| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | TRAF family member-associated NFKB activator|The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] (NCBI Entrez Gene Database, 10010) |
| External Link | https://ncbi.nlm.nih.gov/gene/10010 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the TANK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 0.0170305 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0153442 |
| GNAS | GNAS complex locus | 0.0117734 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0117717 |
| CRYAB | crystallin, alpha B | 0.0116959 |
| CTSZ | cathepsin Z | 0.0114646 |
| KRT19 | keratin 19, type I | 0.0110916 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0105775 |
| LAMB1 | laminin, beta 1 | 0.0105062 |
| AK1 | adenylate kinase 1 | 0.00987186 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00973817 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00965302 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00950805 |
| ACKR3 | atypical chemokine receptor 3 | 0.00947699 |
| FHL1 | four and a half LIM domains 1 | 0.00944809 |
| RBPMS | RNA binding protein with multiple splicing | 0.00942164 |
| MAP7 | microtubule-associated protein 7 | 0.00938891 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0092348 |
| PERP | PERP, TP53 apoptosis effector | 0.00921913 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00920438 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00920139 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.0091922 |
| IL6 | interleukin 6 | 0.00914818 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00913154 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00908196 |
| STK39 | serine threonine kinase 39 | 0.00903183 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00900573 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00889088 |
| ECM1 | extracellular matrix protein 1 | 0.00883882 |
| MYO6 | myosin VI | 0.00876918 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00870598 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0086756 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00864361 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00862778 |
| PMP22 | peripheral myelin protein 22 | 0.00857932 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00856984 |
| MYOF | myoferlin | 0.00856611 |
| MFAP5 | microfibrillar associated protein 5 | 0.00846657 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00845448 |
| KRT18 | keratin 18, type I | 0.0083858 |
| MVP | major vault protein | 0.00834567 |
| PLK2 | polo-like kinase 2 | 0.00832663 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00826295 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00825346 |
| PITX1 | paired-like homeodomain 1 | 0.00822559 |
| CEL | carboxyl ester lipase | 0.00817514 |
| LUM | lumican | 0.00804404 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00799975 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00798689 |
| THBS2 | thrombospondin 2 | 0.00795792 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00780983 |
| ASPH | aspartate beta-hydroxylase | 0.00778081 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00772358 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00768853 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00768253 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00767126 |
| SIK1 | salt-inducible kinase 1 | 0.00765457 |
| PROM1 | prominin 1 | 0.00765064 |
| CHEK2 | checkpoint kinase 2 | 0.00762752 |
| JUNB | jun B proto-oncogene | 0.00759801 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00755465 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00755386 |
| MGLL | monoglyceride lipase | 0.00752749 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00748672 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00748274 |
| ATP9A | ATPase, class II, type 9A | 0.00745841 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00744623 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00743303 |
| PLIN1 | perilipin 1 | 0.00738782 |
| CCN2 | cellular communication network factor 2 | 0.00738 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00737129 |
| DST | dystonin | 0.00735932 |
| FN1 | fibronectin 1 | 0.00734919 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00734207 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00733512 |
| CCNA2 | cyclin A2 | 0.00731064 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00730151 |
| AMOTL2 | angiomotin like 2 | 0.00729454 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00726063 |
| SPATA20 | spermatogenesis associated 20 | 0.00723377 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00721672 |
| CUX1 | cut-like homeobox 1 | 0.0071274 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00711916 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00709106 |
| GPC3 | glypican 3 | 0.00707083 |
| HMOX1 | heme oxygenase 1 | 0.00706387 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00705151 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 0.00703705 |
| S100A10 | S100 calcium binding protein A10 | 0.00703516 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.00702478 |
| MIR22HG | MIR22 host gene | 0.00701668 |
| JMJD6 | jumonji domain containing 6 | 0.00701423 |
| C3 | complement component 3 | 0.00699554 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00696025 |
| POSTN | periostin, osteoblast specific factor | 0.00694831 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00692969 |
| DCN | decorin | 0.00692907 |
| THBS4 | thrombospondin 4 | 0.0069209 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0069074 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00690699 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00690421 |
| FADS3 | fatty acid desaturase 3 | 0.0068554 |
| SPRR3 | small proline-rich protein 3 | 0.00680867 |
| TNNC1 | troponin C type 1 (slow) | 0.00671281 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00671028 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00670952 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00668941 |
| ATF3 | activating transcription factor 3 | 0.00668393 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00664511 |
| KRT7 | keratin 7, type II | 0.00661758 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00661649 |
| LPIN1 | lipin 1 | 0.0066144 |
| LAMA2 | laminin, alpha 2 | 0.00660242 |
| G0S2 | G0/G1 switch 2 | 0.00655734 |
| TPM2 | tropomyosin 2 (beta) | 0.00652925 |
| COQ8A | coenzyme Q8A | 0.00652584 |
| RCAN2 | regulator of calcineurin 2 | 0.00650737 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 0.00649992 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00647102 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0064641 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.00645229 |
| KLF2 | Kruppel-like factor 2 | 0.0064434 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00643945 |
| GPX3 | glutathione peroxidase 3 | 0.00642759 |
| PLPP2 | phospholipid phosphatase 2 | 0.0064201 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00638339 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00637013 |
| EFNA1 | ephrin-A1 | 0.00635843 |
| TPD52L1 | tumor protein D52-like 1 | 0.00634985 |
| PROCR | protein C receptor, endothelial | 0.00634795 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00631726 |
| S100A11 | S100 calcium binding protein A11 | 0.0063118 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00630264 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00629244 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00628821 |
| DUSP5 | dual specificity phosphatase 5 | 0.00628664 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00627798 |
| MITF | microphthalmia-associated transcription factor | 0.00626568 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00625044 |
| PSCA | prostate stem cell antigen | 0.00624808 |
| JMJD1C | jumonji domain containing 1C | 0.00624113 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0062094 |
| EGR1 | early growth response 1 | 0.00619942 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00615356 |
| MGP | matrix Gla protein | 0.00612985 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00608273 |
| CNTN1 | contactin 1 | 0.00608079 |
| DUSP1 | dual specificity phosphatase 1 | 0.00603477 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00603439 |
| FAM50A | family with sequence similarity 50, member A | 0.0060305 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00600151 |
| TPCN1 | two pore segment channel 1 | 0.00598526 |
| PRSS23 | protease, serine, 23 | 0.00598375 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00597819 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00597014 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00596507 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.00594376 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00594169 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00591272 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00589918 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00588251 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00585831 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00585249 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0058495 |
| KLF9 | Kruppel-like factor 9 | 0.00581078 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00580776 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.0058052 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00579774 |
| CTSA | cathepsin A | 0.00579104 |
| ATP13A3 | ATPase type 13A3 | 0.00577817 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0057748 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00577415 |
| ANGPT1 | angiopoietin 1 | 0.00576696 |
| BTG2 | BTG family, member 2 | 0.00576499 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00573253 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.00572855 |
| ADM | adrenomedullin | 0.00572585 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00572427 |
| BAG2 | BCL2-associated athanogene 2 | 0.00571719 |
| TNNC2 | troponin C type 2 (fast) | 0.00571301 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00570929 |
| ADCY9 | adenylate cyclase 9 | 0.00570719 |
| SVIL | supervillin | 0.0056837 |
| FILIP1L | filamin A interacting protein 1-like | 0.00567256 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.00565462 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00564292 |
| ACTB | actin, beta | 0.00562946 |
| C1S | complement component 1, s subcomponent | 0.00562447 |
| FHL2 | four and a half LIM domains 2 | 0.00562328 |
| KLHL41 | kelch-like family member 41 | 0.00561771 |
| PLS3 | plastin 3 | 0.00559504 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00559448 |
| DSP | desmoplakin | 0.00558618 |
| FGF7 | fibroblast growth factor 7 | 0.00558527 |
| SMAD7 | SMAD family member 7 | 0.00557632 |
| ENAH | enabled homolog (Drosophila) | 0.00555686 |
| PEG10 | paternally expressed 10 | 0.00554989 |
| BMP2 | bone morphogenetic protein 2 | 0.00553663 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00552797 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00552352 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00547315 |
| CDC34 | cell division cycle 34 | 0.00547244 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00547079 |
| IER3 | immediate early response 3 | 0.0054533 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.00544041 |
| SDC2 | syndecan 2 | 0.00542989 |
| ZNF91 | zinc finger protein 91 | 0.00541351 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00539125 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00538745 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00537648 |
| CIDEC | cell death-inducing DFFA-like effector c | 0.00536654 |
| PCBP4 | poly(rC) binding protein 4 | 0.00536502 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00536441 |
| ASS1 | argininosuccinate synthase 1 | 0.00534907 |
| RUNX1 | runt-related transcription factor 1 | 0.00534687 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00534106 |
| TUFT1 | tuftelin 1 | 0.00531196 |
| RTN2 | reticulon 2 | 0.00530311 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00530144 |
| SQSTM1 | sequestosome 1 | 0.00525862 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00525743 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.00525701 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00525246 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.005224 |
| IGF2R | insulin-like growth factor 2 receptor | 0.00522299 |
| STK26 | serine/threonine protein kinase 26 | 0.00522003 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.00520833 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0052042 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.00519881 |
| DUSP2 | dual specificity phosphatase 2 | 0.0051965 |
| CDV3 | CDV3 homolog (mouse) | 0.00519266 |
| GOLGA8A | golgin A8 family, member A | 0.00518695 |
| MXRA5 | matrix-remodelling associated 5 | 0.00518391 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00518375 |
| PXDC1 | PX domain containing 1 | 0.00518011 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.00517922 |
| CKM | creatine kinase, muscle | 0.00517735 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.00517046 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00516509 |
| TENM3 | teneurin transmembrane protein 3 | 0.00513843 |
| FBLN1 | fibulin 1 | 0.00513333 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00513274 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00512699 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00510768 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00510702 |
| ACTN2 | actinin, alpha 2 | 0.00508753 |
| SIX1 | SIX homeobox 1 | 0.00508409 |
| AHR | aryl hydrocarbon receptor | 0.00505515 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00505151 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00504756 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PUF60 | poly-U binding splicing factor 60KDa | -0.0130123 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0128972 |
| ARG1 | arginase 1 | -0.0126721 |
| CLC | Charcot-Leyden crystal galectin | -0.0122914 |
| NTS | neurotensin | -0.0113367 |
| CA2 | carbonic anhydrase II | -0.0113112 |
| HAL | histidine ammonia-lyase | -0.0111135 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0109924 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0104198 |
| KRT1 | keratin 1, type II | -0.00999122 |
| LOR | loricrin | -0.00980074 |
| HBB | hemoglobin, beta | -0.00975751 |
| WT1 | Wilms tumor 1 | -0.00936713 |
| AQP9 | aquaporin 9 | -0.00929755 |
| KLK8 | kallikrein-related peptidase 8 | -0.00925639 |
| TYRP1 | tyrosinase-related protein 1 | -0.00924186 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00914394 |
| GPM6B | glycoprotein M6B | -0.0088131 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00870325 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00865018 |
| DSC1 | desmocollin 1 | -0.00862659 |
| FCGBP | Fc fragment of IgG binding protein | -0.00859726 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00859493 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.0085171 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00847538 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00842193 |
| NELL2 | NEL-like 2 (chicken) | -0.00837849 |
| THY1 | Thy-1 cell surface antigen | -0.00836472 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00833112 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00824896 |
| KRT2 | keratin 2, type II | -0.00812837 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00801408 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00792275 |
| NSG1 | neuron specific gene family member 1 | -0.00787751 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00786482 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00784642 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00784096 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00783469 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00781444 |
| KLK7 | kallikrein-related peptidase 7 | -0.00768868 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00767144 |
| FABP1 | fatty acid binding protein 1, liver | -0.00765504 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00762436 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00749095 |
| DNASE1L3 | deoxyribonuclease I-like 3 | -0.00748368 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00747415 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0074686 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00745675 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00744709 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00741605 |
| RRM2 | ribonucleotide reductase M2 | -0.00738743 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00735612 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00734265 |
| CD48 | CD48 molecule | -0.00733664 |
| FRZB | frizzled-related protein | -0.00732332 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00731705 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00725104 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00723761 |
| GPM6A | glycoprotein M6A | -0.00718451 |
| C7 | complement component 7 | -0.00715088 |
| LY75 | lymphocyte antigen 75 | -0.00695131 |
| OLFM4 | olfactomedin 4 | -0.00684117 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.006799 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00676951 |
| SORD | sorbitol dehydrogenase | -0.0067678 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00672997 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00672616 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00672 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00671686 |
| CLCA1 | chloride channel accessory 1 | -0.00670349 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00666847 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00657894 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00653059 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00651983 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00646405 |
| FABP7 | fatty acid binding protein 7, brain | -0.00644739 |
| DSG1 | desmoglein 1 | -0.00642978 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00642526 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00640662 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00635057 |
| CPOX | coproporphyrinogen oxidase | -0.00632313 |
| CCND2 | cyclin D2 | -0.00631549 |
| KYAT3 | kynurenine aminotransferase 3 | -0.00631407 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0062993 |
| IFI44L | interferon-induced protein 44-like | -0.00629042 |
| CCNF | cyclin F | -0.00626792 |
| FBXO5 | F-box protein 5 | -0.00623625 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00622896 |
| MPO | myeloperoxidase | -0.0062148 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00618508 |
| RAB38 | RAB38, member RAS oncogene family | -0.00617644 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00617536 |
| SRGN | serglycin | -0.0061707 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00615579 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00610275 |
| S100P | S100 calcium binding protein P | -0.00610182 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.0060587 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00605369 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00603883 |
| RUNX3 | runt-related transcription factor 3 | -0.00601088 |
| CYBRD1 | cytochrome b reductase 1 | -0.006006 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00599204 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00598519 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00597871 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00596724 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00593395 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00588532 |
| CST7 | cystatin F (leukocystatin) | -0.00587171 |
| ACP3 | acid phosphatase 3 | -0.00586638 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00585757 |
| LCE2B | late cornified envelope 2B | -0.00584879 |
| HBD | hemoglobin, delta | -0.00583301 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00577974 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00576272 |
| CDSN | corneodesmosin | -0.0057579 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00575216 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.0057473 |
| OIP5 | Opa interacting protein 5 | -0.00572991 |
| GLB1L2 | galactosidase, beta 1-like 2 | -0.00572889 |
| SELL | selectin L | -0.00572498 |
| TADA2A | transcriptional adaptor 2A | -0.00571482 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00571252 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00570874 |
| GRAMD1C | GRAM domain containing 1C | -0.00570551 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.005691 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00568017 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00564621 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00563963 |
| EPHA4 | EPH receptor A4 | -0.00562101 |
| CCNE2 | cyclin E2 | -0.00559984 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00558916 |
| HEPH | hephaestin | -0.00557378 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00556479 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00555964 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00554537 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00554079 |
| MSLN | mesothelin | -0.00553975 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00553882 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00553724 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00552794 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00552078 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00549945 |
| AGA | aspartylglucosaminidase | -0.00549021 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00547914 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00545439 |
| CENPU | centromere protein U | -0.0054535 |
| BCHE | butyrylcholinesterase | -0.00545279 |
| CALML5 | calmodulin-like 5 | -0.00544937 |
| MGAM | maltase-glucoamylase | -0.00544594 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | -0.00543923 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0054122 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.00540924 |
| LST1 | leukocyte specific transcript 1 | -0.00539988 |
| BRCA1 | breast cancer 1, early onset | -0.00538945 |
| SERINC5 | serine incorporator 5 | -0.00538267 |
| ZNF274 | zinc finger protein 274 | -0.0053815 |
| PCP4 | Purkinje cell protein 4 | -0.00537481 |
| ANXA6 | annexin A6 | -0.0053741 |
| ZNF226 | zinc finger protein 226 | -0.00535651 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00535461 |
| KLK5 | kallikrein-related peptidase 5 | -0.0053528 |
| MMP12 | matrix metallopeptidase 12 | -0.00535263 |
| RBBP8 | retinoblastoma binding protein 8 | -0.00534893 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.00534036 |
| CDC7 | cell division cycle 7 | -0.0053309 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.00533009 |
| POMZP3 | POM121 and ZP3 fusion | -0.00532908 |
| DHFR | dihydrofolate reductase | -0.00531296 |
| TMEM254 | transmembrane protein 254 | -0.00530044 |
| ANOS1 | anosmin 1 | -0.00528182 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -0.00526549 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00525991 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00525389 |
| KLK6 | kallikrein-related peptidase 6 | -0.00524978 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00524889 |
| CBR3 | carbonyl reductase 3 | -0.00524836 |
| IL2RG | interleukin 2 receptor, gamma | -0.0052409 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0052225 |
| C8ORF33 | chromosome 8 open reading frame 33 | -0.0052112 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00520259 |
| CD44 | CD44 molecule (Indian blood group) | -0.00519867 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00519262 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00518642 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00517513 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -0.00516281 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00513437 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00513175 |
| ELANE | elastase, neutrophil expressed | -0.00513023 |
| CD300A | CD300a molecule | -0.00511872 |
| SIRT3 | sirtuin 3 | -0.00510532 |
| LTF | lactotransferrin | -0.0050986 |
| TRMT5 | tRNA methyltransferase 5 | -0.00508529 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00507875 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00507076 |
| CYTL1 | cytokine-like 1 | -0.00506098 |
| ORC1 | origin recognition complex, subunit 1 | -0.00505445 |
| RAPSN | receptor-associated protein of the synapse | -0.00504693 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00504085 |
| EDNRB | endothelin receptor type B | -0.00503525 |
| FPGT | fucose-1-phosphate guanylyltransferase | -0.00503077 |
| SNX11 | sorting nexin 11 | -0.00503005 |
| FOXG1 | forkhead box G1 | -0.00502137 |
| HELLS | helicase, lymphoid-specific | -0.00501377 |
| PMEL | premelanosome protein | -0.00501059 |
| PRKCB | protein kinase C, beta | -0.00500054 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00499584 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 | -0.00499002 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00498705 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00498322 |
| NPTX2 | neuronal pentraxin II | -0.00496651 |
| CCNB1 | cyclin B1 | -0.00496087 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00495419 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | -0.00495315 |
| PRTN3 | proteinase 3 | -0.00494206 |
| TFR2 | transferrin receptor 2 | -0.00493794 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.0049221 |
| NEK2 | NIMA-related kinase 2 | -0.00491384 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00490421 |
| FOXM1 | forkhead box M1 | -0.00490149 |
| COPS4 | COP9 signalosome subunit 4 | -0.00490144 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00489356 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00488844 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | -0.00488671 |
| CRIP2 | cysteine-rich protein 2 | -0.00487327 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00487131 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0048412 |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 | -0.0048384 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | -0.00482616 |
| S100A12 | S100 calcium binding protein A12 | -0.00482355 |
| GANAB | glucosidase, alpha; neutral AB | -0.00481041 |
| LY6H | lymphocyte antigen 6 complex, locus H | -0.00480304 |
| ACTN1 | actinin, alpha 1 | -0.00479736 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00479407 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00478656 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | -0.00478372 |
| TRIM14 | tripartite motif containing 14 | -0.00478096 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00477995 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00477742 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00477657 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0047752 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00477435 |
| CD209 | CD209 molecule | -0.00477394 |
| MYO1C | myosin IC | -0.00477266 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00476881 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00476112 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00472777 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.0047268 |
| CLEC4A | C-type lectin domain family 4, member A | -0.00472011 |
