TC71 Gene Set

Dataset Achilles Cell Line Gene Essentiality Profiles
Category disease or phenotype associations
Type cell line
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Genes

553 gene knockdowns changing fitness of TC71 relative to other cell lines from the Achilles Cell Line Gene Essentiality Profiles dataset.

increased fitness

Symbol Name Standardized Value
NACA nascent polypeptide-associated complex alpha subunit 3.19303
RPSA ribosomal protein SA 3.10665
IL9R interleukin 9 receptor 3.01994
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 2.93337
TAS2R9 taste receptor, type 2, member 9 2.85089
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.7339
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.68346
RPS15 ribosomal protein S15 2.60681
FZD8 frizzled class receptor 8 2.51493
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.51288
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 2.46697
DCN decorin 2.4521
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 2.44803
PCCA propionyl CoA carboxylase, alpha polypeptide 2.43196
TRIM45 tripartite motif containing 45 2.40101
ACTC1 actin, alpha, cardiac muscle 1 2.36656
NEUROD4 neuronal differentiation 4 2.3655
ARL2-SNX15 ARL2-SNX15 readthrough (NMD candidate) 2.25686
PCDHB11 protocadherin beta 11 2.23751
SORCS3 sortilin-related VPS10 domain containing receptor 3 2.23365
DTX1 deltex 1, E3 ubiquitin ligase 2.2064
GPR142 G protein-coupled receptor 142 2.18486
SNX15 sorting nexin 15 2.18326
ATP13A2 ATPase type 13A2 2.16158
OAZ1 ornithine decarboxylase antizyme 1 2.15101
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 2.09729
CSNK2B casein kinase 2, beta polypeptide 2.09532
GDF10 growth differentiation factor 10 2.06905
CAPN2 calpain 2, (m/II) large subunit 2.05672
IL27RA interleukin 27 receptor, alpha 2.0227
TUFT1 tuftelin 1 1.99744
GPR31 G protein-coupled receptor 31 1.99148
PRPF38A pre-mRNA processing factor 38A 1.9674
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 1.96066
NME1-NME2 NME1-NME2 readthrough 1.92676
RAX2 retina and anterior neural fold homeobox 2 1.92609
OXSM 3-oxoacyl-ACP synthase, mitochondrial 1.9214
OLIG3 oligodendrocyte transcription factor 3 1.90924
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 1.90519
VTI1A vesicle transport through interaction with t-SNAREs 1A 1.9046
PHB prohibitin 1.88464
REG3A regenerating islet-derived 3 alpha 1.87312
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.83869
TUBGCP3 tubulin, gamma complex associated protein 3 1.83637
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 1.83247
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.83029
ZNF107 zinc finger protein 107 1.82334
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.82246
UNKL unkempt family zinc finger-like 1.82016
LEP leptin 1.81954
ATF6 activating transcription factor 6 1.80013
GPS1 G protein pathway suppressor 1 1.7935
CKAP5 cytoskeleton associated protein 5 1.7816
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.77722
FOXE3 forkhead box E3 1.76892
PEX5 peroxisomal biogenesis factor 5 1.75866
DTX2 deltex 2, E3 ubiquitin ligase 1.7573
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 1.7495
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.72963
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.72956
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5 1.72933
FZD9 frizzled class receptor 9 1.71941
INPP5K inositol polyphosphate-5-phosphatase K 1.71404
RPS12 ribosomal protein S12 1.71278
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.69808
URM1 ubiquitin related modifier 1 1.69485
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.69418
HSD11B1L hydroxysteroid (11-beta) dehydrogenase 1-like 1.64817
LSR lipolysis stimulated lipoprotein receptor 1.6413
PI4KAP1 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 1.63958
HAUS1 HAUS augmin-like complex, subunit 1 1.63819
JDP2 Jun dimerization protein 2 1.63587
CXCL16 chemokine (C-X-C motif) ligand 16 1.63488
TP73 tumor protein p73 1.62784
SOD3 superoxide dismutase 3, extracellular 1.6166
GPX5 glutathione peroxidase 5 1.6165
POU2AF1 POU class 2 associating factor 1 1.60299
L3MBTL2 l(3)mbt-like 2 (Drosophila) 1.60225
CD7 CD7 molecule 1.60189
GUCA2A guanylate cyclase activator 2A (guanylin) 1.59501
EFNA3 ephrin-A3 1.5926
LOC93432 1.57582
PDIK1L PDLIM1 interacting kinase 1 like 1.5756
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 1.57518
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 1.57481
MARCO macrophage receptor with collagenous structure 1.57364
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.57264
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 1.56913
FFAR3 free fatty acid receptor 3 1.56011
ZFP62 ZFP62 zinc finger protein 1.55532
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.55384
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.54511
GLP2R glucagon-like peptide 2 receptor 1.54034
RPP38 ribonuclease P/MRP 38kDa subunit 1.52473
MDFI MyoD family inhibitor 1.52445
RNH1 ribonuclease/angiogenin inhibitor 1 1.52325
CYBRD1 cytochrome b reductase 1 1.51274
HHEX hematopoietically expressed homeobox 1.50499
ADGRD2 adhesion G protein-coupled receptor D2 1.49307
SIRPA signal-regulatory protein alpha 1.48371
RNMT RNA (guanine-7-) methyltransferase 1.4834
UBTF upstream binding transcription factor, RNA polymerase I 1.48136
ADORA1 adenosine A1 receptor 1.47741
GALNS galactosamine (N-acetyl)-6-sulfatase 1.47698
QARS glutaminyl-tRNA synthetase 1.46789
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 1.46404
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.45946
UGDH UDP-glucose 6-dehydrogenase 1.45805
RPS8 ribosomal protein S8 1.45163
GCLC glutamate-cysteine ligase, catalytic subunit 1.45051
POLRMT polymerase (RNA) mitochondrial (DNA directed) 1.44992
PARK2 parkin RBR E3 ubiquitin protein ligase 1.44953
SP4 Sp4 transcription factor 1.44749
MAN1A2 mannosidase, alpha, class 1A, member 2 1.44658
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.44567
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) 1.43577
IL13 interleukin 13 1.42644
IL1B interleukin 1, beta 1.40735
RBP4 retinol binding protein 4, plasma 1.40651
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.40627
ALG12 ALG12, alpha-1,6-mannosyltransferase 1.40203
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.40191
LOC286297 uncharacterized LOC286297 1.40145
RAB43 RAB43, member RAS oncogene family 1.39729
TRIM41 tripartite motif containing 41 1.3969
CELF2 CUGBP, Elav-like family member 2 1.3915
ISY1-RAB43 ISY1-RAB43 readthrough 1.38859
HMSD histocompatibility (minor) serpin domain containing 1.38841
SAMD4B sterile alpha motif domain containing 4B 1.3872
MAT1A methionine adenosyltransferase I, alpha 1.37616
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 1.37591
RNASEH2A ribonuclease H2, subunit A 1.37159
ZNF273 zinc finger protein 273 1.36219
ZRANB2 zinc finger, RAN-binding domain containing 2 1.36116
KRT17 keratin 17, type I 1.36025
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 1.35584
GAL galanin/GMAP prepropeptide 1.35108
POLE polymerase (DNA directed), epsilon, catalytic subunit 1.34884
RASAL1 RAS protein activator like 1 (GAP1 like) 1.34683
TSHZ3 teashirt zinc finger homeobox 3 1.34514
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 1.3364
ABHD2 abhydrolase domain containing 2 1.32964
SYTL2 synaptotagmin-like 2 1.32527
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.32129
PCSK6 proprotein convertase subtilisin/kexin type 6 1.32032
FOXI1 forkhead box I1 1.31976
ACVRL1 activin A receptor type II-like 1 1.31696
RND3 Rho family GTPase 3 1.31628
HIATL1 hippocampus abundant transcript-like 1 1.31407
LPAR2 lysophosphatidic acid receptor 2 1.30984
SENP8 SUMO/sentrin specific peptidase family member 8 1.30338
RBP5 retinol binding protein 5, cellular 1.30196
C5AR1 complement component 5a receptor 1 1.29877
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.29759
TLX1 T-cell leukemia homeobox 1 1.29359
NXF1 nuclear RNA export factor 1 1.29163
CCR10 chemokine (C-C motif) receptor 10 1.29062
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 1.28296
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.28272
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 1.27381
SET SET nuclear proto-oncogene 1.27224
CCDC146 coiled-coil domain containing 146 1.27189
FBN2 fibrillin 2 1.2707
PRCC papillary renal cell carcinoma (translocation-associated) 1.2704
AGBL2 ATP/GTP binding protein-like 2 1.26986
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 1.26979
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.26606
BCL2L10 BCL2-like 10 (apoptosis facilitator) 1.26394
RPS25 ribosomal protein S25 1.26176
PHF11 PHD finger protein 11 1.26096
IKZF2 IKAROS family zinc finger 2 (Helios) 1.25942
TUBG1 tubulin, gamma 1 1.25917
TOPBP1 topoisomerase (DNA) II binding protein 1 1.25802
RPS17 ribosomal protein S17 1.25759
MYO1A myosin IA 1.25693
GPR35 G protein-coupled receptor 35 1.25219
RAB40B RAB40B, member RAS oncogene family 1.24757
TUSC2 tumor suppressor candidate 2 1.24574
POT1 protection of telomeres 1 1.24568
PI4KAP2 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2 1.24419
PITX3 paired-like homeodomain 3 1.24318
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.236
ITGB4 integrin, beta 4 1.23584
ODC1 ornithine decarboxylase 1 1.23516
RSG1 REM2 and RAB-like small GTPase 1 1.23151
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 1.2312
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.22863
EFHC1 EF-hand domain (C-terminal) containing 1 1.22724
CELA2B chymotrypsin-like elastase family, member 2B 1.22587
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.21831
DLX1 distal-less homeobox 1 1.21748
CHRM4 cholinergic receptor, muscarinic 4 1.2169
MED13L mediator complex subunit 13-like 1.21128
CDC7 cell division cycle 7 1.20604
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.2059
LRP3 low density lipoprotein receptor-related protein 3 1.20229
ZNF490 zinc finger protein 490 1.20117
MNX1 motor neuron and pancreas homeobox 1 1.19848
ZCCHC13 zinc finger, CCHC domain containing 13 1.19328
CDX4 caudal type homeobox 4 1.19162
EHMT1 euchromatic histone-lysine N-methyltransferase 1 1.19144
GUCA1A guanylate cyclase activator 1A (retina) 1.19141
MORC3 MORC family CW-type zinc finger 3 1.18529
MICU1 mitochondrial calcium uptake 1 1.18087
FOXR1 forkhead box R1 1.18027
MUSK muscle, skeletal, receptor tyrosine kinase 1.17925
EIF3G eukaryotic translation initiation factor 3, subunit G 1.17525
RPS11 ribosomal protein S11 1.17523
RUVBL1 RuvB-like AAA ATPase 1 1.17392
EEF2 eukaryotic translation elongation factor 2 1.17304
MMP25 matrix metallopeptidase 25 1.17141
ETV7 ets variant 7 1.16388
TAS1R2 taste receptor, type 1, member 2 1.16258
PTPN7 protein tyrosine phosphatase, non-receptor type 7 1.16189
PSKH1 protein serine kinase H1 1.15951
EPHA8 EPH receptor A8 1.15942
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 1.1585
PRKCI protein kinase C, iota 1.15466
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7 1.15288
CCL14 chemokine (C-C motif) ligand 14 1.14848
ING2 inhibitor of growth family, member 2 1.14714
CAMKV CaM kinase-like vesicle-associated 1.14501
SLC39A1 solute carrier family 39 (zinc transporter), member 1 1.14362
KARS lysyl-tRNA synthetase 1.14242
LIG3 ligase III, DNA, ATP-dependent 1.14156
RPS9 ribosomal protein S9 1.13853
TPSG1 tryptase gamma 1 1.13776
IGBP1 immunoglobulin (CD79A) binding protein 1 1.13725
RHAG Rh-associated glycoprotein 1.13593
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 1.13002
NF1 neurofibromin 1 1.1289
RAB36 RAB36, member RAS oncogene family 1.12067
GOPC golgi-associated PDZ and coiled-coil motif containing 1.11754
PBX1 pre-B-cell leukemia homeobox 1 1.11697
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 1.11694
PRICKLE4 prickle homolog 4 (Drosophila) 1.11293
GPX4 glutathione peroxidase 4 1.10945
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.10851
SSRP1 structure specific recognition protein 1 1.10781
ACTN4 actinin, alpha 4 1.10499
CDH3 cadherin 3, type 1, P-cadherin (placental) 1.10459
TSHZ1 teashirt zinc finger homeobox 1 1.103
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.10176
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.095
MSL2 male-specific lethal 2 homolog (Drosophila) 1.09491
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.09486
NAT10 N-acetyltransferase 10 (GCN5-related) 1.094
HIST1H3G histone cluster 1, H3g 1.0923
RASL10A RAS-like, family 10, member A 1.0899
KPNA3 karyopherin alpha 3 (importin alpha 4) 1.08903
MASTL microtubule associated serine/threonine kinase-like 1.08506
PLCD3 phospholipase C, delta 3 1.08448
SRRM1 serine/arginine repetitive matrix 1 1.08403
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.08031
FLNB filamin B, beta 1.08002
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.07939
CLDN18 claudin 18 1.07902
RAB5B RAB5B, member RAS oncogene family 1.07505
ARL9 ADP-ribosylation factor-like 9 1.07201
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 1.07158
PCBP1 poly(rC) binding protein 1 1.07106
ZMIZ1 zinc finger, MIZ-type containing 1 1.07029
TACC3 transforming, acidic coiled-coil containing protein 3 1.06942
SFPQ splicing factor proline/glutamine-rich 1.06864
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 1.0679
SOS1 son of sevenless homolog 1 (Drosophila) 1.06589
CDC37 cell division cycle 37 1.06494
CAMK1D calcium/calmodulin-dependent protein kinase ID 1.0647
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.05952
PRG3 proteoglycan 3 1.05596
SLC25A40 solute carrier family 25, member 40 1.05403
ZNF773 zinc finger protein 773 1.05002
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.04506
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 1.04234
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.04186
MTL5 metallothionein-like 5, testis-specific (tesmin) 1.04007
GLUL glutamate-ammonia ligase 1.03976
CYB561 cytochrome b561 1.03833
CDC5L cell division cycle 5-like 1.03626
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.03545
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 1.0342
TTLL4 tubulin tyrosine ligase-like family member 4 1.03396
ITPK1 inositol-tetrakisphosphate 1-kinase 1.03258
PGM5 phosphoglucomutase 5 1.03076
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.02842
GYS2 glycogen synthase 2 (liver) 1.02818
TNP1 transition protein 1 (during histone to protamine replacement) 1.02763
SOX18 SRY (sex determining region Y)-box 18 1.02758
MED19 mediator complex subunit 19 1.02596
DCLK3 doublecortin-like kinase 3 1.02457
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.02359
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 1.02224
OR4K17 olfactory receptor, family 4, subfamily K, member 17 1.02047
FNDC3B fibronectin type III domain containing 3B 1.01944
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.01862
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.01669
DEC1 deleted in esophageal cancer 1 1.01553
NCS1 neuronal calcium sensor 1 1.01513
DMBX1 diencephalon/mesencephalon homeobox 1 1.01438
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.01073
LRP1B low density lipoprotein receptor-related protein 1B 1.00764
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 1.00642
TSLP thymic stromal lymphopoietin 1.00249
SPTBN4 spectrin, beta, non-erythrocytic 4 1.00185
GJB1 gap junction protein, beta 1, 32kDa 1.00107
PCDHB9 protocadherin beta 9 1.00053
RPS4X ribosomal protein S4, X-linked 1.00021

decreased fitness

Symbol Name Standardized Value
PROC protein C (inactivator of coagulation factors Va and VIIIa) -2.91048
NRP2 neuropilin 2 -2.90733
EVX1 even-skipped homeobox 1 -2.82343
RNF148 ring finger protein 148 -2.71787
MMP8 matrix metallopeptidase 8 -2.57164
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.45791
LMO7 LIM domain 7 -2.39149
OXSR1 oxidative stress responsive 1 -2.37631
MINK1 misshapen-like kinase 1 -2.35743
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 -2.2928
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.24644
XBP1 X-box binding protein 1 -2.20162
LIPH lipase, member H -2.19975
RBMS1 RNA binding motif, single stranded interacting protein 1 -2.14915
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 -2.14544
RNF17 ring finger protein 17 -2.12537
PAX9 paired box 9 -2.0718
GJA5 gap junction protein, alpha 5, 40kDa -2.0579
H2AFZ H2A histone family, member Z -2.02361
GPR151 G protein-coupled receptor 151 -2.007
CBX7 chromobox homolog 7 -1.97044
DCLRE1B DNA cross-link repair 1B -1.96077
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) -1.94228
PHF3 PHD finger protein 3 -1.94009
HOXB8 homeobox B8 -1.93537
BIRC2 baculoviral IAP repeat containing 2 -1.92692
OR8G5 olfactory receptor, family 8, subfamily G, member 5 -1.92224
ERCC8 excision repair cross-complementation group 8 -1.91549
RGS18 regulator of G-protein signaling 18 -1.90814
CAPN12 calpain 12 -1.90539
KIAA1804 mixed lineage kinase 4 -1.89719
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -1.89042
CECR1 cat eye syndrome chromosome region, candidate 1 -1.89008
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.82518
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.82162
CDKL4 cyclin-dependent kinase-like 4 -1.80708
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -1.80649
ATR ATR serine/threonine kinase -1.78395
EPHB1 EPH receptor B1 -1.76968
FAF2 Fas associated factor family member 2 -1.76909
CD99 CD99 molecule -1.74057
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 -1.73672
PTPRM protein tyrosine phosphatase, receptor type, M -1.73313
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -1.72759
STAMBPL1 STAM binding protein-like 1 -1.72683
MSMO1 methylsterol monooxygenase 1 -1.72032
SEPT3 septin 3 -1.71586
CTSA cathepsin A -1.71005
PMF1 polyamine-modulated factor 1 -1.68681
TGIF2 TGFB-induced factor homeobox 2 -1.67496
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -1.65374
ABLIM1 actin binding LIM protein 1 -1.6519
ZNF345 zinc finger protein 345 -1.64241
CLK2 CDC-like kinase 2 -1.63005
ARNTL aryl hydrocarbon receptor nuclear translocator-like -1.62381
MAT2B methionine adenosyltransferase II, beta -1.60892
PROKR2 prokineticin receptor 2 -1.58206
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 -1.57994
TNNC2 troponin C type 2 (fast) -1.56051
PRMT1 protein arginine methyltransferase 1 -1.56009
PBK PDZ binding kinase -1.5543
LZIC leucine zipper and CTNNBIP1 domain containing -1.54957
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.54334
ADGRE5 adhesion G protein-coupled receptor E5 -1.543
MCHR1 melanin-concentrating hormone receptor 1 -1.54069
IFNA6 interferon, alpha 6 -1.51242
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -1.51194
IKZF4 IKAROS family zinc finger 4 (Eos) -1.50664
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -1.50593
AHCTF1 AT hook containing transcription factor 1 -1.49924
FADS6 fatty acid desaturase 6 -1.48512
ZNF860 zinc finger protein 860 -1.48344
ACTL8 actin-like 8 -1.48267
ATM ATM serine/threonine kinase -1.46864
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -1.46345
ADHFE1 alcohol dehydrogenase, iron containing, 1 -1.46142
RPS6KL1 ribosomal protein S6 kinase-like 1 -1.4493
ZFX zinc finger protein, X-linked -1.44758
TBX5 T-box 5 -1.44742
USP49 ubiquitin specific peptidase 49 -1.44158
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.44137
PCDHA8 protocadherin alpha 8 -1.43967
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 -1.43775
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) -1.43041
TNK2 tyrosine kinase, non-receptor, 2 -1.42976
ZNF257 zinc finger protein 257 -1.41535
PA2G4 proliferation-associated 2G4, 38kDa -1.41482
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -1.40815
IMPACT impact RWD domain protein -1.40776
ZNF234 zinc finger protein 234 -1.40507
LHB luteinizing hormone beta polypeptide -1.40295
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -1.38982
DRD2 dopamine receptor D2 -1.3887
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) -1.38438
CTTN cortactin -1.38223
CD302 CD302 molecule -1.37832
OR2G3 olfactory receptor, family 2, subfamily G, member 3 -1.37785
GLUD2 glutamate dehydrogenase 2 -1.36806
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -1.36318
RGN regucalcin -1.36206
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 -1.35729
ELAVL2 ELAV like neuron-specific RNA binding protein 2 -1.35653
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -1.35581
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.3523
TPTE transmembrane phosphatase with tensin homology -1.35037
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -1.34734
SNX2 sorting nexin 2 -1.34689
ISL1 ISL LIM homeobox 1 -1.33334
VANGL1 VANGL planar cell polarity protein 1 -1.32828
BATF basic leucine zipper transcription factor, ATF-like -1.32525
DUSP22 dual specificity phosphatase 22 -1.32151
RNASE8 ribonuclease, RNase A family, 8 -1.32039
SETBP1 SET binding protein 1 -1.32004
MYLK3 myosin light chain kinase 3 -1.31829
MNAT1 MNAT CDK-activating kinase assembly factor 1 -1.31814
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.3162
CHI3L2 chitinase 3-like 2 -1.31477
SNAPIN SNAP-associated protein -1.31072
ETFDH electron-transferring-flavoprotein dehydrogenase -1.30763
ZBTB16 zinc finger and BTB domain containing 16 -1.30638
TPO thyroid peroxidase -1.30206
TCL1A T-cell leukemia/lymphoma 1A -1.30152
WDR90 WD repeat domain 90 -1.29519
ARID3A AT rich interactive domain 3A (BRIGHT-like) -1.29006
YPEL2 yippee-like 2 (Drosophila) -1.28675
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.28669
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -1.28512
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 -1.28328
TCEAL1 transcription elongation factor A (SII)-like 1 -1.28103
ECI2 enoyl-CoA delta isomerase 2 -1.27514
TTC23 tetratricopeptide repeat domain 23 -1.27377
CBX2 chromobox homolog 2 -1.27198
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -1.26937
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -1.26704
GARS glycyl-tRNA synthetase -1.26411
OR51T1 olfactory receptor, family 51, subfamily T, member 1 -1.26255
HSDL2 hydroxysteroid dehydrogenase like 2 -1.25984
STK3 serine/threonine kinase 3 -1.24782
PRF1 perforin 1 (pore forming protein) -1.24506
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -1.24285
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.23933
TSPAN17 tetraspanin 17 -1.23901
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -1.23341
CBR1 carbonyl reductase 1 -1.22817
TRPM2 transient receptor potential cation channel, subfamily M, member 2 -1.22769
CALB1 calbindin 1, 28kDa -1.21865
MYNN myoneurin -1.21637
NPC1 Niemann-Pick disease, type C1 -1.21629
S100A10 S100 calcium binding protein A10 -1.21343
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -1.21198
COTL1 coactosin-like F-actin binding protein 1 -1.204
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.20312
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -1.20091
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -1.1991
EPHA7 EPH receptor A7 -1.1944
INSR insulin receptor -1.19216
ZNF623 zinc finger protein 623 -1.18617
AANAT aralkylamine N-acetyltransferase -1.18068
STRN4 striatin, calmodulin binding protein 4 -1.17976
CRYBB2 crystallin, beta B2 -1.17959
IGF1R insulin-like growth factor 1 receptor -1.17794
PCDHAC1 protocadherin alpha subfamily C, 1 -1.17018
WIF1 WNT inhibitory factor 1 -1.16657
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 -1.16585
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -1.16511
PCDHA10 protocadherin alpha 10 -1.16379
KDM4A lysine (K)-specific demethylase 4A -1.15938
MGMT O-6-methylguanine-DNA methyltransferase -1.15772
MTMR1 myotubularin related protein 1 -1.15374
TMEM9 transmembrane protein 9 -1.1523
GAP43 growth associated protein 43 -1.14987
SAR1B secretion associated, Ras related GTPase 1B -1.14577
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 -1.1418
MTNR1B melatonin receptor 1B -1.14084
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -1.14055
DBNL drebrin-like -1.14048
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -1.13661
HSF1 heat shock transcription factor 1 -1.1365
TESK2 testis-specific kinase 2 -1.13481
TAAR6 trace amine associated receptor 6 -1.1293
ACP6 acid phosphatase 6, lysophosphatidic -1.12727
IFI30 interferon, gamma-inducible protein 30 -1.12336
USP17L5 ubiquitin specific peptidase 17-like family member 5 -1.12169
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -1.12128
RGS16 regulator of G-protein signaling 16 -1.1203
ZEB2 zinc finger E-box binding homeobox 2 -1.11942
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.11838
ALG10B ALG10B, alpha-1,2-glucosyltransferase -1.11773
CCND1 cyclin D1 -1.11705
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -1.11259
POC1B-GALNT4 POC1B-GALNT4 readthrough -1.11178
DLL3 delta-like 3 (Drosophila) -1.11088
RBKS ribokinase -1.10984
ZNF805 zinc finger protein 805 -1.10537
TMEM209 transmembrane protein 209 -1.10284
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -1.0999
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -1.09256
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -1.08937
CHD9 chromodomain helicase DNA binding protein 9 -1.0893
HNF4G hepatocyte nuclear factor 4, gamma -1.08642
RHBDD2 rhomboid domain containing 2 -1.08359
TNPO2 transportin 2 -1.08083
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -1.07623
AWAT2 acyl-CoA wax alcohol acyltransferase 2 -1.07569
LOC100506859 -1.07459
ZNF281 zinc finger protein 281 -1.07431
RNF39 ring finger protein 39 -1.07387
BEGAIN brain-enriched guanylate kinase-associated -1.07338
PM20D1 peptidase M20 domain containing 1 -1.06825
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -1.06402
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -1.06384
PAPPA2 pappalysin 2 -1.06152
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -1.05989
AKAP10 A kinase (PRKA) anchor protein 10 -1.05849
LDHB lactate dehydrogenase B -1.05571
RAB14 RAB14, member RAS oncogene family -1.0551
INSRR insulin receptor-related receptor -1.05108
ANXA4 annexin A4 -1.05047
HOMER2 homer scaffolding protein 2 -1.04948
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -1.04913
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 -1.04871
IGSF8 immunoglobulin superfamily, member 8 -1.04767
TCEA3 transcription elongation factor A (SII), 3 -1.04312
ZNF322P1 zinc finger protein 322 pseudogene 1 -1.04183
RNF13 ring finger protein 13 -1.04181
HIST1H2BB histone cluster 1, H2bb -1.04157
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -1.04098
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.04
ACSL4 acyl-CoA synthetase long-chain family member 4 -1.03904
ZNF484 zinc finger protein 484 -1.03306
BARHL1 BarH-like homeobox 1 -1.03272
CCL26 chemokine (C-C motif) ligand 26 -1.03186
MBD6 methyl-CpG binding domain protein 6 -1.03008
RHOQ ras homolog family member Q -1.02744
GUSBP1 glucuronidase, beta pseudogene 1 -1.02495
OR52L1 olfactory receptor, family 52, subfamily L, member 1 -1.02454
USP17L3 ubiquitin specific peptidase 17-like family member 3 -1.02359
GPR160 G protein-coupled receptor 160 -1.02059
ISX intestine-specific homeobox -1.01968
NUAK1 NUAK family, SNF1-like kinase, 1 -1.01897
PCDHA4 protocadherin alpha 4 -1.01783
JUNB jun B proto-oncogene -1.01722
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -1.00949
HSPA1A heat shock 70kDa protein 1A -1.009
EVPL envoplakin -1.00513
LALBA lactalbumin, alpha- -1.00091