TBX5 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description T-box 5|This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6910)
Similar Terms
Downloads & Tools

Genes

98 target genes of the TBX5 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ACY3 aminoacylase 3
ADCK3 aarF domain containing kinase 3
ADGRL2 adhesion G protein-coupled receptor L2
ANK2 ankyrin 2, neuronal
ARHGAP32 Rho GTPase activating protein 32
AZI2 5-azacytidine induced 2
BCORL1 BCL6 corepressor-like 1
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BRS3 bombesin-like receptor 3
CCDC83 coiled-coil domain containing 83
CDH7 cadherin 7, type 2
DCDC5 doublecortin domain containing 5
DENND4C DENN/MADD domain containing 4C
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLL3 delta-like 3 (Drosophila)
DPF3 D4, zinc and double PHD fingers, family 3
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
EHBP1 EH domain binding protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERRFI1 ERBB receptor feedback inhibitor 1
EVA1C eva-1 homolog C (C. elegans)
EXOC6 exocyst complex component 6
FBRS fibrosin
FBXO2 F-box protein 2
FGF13-AS1 FGF13 antisense RNA 1
FOXA3 forkhead box A3
FOXB1 forkhead box B1
FTL ferritin, light polypeptide
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GHR growth hormone receptor
GLCCI1 glucocorticoid induced 1
GLIS3 GLIS family zinc finger 3
GLTSCR1L GLTSCR1-like
GMPS guanine monphosphate synthase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR142 G protein-coupled receptor 142
GPR21 G protein-coupled receptor 21
GPR75 G protein-coupled receptor 75
HEBP2 heme binding protein 2
HOXB4 homeobox B4
IPO9 importin 9
ITGA8 integrin, alpha 8
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LIN28A lin-28 homolog A (C. elegans)
LNX1-AS1 LNX1 antisense RNA 1
LOC646626 uncharacterized LOC646626
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MEIS1 Meis homeobox 1
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MIR4731 microRNA 4731
MIR5193 microRNA 5193
MIR581 microRNA 581
MIR7-1 microRNA 7-1
MLF2 myeloid leukemia factor 2
MMRN1 multimerin 1
MPRIP myosin phosphatase Rho interacting protein
MPZ myelin protein zero
MYO1B myosin IB
NDNF neuron-derived neurotrophic factor
NKX2-3 NK2 homeobox 3
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
NXT2 nuclear transport factor 2-like export factor 2
ODAM odontogenic, ameloblast asssociated
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OR1J2 olfactory receptor, family 1, subfamily J, member 2
PDZD2 PDZ domain containing 2
PEX14 peroxisomal biogenesis factor 14
PHC3 polyhomeotic homolog 3 (Drosophila)
PLEKHA7 pleckstrin homology domain containing, family A member 7
POU2F2 POU class 2 homeobox 2
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRLH prolactin releasing hormone
PTPRF protein tyrosine phosphatase, receptor type, F
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SAMD4B sterile alpha motif domain containing 4B
SCARNA7 small Cajal body-specific RNA 7
SEPT6 septin 6
SETD5 SET domain containing 5
SNORD113-4 small nucleolar RNA, C/D box 113-4
SNORD26 small nucleolar RNA, C/D box 26
SORCS1 sortilin-related VPS10 domain containing receptor 1
SPHKAP SPHK1 interactor, AKAP domain containing
STAG2 stromal antigen 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TCEAL2 transcription elongation factor A (SII)-like 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THSD7B thrombospondin, type I, domain containing 7B
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBG1 tubulin, gamma 1
USP47 ubiquitin specific peptidase 47
WDR46 WD repeat domain 46
WDR72 WD repeat domain 72
ZEB2 zinc finger E-box binding homeobox 2
ZMYM4 zinc finger, MYM-type 4