TAK1-dependent IKK and NF-kappa-B activation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-445989
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Genes

44 proteins participating in the TAK1-dependent IKK and NF-kappa-B activation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
ALPK1 alpha-kinase 1
APP amyloid beta (A4) precursor protein
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
HMGB1 high mobility group box 1
IKBIP IKBKB interacting protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
LRRC14 leucine rich repeat containing 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
N4BP1 NEDD4 binding protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK2 receptor-interacting serine-threonine kinase 2
RPS27A ribosomal protein S27a
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TIFA TRAF-interacting protein with forkhead-associated domain
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP18 ubiquitin specific peptidase 18