TBX3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description T-box 3|This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6926)
External Link http://www.ncbi.nlm.nih.gov/gene/6926
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Genes

7 interacting proteins for TBX3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ELAVL1 ELAV like RNA binding protein 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC5 histone deacetylase 5
SOX2 SRY (sex determining region Y)-box 2
TOLLIP toll interacting protein