| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/TBK1.DN.48HRS_UP |
| Similar Terms | |
| Downloads & Tools |
100 genes differentially expressed following the TBK1.DN.48HRS gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| APOE | apolipoprotein E |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARL4C | ADP-ribosylation factor-like 4C |
| BAMBI | BMP and activin membrane-bound inhibitor |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CDK4 | cyclin-dependent kinase 4 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHEK2 | checkpoint kinase 2 |
| CHMP6 | charged multivesicular body protein 6 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DUSP3 | dual specificity phosphatase 3 |
| ECD | ecdysoneless homolog (Drosophila) |
| EDN1 | endothelin 1 |
| FCHO1 | FCH domain only 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| KIAA0907 | KIAA0907 |
| LBR | lamin B receptor |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 |
| MLEC | malectin |
| MTFR1 | mitochondrial fission regulator 1 |
| MYCBP | MYC binding protein |
| MYLK | myosin light chain kinase |
| OXSR1 | oxidative stress responsive 1 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTK2 | protein tyrosine kinase 2 |
| RBM15B | RNA binding motif protein 15B |
| RNMT | RNA (guanine-7-) methyltransferase |
| SCP2 | sterol carrier protein 2 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| TEX10 | testis expressed 10 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TP53BP1 | tumor protein p53 binding protein 1 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| UBQLN2 | ubiquilin 2 |
| UGDH | UDP-glucose 6-dehydrogenase |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| Symbol | Name |
|---|---|
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 |
| AKAP8 | A kinase (PRKA) anchor protein 8 |
| ANKRD10 | ankyrin repeat domain 10 |
| ATG3 | autophagy related 3 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BCL2 | B-cell CLL/lymphoma 2 |
| BIRC2 | baculoviral IAP repeat containing 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| CDK1 | cyclin-dependent kinase 1 |
| COASY | CoA synthase |
| COL4A1 | collagen, type IV, alpha 1 |
| CPNE3 | copine III |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DCK | deoxycytidine kinase |
| DLD | dihydrolipoamide dehydrogenase |
| DUSP22 | dual specificity phosphatase 22 |
| DUSP4 | dual specificity phosphatase 4 |
| EGF | epidermal growth factor |
| GALE | UDP-galactose-4-epimerase |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GTF2A2 | general transcription factor IIA, 2, 12kDa |
| H2AFV | H2A histone family, member V |
| HSPA1A | heat shock 70kDa protein 1A |
| IER3 | immediate early response 3 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| ITGB1BP1 | integrin beta 1 binding protein 1 |
| KIAA0100 | KIAA0100 |
| MAPK9 | mitogen-activated protein kinase 9 |
| MSRA | methionine sulfoxide reductase A |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDHX | pyruvate dehydrogenase complex, component X |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PPOX | protoporphyrinogen oxidase |
| PRKCQ | protein kinase C, theta |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| RAD51C | RAD51 paralog C |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STX1A | syntaxin 1A (brain) |
| TERF2IP | telomeric repeat binding factor 2, interacting protein |
| TOR1A | torsin family 1, member A (torsin A) |
| TRIB3 | tribbles pseudokinase 3 |
| UFM1 | ubiquitin-fold modifier 1 |
| XBP1 | X-box binding protein 1 |
