protein S21 | -0.0156725 |
| HMGB1 | high mobility group box 1 | -0.0153115 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0152395 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0148665 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0146541 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0146132 |
| INSIG1 | insulin induced gene 1 | -0.014144 |
| CP | ceruloplasmin (ferroxidase) | -0.0138815 |
| MMP13 | matrix metallopeptidase 13 | -0.0138278 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0137901 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0135402 |
| AGR2 | anterior gradient 2 | -0.0132229 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | -0.0131598 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0129838 |
| HMGB3 | high mobility group box 3 | -0.0129262 |
| FAM20C | family with sequence similarity 20, member C | -0.0128944 |
| DUSP6 | dual specificity phosphatase 6 | -0.0128771 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0128172 |
| FOSL1 | FOS-like antigen 1 | -0.012799 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0126597 |
| TPM4 | tropomyosin 4 | -0.0126552 |
| S100A9 | S100 calcium binding protein A9 | -0.0126215 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.012281 |
| KRT19 | keratin 19, type I | -0.0122772 |
| KRT81 | keratin 81, type II | -0.0122199 |
| ARF1 | ADP-ribosylation factor 1 | -0.0119444 |
| IGF2 | insulin-like growth factor 2 | -0.0118365 |
| NRN1 | neuritin 1 | -0.0117253 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0116649 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0116594 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0116563 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0115922 |
