TBK1_knockdown_53_GSE17643 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE17643
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Genes

600 genes differentially expressed following the TBK1_knockdown_53_GSE17643 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
ERBB3 erb-b2 receptor tyrosine kinase 3 4.41998
EPHB2 EPH receptor B2 4.10723
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 3.44448
MEAF6 MYST/Esa1-associated factor 6 3.44053
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 3.40663
CKAP4 cytoskeleton-associated protein 4 3.32937
PARP3 poly (ADP-ribose) polymerase family, member 3 3.27261
PPP6C protein phosphatase 6, catalytic subunit 3.21143
RAB22A RAB22A, member RAS oncogene family 3.18928
TGFBI transforming growth factor, beta-induced, 68kDa 3.1676
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 3.05611
ELF2 E74-like factor 2 (ets domain transcription factor) 2.91722
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.90337
USP11 ubiquitin specific peptidase 11 2.9004
ARL4D ADP-ribosylation factor-like 4D 2.8908
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 2.87352
CALML4 calmodulin-like 4 2.80546
C20ORF24 chromosome 20 open reading frame 24 2.80146
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.71933
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.69953
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.68594
SUGP2 SURP and G patch domain containing 2 2.68551
CD40 CD40 molecule, TNF receptor superfamily member 5 2.67929
SEC23IP SEC23 interacting protein 2.67872
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.67627
KCTD2 potassium channel tetramerization domain containing 2 2.66416
UBE2N ubiquitin-conjugating enzyme E2N 2.65747
IQCK IQ motif containing K 2.6246
BIN3 bridging integrator 3 2.62398
ACADL acyl-CoA dehydrogenase, long chain 2.61289
FMR1 fragile X mental retardation 1 2.60513
VNN1 vanin 1 2.60153
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 2.56452
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 2.55104
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.53477
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 2.53417
SYTL2 synaptotagmin-like 2 2.52554
CAMLG calcium modulating ligand 2.52488
SH2B2 SH2B adaptor protein 2 2.52102
CHPF2 chondroitin polymerizing factor 2 2.49285
DCTN6 dynactin 6 2.49244
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.48787
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.48591
TSKU tsukushi, small leucine rich proteoglycan 2.4462
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 2.42304
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.40075
SUMO3 small ubiquitin-like modifier 3 2.39697
SEC11A SEC11 homolog A (S. cerevisiae) 2.39083
ZNF185 zinc finger protein 185 (LIM domain) 2.36174
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 2.35918
PLSCR1 phospholipid scramblase 1 2.35527
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 2.34441
AGMAT agmatine ureohydrolase (agmatinase) 2.33339
TMEM2 transmembrane protein 2 2.3174
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.31385
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 2.29214
ITGA1 integrin, alpha 1 2.28755
CYBB cytochrome b-245, beta polypeptide 2.28671
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 2.28089
LCK LCK proto-oncogene, Src family tyrosine kinase 2.25488
LRP10 low density lipoprotein receptor-related protein 10 2.24963
MR1 major histocompatibility complex, class I-related 2.23773
IFI16 interferon, gamma-inducible protein 16 2.23199
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.22666
SMCP sperm mitochondria-associated cysteine-rich protein 2.22165
EFCAB1 EF-hand calcium binding domain 1 2.21436
ACO2 aconitase 2, mitochondrial 2.20668
RFPL3 ret finger protein-like 3 2.20515
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene 2.1965
HIF3A hypoxia inducible factor 3, alpha subunit 2.18499
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.17563
SDC1 syndecan 1 2.17206
RPL13P5 ribosomal protein L13 pseudogene 5 2.17175
CD1C CD1c molecule 2.16439
NLGN4Y neuroligin 4, Y-linked 2.16133
PCSK7 proprotein convertase subtilisin/kexin type 7 2.15935
APH1B APH1B gamma secretase subunit 2.15543
DCTN5 dynactin 5 (p25) 2.15336
CCL8 chemokine (C-C motif) ligand 8 2.15324
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.15002
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 2.14622
LINC00950 long intergenic non-protein coding RNA 950 2.12234
SEC13 SEC13 homolog (S. cerevisiae) 2.11873
DCSTAMP dendrocyte expressed seven transmembrane protein 2.11669
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.09801
PNOC prepronociceptin 2.09392
DLG3 discs, large homolog 3 (Drosophila) 2.09186
ZNF423 zinc finger protein 423 2.07708
ZNF212 zinc finger protein 212 2.07613
ANO3 anoctamin 3 2.07171
BIRC3 baculoviral IAP repeat containing 3 2.06878
ADGRG1 adhesion G protein-coupled receptor G1 2.0655
HYI hydroxypyruvate isomerase (putative) 2.0568
C1RL complement component 1, r subcomponent-like 2.05634
MED7 mediator complex subunit 7 2.0547
BCL9 B-cell CLL/lymphoma 9 2.05368
GPR161 G protein-coupled receptor 161 2.04847
NRGN neurogranin (protein kinase C substrate, RC3) 2.04834
DNASE1L1 deoxyribonuclease I-like 1 2.04752
CHIA chitinase, acidic 2.04737
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 2.03955
SMYD2 SET and MYND domain containing 2 2.03806
WT1-AS WT1 antisense RNA 2.01769
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 2.01031
RBMS2 RNA binding motif, single stranded interacting protein 2 2.0047
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.00124
CREM cAMP responsive element modulator 1.99589
KREMEN2 kringle containing transmembrane protein 2 1.98448
IGF1R insulin-like growth factor 1 receptor 1.98287
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 1.98167
C3ORF14 chromosome 3 open reading frame 14 1.97944
GLOD4 glyoxalase domain containing 4 1.97652
UFSP2 UFM1-specific peptidase 2 1.96558
GDF5 growth differentiation factor 5 1.96217
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.95068
TNMD tenomodulin 1.94713
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.94069
FERMT1 fermitin family member 1 1.92719
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.92513
BHMT2 betaine--homocysteine S-methyltransferase 2 1.92254
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.92008
ICAM1 intercellular adhesion molecule 1 1.91602
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.91254
MPHOSPH8 M-phase phosphoprotein 8 1.90717
ANKRD6 ankyrin repeat domain 6 1.89521
GKN1 gastrokine 1 1.89374
ZNF292 zinc finger protein 292 1.8934
ETNPPL ethanolamine-phosphate phospho-lyase 1.89188
IQCE IQ motif containing E 1.88852
GPN1 GPN-loop GTPase 1 1.87868
LPAR2 lysophosphatidic acid receptor 2 1.8768
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.8737
PTK7 protein tyrosine kinase 7 (inactive) 1.87297
CDK19 cyclin-dependent kinase 19 1.8692
BRD3 bromodomain containing 3 1.86243
NXF1 nuclear RNA export factor 1 1.85782
TBCCD1 TBCC domain containing 1 1.85563
LRP1B low density lipoprotein receptor-related protein 1B 1.85468
TMCO1 transmembrane and coiled-coil domains 1 1.85406
UMPS uridine monophosphate synthetase 1.84823
GCC2 GRIP and coiled-coil domain containing 2 1.84354
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 1.84119
PHF10 PHD finger protein 10 1.83859
CES1 carboxylesterase 1 1.83468
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.82242
NNMT nicotinamide N-methyltransferase 1.82209
SNX3 sorting nexin 3 1.81752
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 1.81343
ZNF224 zinc finger protein 224 1.81033
BHLHE41 basic helix-loop-helix family, member e41 1.80824
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.8053
NDE1 nudE neurodevelopment protein 1 1.80526
RPL23A ribosomal protein L23a 1.8047
PLA2G10 phospholipase A2, group X 1.79682
LINC00094 long intergenic non-protein coding RNA 94 1.79555
BDKRB1 bradykinin receptor B1 1.79489
DPPA4 developmental pluripotency associated 4 1.78841
SVIL supervillin 1.78612
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.78448
MYLIP myosin regulatory light chain interacting protein 1.77591
PLAUR plasminogen activator, urokinase receptor 1.76892
TM9SF1 transmembrane 9 superfamily member 1 1.76748
LDB3 LIM domain binding 3 1.7634
CARTPT CART prepropeptide 1.76207
CRBN cereblon 1.76043
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.75808
ZC3H12A zinc finger CCCH-type containing 12A 1.75456
COCH cochlin 1.75221
ACP2 acid phosphatase 2, lysosomal 1.74791
STAP1 signal transducing adaptor family member 1 1.73886
GOLGA1 golgin A1 1.73342
MMP12 matrix metallopeptidase 12 1.73091
ARL5A ADP-ribosylation factor-like 5A 1.72908
PPAP2B phosphatidic acid phosphatase type 2B 1.72707
ERO1LB ERO1-like beta (S. cerevisiae) 1.72432
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.72393
ANG angiogenin, ribonuclease, RNase A family, 5 1.71485
MAPK13 mitogen-activated protein kinase 13 1.70869
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.70764
HOXB7 homeobox B7 1.70668
VAMP7 vesicle-associated membrane protein 7 1.70594
GRP gastrin-releasing peptide 1.69772
COL3A1 collagen, type III, alpha 1 1.69635
CLDN10 claudin 10 1.69101
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 1.68234
PTHLH parathyroid hormone-like hormone 1.68172
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 1.67927
FLRT2 fibronectin leucine rich transmembrane protein 2 1.67677
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.67458
TNR tenascin R 1.67282
STX7 syntaxin 7 1.67101
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.66926
RTN2 reticulon 2 1.66708
MOBP myelin-associated oligodendrocyte basic protein 1.66675
AK1 adenylate kinase 1 1.66447
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.65629
PDZD2 PDZ domain containing 2 1.64905
PCDH11Y protocadherin 11 Y-linked 1.64875
ACTL7A actin-like 7A 1.64784
FAM110D family with sequence similarity 110, member D 1.64618
ELF5 E74-like factor 5 (ets domain transcription factor) 1.64618
CLCA2 chloride channel accessory 2 1.64317
GCLM glutamate-cysteine ligase, modifier subunit 1.64223
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.63835
IL1R1 interleukin 1 receptor, type I 1.63703
RRAD Ras-related associated with diabetes 1.63442
UNG uracil-DNA glycosylase 1.63161
MFAP3 microfibrillar-associated protein 3 1.6293
CREBL2 cAMP responsive element binding protein-like 2 1.62759
BCAP29 B-cell receptor-associated protein 29 1.62544
SRR serine racemase 1.62122
DESI1 desumoylating isopeptidase 1 1.61735
ALPP alkaline phosphatase, placental 1.61663
STRADA STE20-related kinase adaptor alpha 1.60828
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 1.60738
MFSD12 major facilitator superfamily domain containing 12 1.60442
AVP arginine vasopressin 1.6043
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 1.59995
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 1.59882
SENP7 SUMO1/sentrin specific peptidase 7 1.59621
DENND4A DENN/MADD domain containing 4A 1.5953
TYK2 tyrosine kinase 2 1.58989
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 1.58777
TSHB thyroid stimulating hormone, beta 1.58414
RAB33A RAB33A, member RAS oncogene family 1.58216
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.5708
IGSF3 immunoglobulin superfamily, member 3 1.56504
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.56439
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.56183
LMBR1L limb development membrane protein 1-like 1.55827
CYLD cylindromatosis (turban tumor syndrome) 1.55627
DGUOK deoxyguanosine kinase 1.55495
TMC6 transmembrane channel-like 6 1.55061
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.54872
LAPTM5 lysosomal protein transmembrane 5 1.54576
TRNAU1AP tRNA selenocysteine 1 associated protein 1 1.54505
GUCY2C guanylate cyclase 2C 1.54498
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.54078
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 1.53941
KPNA1 karyopherin alpha 1 (importin alpha 5) 1.53655
BFSP1 beaded filament structural protein 1, filensin 1.53266
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1.53155
CBLN1 cerebellin 1 precursor 1.53134
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 1.52012
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.51681
OR10J1 olfactory receptor, family 10, subfamily J, member 1 1.51011
FRYL FRY-like 1.50881
RENBP renin binding protein 1.50792
CYTIP cytohesin 1 interacting protein 1.50702
GPNMB glycoprotein (transmembrane) nmb 1.50628
DTNA dystrobrevin, alpha 1.50433
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 1.50384
VTI1B vesicle transport through interaction with t-SNAREs 1B 1.50191
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.49424
CHN1 chimerin 1 1.49252
SP110 SP110 nuclear body protein 1.49184
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 1.49178
CHP2 calcineurin-like EF-hand protein 2 1.48902
PRDM14 PR domain containing 14 1.4883
ADAM5 ADAM metallopeptidase domain 5 (pseudogene) 1.48728
TMEM70 transmembrane protein 70 1.48547
LGI1 leucine-rich, glioma inactivated 1 1.48286
SAP30L-AS1 SAP30L antisense RNA 1 (head to head) 1.48221
SAP18 Sin3A-associated protein, 18kDa 1.48074
DCTPP1 dCTP pyrophosphatase 1 1.48054
NUP62CL nucleoporin 62kDa C-terminal like 1.48011
KLHL41 kelch-like family member 41 1.48
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.47123
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.47092
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 1.47073
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.46965
PITPNM3 PITPNM family member 3 1.46951
FAM214B family with sequence similarity 214, member B 1.46869
BICC1 BicC family RNA binding protein 1 1.46837
LIPC lipase, hepatic 1.46604
FGD1 FYVE, RhoGEF and PH domain containing 1 1.46438
FN3KRP fructosamine 3 kinase related protein 1.46276
JAK2 Janus kinase 2 1.4625
SORCS3 sortilin-related VPS10 domain containing receptor 3 1.46007
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.457
NFE2L3 nuclear factor, erythroid 2-like 3 1.45484
RAI1 retinoic acid induced 1 1.45288
EED embryonic ectoderm development 1.44958
MTF2 metal response element binding transcription factor 2 1.44866
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.44799
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 1.44696
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 1.4451
FSHB follicle stimulating hormone, beta polypeptide 1.44365
PAQR6 progestin and adipoQ receptor family member VI 1.44292
PLAA phospholipase A2-activating protein 1.44214
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 1.44143
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.43782
ADPGK ADP-dependent glucokinase 1.43578
ING4 inhibitor of growth family, member 4 1.43571
CLUL1 clusterin-like 1 (retinal) 1.43555
CASD1 CAS1 domain containing 1 1.4318
ECM1 extracellular matrix protein 1 1.43149
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 1.43106
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 1.42979
CD24 CD24 molecule 1.42782

decreased expression

Symbol Name Standardized Value
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -3.91089
RBBP5 retinoblastoma binding protein 5 -3.28326
RND1 Rho family GTPase 1 -3.20079
HIPK2 homeodomain interacting protein kinase 2 -3.14354
NPR1 natriuretic peptide receptor 1 -3.11074
ADAM10 ADAM metallopeptidase domain 10 -3.05581
ARPP19 cAMP-regulated phosphoprotein, 19kDa -2.99262
CTSF cathepsin F -2.92049
FHL5 four and a half LIM domains 5 -2.90079
RPL23AP53 ribosomal protein L23a pseudogene 53 -2.89057
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 -2.8798
GTPBP6 GTP binding protein 6 (putative) -2.86118
CSPP1 centrosome and spindle pole associated protein 1 -2.83109
GTPBP8 GTP-binding protein 8 (putative) -2.81222
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.76392
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -2.71359
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.70151
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 -2.66552
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -2.65572
IGLL1 immunoglobulin lambda-like polypeptide 1 -2.60289
PPA1 pyrophosphatase (inorganic) 1 -2.59559
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.593
FBRS fibrosin -2.58689
SUB1 SUB1 homolog (S. cerevisiae) -2.58344
SMC6 structural maintenance of chromosomes 6 -2.57486
RBM42 RNA binding motif protein 42 -2.56154
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.55518
TAZ tafazzin -2.545
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.53335
FKBP10 FK506 binding protein 10, 65 kDa -2.52936
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.51292
CUL9 cullin 9 -2.51229
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.50402
MIIP migration and invasion inhibitory protein -2.50301
PSKH1 protein serine kinase H1 -2.47528
GLO1 glyoxalase I -2.44169
SPRED2 sprouty-related, EVH1 domain containing 2 -2.39338
ALS2CL ALS2 C-terminal like -2.39264
CBFB core-binding factor, beta subunit -2.38742
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -2.36732
ADSS adenylosuccinate synthase -2.35747
CHMP2B charged multivesicular body protein 2B -2.34597
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -2.33992
ATN1 atrophin 1 -2.32626
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -2.31647
R3HCC1 R3H domain and coiled-coil containing 1 -2.29783
COL1A1 collagen, type I, alpha 1 -2.29069
SYNJ2 synaptojanin 2 -2.27807
TTPAL tocopherol (alpha) transfer protein-like -2.27646
PEX10 peroxisomal biogenesis factor 10 -2.2717
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.27073
PADI1 peptidyl arginine deiminase, type I -2.25895
PDGFB platelet-derived growth factor beta polypeptide -2.2548
INADL InaD-like (Drosophila) -2.24713
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 -2.23859
STAT5B signal transducer and activator of transcription 5B -2.21688
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -2.21485
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 -2.19799
NCAPH2 non-SMC condensin II complex, subunit H2 -2.18113
KPNA6 karyopherin alpha 6 (importin alpha 7) -2.17419
VEZT vezatin, adherens junctions transmembrane protein -2.16256
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide -2.15575
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -2.15535
NAP1L4 nucleosome assembly protein 1-like 4 -2.13625
RTN4 reticulon 4 -2.11335
HMGN1 high mobility group nucleosome binding domain 1 -2.11192
PREPL prolyl endopeptidase-like -2.10713
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -2.0966
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.08912
COL6A2 collagen, type VI, alpha 2 -2.07628
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -2.07548
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -2.06875
ADAM18 ADAM metallopeptidase domain 18 -2.06605
PKP4 plakophilin 4 -2.06523
S1PR2 sphingosine-1-phosphate receptor 2 -2.06389
SRPR signal recognition particle receptor (docking protein) -2.04178
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.03188
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -2.02265
IKZF5 IKAROS family zinc finger 5 (Pegasus) -2.02096
DLK2 delta-like 2 homolog (Drosophila) -2.02066
PRDM2 PR domain containing 2, with ZNF domain -2.01956
MPPED1 metallophosphoesterase domain containing 1 -2.01432
TRAPPC6A trafficking protein particle complex 6A -2.00608
ADSL adenylosuccinate lyase -1.98099
NECAP1 NECAP endocytosis associated 1 -1.97582
SP3P Sp3 transcription factor pseudogene -1.97488
MTERF1 mitochondrial transcription termination factor 1 -1.9705
STOM stomatin -1.9555
HR hair growth associated -1.95044
MTMR10 myotubularin related protein 10 -1.95025
KNOP1 lysine-rich nucleolar protein 1 -1.94877
ZCCHC14 zinc finger, CCHC domain containing 14 -1.94657
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -1.94304
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -1.94004
DOPEY2 dopey family member 2 -1.92756
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.92708
ARID3A AT rich interactive domain 3A (BRIGHT-like) -1.92615
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -1.92501
MUC3A mucin 3A, cell surface associated -1.92118
ELL2 elongation factor, RNA polymerase II, 2 -1.91852
PTGES3 prostaglandin E synthase 3 (cytosolic) -1.91374
ATP11A ATPase, class VI, type 11A -1.90756
TADA3 transcriptional adaptor 3 -1.90473
BLMH bleomycin hydrolase -1.90443
QSER1 glutamine and serine rich 1 -1.89826
TBK1 TANK-binding kinase 1 -1.89241
PDHX pyruvate dehydrogenase complex, component X -1.89103
PLEKHA5 pleckstrin homology domain containing, family A member 5 -1.88918
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 -1.88599
SYNPO2L synaptopodin 2-like -1.87987
PVT1 Pvt1 oncogene (non-protein coding) -1.87866
MARCO macrophage receptor with collagenous structure -1.87055
POU2F1 POU class 2 homeobox 1 -1.86842
HIST1H4A histone cluster 1, H4a -1.85977
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -1.85756
ADCY6 adenylate cyclase 6 -1.85158
ASIC2 acid sensing (proton gated) ion channel 2 -1.84981
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 -1.83519
WIZ widely interspaced zinc finger motifs -1.83039
BCL2L1 BCL2-like 1 -1.82956
RAN RAN, member RAS oncogene family -1.82448
DMC1 DNA meiotic recombinase 1 -1.82417
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -1.81955
HIST1H3C histone cluster 1, H3c -1.81165
HIPK3 homeodomain interacting protein kinase 3 -1.81092
MYBPH myosin binding protein H -1.80907
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -1.80892
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -1.80706
PLVAP plasmalemma vesicle associated protein -1.80094
PNMA3 paraneoplastic Ma antigen 3 -1.7988
HCRT hypocretin (orexin) neuropeptide precursor -1.79332
STAB1 stabilin 1 -1.78727
SPDEF SAM pointed domain containing ETS transcription factor -1.77998
NFASC neurofascin -1.77842
WEE1 WEE1 G2 checkpoint kinase -1.77216
IRF5 interferon regulatory factor 5 -1.77209
CD8B CD8b molecule -1.76335
IRGQ immunity-related GTPase family, Q -1.76054
FZD5 frizzled class receptor 5 -1.75707
C1ORF123 chromosome 1 open reading frame 123 -1.75085
HGD homogentisate 1,2-dioxygenase -1.74558
GLP2R glucagon-like peptide 2 receptor -1.7396
GRM3 glutamate receptor, metabotropic 3 -1.73661
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -1.73377
NPAS1 neuronal PAS domain protein 1 -1.73336
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -1.72996
PNISR PNN-interacting serine/arginine-rich protein -1.72919
RBP3 retinol binding protein 3, interstitial -1.72441
CPNE7 copine VII -1.72384
ADAP2 ArfGAP with dual PH domains 2 -1.71881
AKAP9 A kinase (PRKA) anchor protein 9 -1.71541
COASY CoA synthase -1.71266
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -1.71075
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene -1.7095
CDCA4 cell division cycle associated 4 -1.70864
PHF20 PHD finger protein 20 -1.70724
RPS4X ribosomal protein S4, X-linked -1.69749
CADM1 cell adhesion molecule 1 -1.69531
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -1.69517
ZNF814 zinc finger protein 814 -1.69372
ADPRH ADP-ribosylarginine hydrolase -1.69183
SRC SRC proto-oncogene, non-receptor tyrosine kinase -1.69018
PINK1 PTEN induced putative kinase 1 -1.68724
CCND2 cyclin D2 -1.68571
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.68434
RAX retina and anterior neural fold homeobox -1.68391
ZWINT ZW10 interacting kinetochore protein -1.67991
FGD6 FYVE, RhoGEF and PH domain containing 6 -1.67088
TBC1D10B TBC1 domain family, member 10B -1.67065
RARG retinoic acid receptor, gamma -1.67025
HIST1H2BL histone cluster 1, H2bl -1.66994
E2F1 E2F transcription factor 1 -1.66904
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.66712
IL17RC interleukin 17 receptor C -1.66681
SCARB1 scavenger receptor class B, member 1 -1.66031
NR2E3 nuclear receptor subfamily 2, group E, member 3 -1.65962
ELL elongation factor RNA polymerase II -1.65851
CLTB clathrin, light chain B -1.65596
BTF3 basic transcription factor 3 -1.65548
USP22 ubiquitin specific peptidase 22 -1.6456
ATF6B activating transcription factor 6 beta -1.64201
KRT37 keratin 37, type I -1.6347
PRDM8 PR domain containing 8 -1.63364
INE1 inactivation escape 1 (non-protein coding) -1.63064
CDKL5 cyclin-dependent kinase-like 5 -1.62653
ITGB7 integrin, beta 7 -1.62362
STOML2 stomatin (EPB72)-like 2 -1.62222
CCNE2 cyclin E2 -1.61907
KIAA0408 KIAA0408 -1.61348
DNAAF1 dynein, axonemal, assembly factor 1 -1.60644
CSF3R colony stimulating factor 3 receptor (granulocyte) -1.60598
PPCS phosphopantothenoylcysteine synthetase -1.60336
DMP1 dentin matrix acidic phosphoprotein 1 -1.59967
FN1 fibronectin 1 -1.59746
PTGER3 prostaglandin E receptor 3 (subtype EP3) -1.59743
TADA2A transcriptional adaptor 2A -1.59712
SGMS1 sphingomyelin synthase 1 -1.59704
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -1.59668
POM121L2 POM121 transmembrane nucleoporin-like 2 -1.59519
PMP2 peripheral myelin protein 2 -1.5906
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) -1.58782
PKD1 polycystic kidney disease 1 (autosomal dominant) -1.58644
CYSLTR1 cysteinyl leukotriene receptor 1 -1.57535
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.57425
BPIFA1 BPI fold containing family A, member 1 -1.57196
ARSA arylsulfatase A -1.5718
KIAA1661 KIAA1661 protein -1.56776
ALX3 ALX homeobox 3 -1.56723
YIPF2 Yip1 domain family, member 2 -1.56677
MYLK3 myosin light chain kinase 3 -1.56534
TRMT61A tRNA methyltransferase 61A -1.5651
GJB1 gap junction protein, beta 1, 32kDa -1.56343
AKAP13 A kinase (PRKA) anchor protein 13 -1.5634
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 -1.56118
GRAMD4 GRAM domain containing 4 -1.55974
ACVR2B-AS1 ACVR2B antisense RNA 1 -1.55474
BCAS3 breast carcinoma amplified sequence 3 -1.55455
MOG myelin oligodendrocyte glycoprotein -1.55132
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -1.55074
USP6NL USP6 N-terminal like -1.55072
COL5A2 collagen, type V, alpha 2 -1.54961
CPM carboxypeptidase M -1.54959
KLHL12 kelch-like family member 12 -1.54901
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.54589
SLURP1 secreted LY6/PLAUR domain containing 1 -1.54584
RIT2 Ras-like without CAAX 2 -1.53709
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -1.53308
ZNF250 zinc finger protein 250 -1.5329
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -1.53086
VGLL4 vestigial-like family member 4 -1.52921
LIG4 ligase IV, DNA, ATP-dependent -1.52202
ADRA1A adrenoceptor alpha 1A -1.52077
KIAA0319L KIAA0319-like -1.51899
RASAL2 RAS protein activator like 2 -1.51825
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -1.51486
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -1.51234
CACFD1 calcium channel flower domain containing 1 -1.51126
RAB9BP1 RAB9B, member RAS oncogene family pseudogene 1 -1.51045
OSGEP O-sialoglycoprotein endopeptidase -1.51037
NTN1 netrin 1 -1.50894
DTX3 deltex 3, E3 ubiquitin ligase -1.5085
RPS19 ribosomal protein S19 -1.50579
CTF1 cardiotrophin 1 -1.49727
AIRE autoimmune regulator -1.49535
MED20 mediator complex subunit 20 -1.48877
MKNK2 MAP kinase interacting serine/threonine kinase 2 -1.48874
CBX6 chromobox homolog 6 -1.48842
POU5F1P3 POU class 5 homeobox 1 pseudogene 3 -1.48669
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -1.48366
FGG fibrinogen gamma chain -1.48338
PGAM2 phosphoglycerate mutase 2 (muscle) -1.48253
MFGE8 milk fat globule-EGF factor 8 protein -1.47867
CRH corticotropin releasing hormone -1.47828
GSTZ1 glutathione S-transferase zeta 1 -1.47813
ZBTB32 zinc finger and BTB domain containing 32 -1.47758
HPCA hippocalcin -1.47067
HDAC11 histone deacetylase 11 -1.46845
NT5DC3 5'-nucleotidase domain containing 3 -1.4683
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -1.46805
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -1.46727
SIGLEC7 sialic acid binding Ig-like lectin 7 -1.46193
DKKL1 dickkopf-like 1 -1.45852
STAMBPL1 STAM binding protein-like 1 -1.45699
CXADR coxsackie virus and adenovirus receptor -1.45685
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -1.45456
C12ORF43 chromosome 12 open reading frame 43 -1.45424
CRTC1 CREB regulated transcription coactivator 1 -1.45415
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 -1.44681
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific -1.44519
BRSK2 BR serine/threonine kinase 2 -1.44447
MYL10 myosin, light chain 10, regulatory -1.44432
GRM8 glutamate receptor, metabotropic 8 -1.44223
EVC Ellis van Creveld protein -1.44177
GIGYF2 GRB10 interacting GYF protein 2 -1.4415
S100G S100 calcium binding protein G -1.441
PPIEL peptidylprolyl isomerase E-like pseudogene -1.43992
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.43869
PDGFA platelet-derived growth factor alpha polypeptide -1.43715
IFNA7 interferon, alpha 7 -1.43707
CAMP cathelicidin antimicrobial peptide -1.43564
HDLBP high density lipoprotein binding protein -1.43024
CD2AP CD2-associated protein -1.42924
SOX18 SRY (sex determining region Y)-box 18 -1.42829
HIP1R huntingtin interacting protein 1 related -1.42541
INSRR insulin receptor-related receptor -1.42404
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.42355
CEP152 centrosomal protein 152kDa -1.4229
GRHL2 grainyhead-like 2 (Drosophila) -1.42209
ZBTB16 zinc finger and BTB domain containing 16 -1.42164
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.42149
CAPN9 calpain 9 -1.42044
TRIM15 tripartite motif containing 15 -1.4199
ADRBK1 adrenergic, beta, receptor kinase 1 -1.41686
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -1.4137
INSR insulin receptor -1.41242
GAMT guanidinoacetate N-methyltransferase -1.41237
CCDC9 coiled-coil domain containing 9 -1.41188
PDE9A phosphodiesterase 9A -1.41076
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.40753
RAB36 RAB36, member RAS oncogene family -1.40738