| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | TAK-901 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the TAK-901_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.200859 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.130323 |
| SYT1 | synaptotagmin I | 0.126455 |
| RPS6 | ribosomal protein S6 | 0.0955127 |
| TNS3 | tensin 3 | 0.0901362 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.088192 |
| RPS12 | ribosomal protein S12 | 0.084697 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0814669 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.080236 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0800494 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0762056 |
| LMO7 | LIM domain 7 | 0.07522 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0717778 |
| RPS3 | ribosomal protein S3 | 0.0711274 |
| EZR | ezrin | 0.0707842 |
| INTS6 | integrator complex subunit 6 | 0.0662335 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0646481 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0644782 |
| SVIL | supervillin | 0.0643275 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0632223 |
| RPL26 | ribosomal protein L26 | 0.0616122 |
| YAP1 | Yes-associated protein 1 | 0.0597437 |
| RPL37A | ribosomal protein L37a | 0.058165 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0574733 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0572266 |
| DST | dystonin | 0.0562218 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0554063 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0538645 |
| MED13 | mediator complex subunit 13 | 0.0534655 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0523773 |
| SETD5 | SET domain containing 5 | 0.0519524 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0467267 |
| ZNF638 | zinc finger protein 638 | 0.0460255 |
| EFNB2 | ephrin-B2 | 0.045946 |
| YBX1 | Y box binding protein 1 | 0.0450382 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0443675 |
| SON | SON DNA binding protein | 0.0443052 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0441135 |
| SMAD3 | SMAD family member 3 | 0.0439491 |
| JMJD1C | jumonji domain containing 1C | 0.043462 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0431951 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0430583 |
| DSPP | dentin sialophosphoprotein | 0.0419229 |
| RPS17 | ribosomal protein S17 | 0.0418431 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0418019 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.041466 |
| BPTF | bromodomain PHD finger transcription factor | 0.0413017 |
| ANXA2 | annexin A2 | 0.0401328 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0397465 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0394867 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.038503 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0383039 |
| GOLGB1 | golgin B1 | 0.0382473 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0380428 |
| ASPH | aspartate beta-hydroxylase | 0.0375598 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0373164 |
| RPL7 | ribosomal protein L7 | 0.0366779 |
| PNN | pinin, desmosome associated protein | 0.036361 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0362077 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0361785 |
| ATXN1 | ataxin 1 | 0.0360927 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0360325 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0359279 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0357219 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0356934 |
| BRD2 | bromodomain containing 2 | 0.0350279 |
| VMP1 | vacuole membrane protein 1 | 0.034868 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.034842 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0345289 |
| ETNK1 | ethanolamine kinase 1 | 0.0344886 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0342259 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0341367 |
| USP47 | ubiquitin specific peptidase 47 | 0.0341141 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0339976 |
| KLF12 | Kruppel-like factor 12 | 0.0339767 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0331057 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330868 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0330156 |
| FAT1 | FAT atypical cadherin 1 | 0.03281 |
| MSN | moesin | 0.0326384 |
| RCOR1 | REST corepressor 1 | 0.0326161 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0323936 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.032371 |
| PRPF8 | pre-mRNA processing factor 8 | 0.032278 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.031903 |
| MT2A | metallothionein 2A | 0.0318493 |
| RPS23 | ribosomal protein S23 | 0.0311852 |
| RUNX1 | runt-related transcription factor 1 | 0.0311284 |
| TOX3 | TOX high mobility group box family member 3 | 0.0304806 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0304736 |
| PKM | pyruvate kinase, muscle | 0.0303884 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0302947 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0301783 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0300881 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0300768 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0300192 |
| FNIP1 | folliculin interacting protein 1 | 0.0299876 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0299305 |
| RACK1 | receptor for activated C kinase 1 | 0.0299236 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0299162 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.145499 |
| CCND1 | cyclin D1 | -0.0778562 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0754529 |
| KRT18 | keratin 18, type I | -0.07327 |
| TMSB10 | thymosin beta 10 | -0.0709719 |
| KRT8 | keratin 8, type II | -0.0660556 |
| ACTG1 | actin gamma 1 | -0.0608113 |
| RPS24 | ribosomal protein S24 | -0.06043 |
| ANLN | anillin, actin binding protein | -0.0592713 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0591598 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532863 |
| MKI67 | marker of proliferation Ki-67 | -0.0524164 |
| PGK1 | phosphoglycerate kinase 1 | -0.0495891 |
| HMGB1 | high mobility group box 1 | -0.0491974 |
| H1-0 | H1.0 linker histone | -0.0471907 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0456968 |
| EGR1 | early growth response 1 | -0.0455831 |
| AHNAK | AHNAK nucleoprotein | -0.0430603 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0420839 |
| KPNB1 | karyopherin (importin) beta 1 | -0.041279 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0410779 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0396002 |
| RPL34 | ribosomal protein L34 | -0.0385 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0382896 |
| RBP1 | retinol binding protein 1, cellular | -0.0381429 |
| TMSB4X | thymosin beta 4, X-linked | -0.0378263 |
| RPL35A | ribosomal protein L35a | -0.0376462 |
| HMGA1 | high mobility group AT-hook 1 | -0.0364677 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0364339 |
| S100A6 | S100 calcium binding protein A6 | -0.0345926 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0344809 |
| TUBA1B | tubulin, alpha 1b | -0.0341444 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0328358 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320679 |
| TUBB | tubulin, beta class I | -0.0319125 |
| RPS21 | ribosomal protein S21 | -0.0318942 |
| DIAPH3 | diaphanous-related formin 3 | -0.0305716 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.030483 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0303279 |
| RPLP0 | ribosomal protein, large, P0 | -0.0300218 |
| HMGB2 | high mobility group box 2 | -0.0297737 |
| ABLIM1 | actin binding LIM protein 1 | -0.0294694 |
| KLF10 | Kruppel-like factor 10 | -0.029242 |
| TMEM123 | transmembrane protein 123 | -0.0291236 |
| ARRDC3 | arrestin domain containing 3 | -0.028411 |
| TPX2 | TPX2, microtubule-associated | -0.027327 |
| IER3 | immediate early response 3 | -0.0272301 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0271788 |
| CENPF | centromere protein F, 350/400kDa | -0.0270871 |
| PERP | PERP, TP53 apoptosis effector | -0.0265484 |
| RAD51B | RAD51 paralog B | -0.0261304 |
| S100A4 | S100 calcium binding protein A4 | -0.0258128 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0251954 |
| EPCAM | epithelial cell adhesion molecule | -0.0248436 |
| TPM4 | tropomyosin 4 | -0.0244325 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0233288 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0229399 |
| RPL27A | ribosomal protein L27a | -0.0228474 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0227511 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0226579 |
| CBX3 | chromobox homolog 3 | -0.0226187 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0224176 |
| GNAS | GNAS complex locus | -0.0223553 |
| DEK | DEK proto-oncogene | -0.0221189 |
| TUBA1C | tubulin, alpha 1c | -0.0219414 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0217299 |
| MT1X | metallothionein 1X | -0.0215746 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0215707 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0214984 |
| DUSP6 | dual specificity phosphatase 6 | -0.0213098 |
| FHIT | fragile histidine triad | -0.0213036 |
| KHSRP | KH-type splicing regulatory protein | -0.0212837 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0212417 |
| SDC4 | syndecan 4 | -0.021154 |
| RPL6 | ribosomal protein L6 | -0.0207722 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0205797 |
| FLNB | filamin B, beta | -0.0204187 |
| RRM2 | ribonucleotide reductase M2 | -0.0204175 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0204015 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0203415 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.019831 |
| MYO1D | myosin ID | -0.0195895 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0192096 |
| RPL4 | ribosomal protein L4 | -0.0191105 |
| FOSL1 | FOS-like antigen 1 | -0.0190938 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0190181 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0187983 |
| APCDD1 | adenomatosis polyposis coli down-regulated 1 | -0.0185282 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.018177 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0181578 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0181371 |
| XPO7 | exportin 7 | -0.018034 |
| OXR1 | oxidation resistance 1 | -0.0180022 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0179365 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0179249 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.017832 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0175946 |
| ACTN4 | actinin, alpha 4 | -0.0172249 |
| ITGB4 | integrin, beta 4 | -0.0171765 |
| RPLP1 | ribosomal protein, large, P1 | -0.0170439 |
